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77/100

✓ Peer-reviewed alzhub usefulness score 77 out of 100. Mild cognitive impairment

Topic: Risk, prevention and care in population studies

Because of the significant ramifications of falls, many interventions have been proposed, but few have aimed to prevent falls via an integrated approach targeting both motor and cognitive function. In the 6 months after training, the incident rate was significantly lower in the treadmill training plus VR group than it had been before training (6·00 [95% CI 4·36-8·25] falls per 6 months; p Interpretation In a diverse group of older adults at high risk for falls, treadmill training plus VR led to reduced fall rates compared with treadmill training alone.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Mirelman, A., Rochester, L., Maidan, I., Del Din, S., Alcock, L., Nieuwhof, F., et al. (2016). Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial. Lancet (London, England). https://doi.org/10.1016/s0140-6736(16)31325-3

Vancouver

Mirelman A, Rochester L, Maidan I, Del Din S, Alcock L, Nieuwhof F, et al. Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial. Lancet (London, England). 2016. doi:10.1016/s0140-6736(16)31325-3. PMID: 27524393.

BibTeX

@article{mirelman2016-27524393,
  author  = {Mirelman, A. and Rochester, L. and Maidan, I. and Del Din, S. and Alcock, L. and Nieuwhof, F. and Rikkert, M. O. and Bloem, B. R. and others},
  title   = {{Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial}},
  journal = {Lancet (London, England)},
  year    = {2016},
  doi     = {10.1016/s0140-6736(16)31325-3},
  pmid    = {27524393},
  url     = {https://doi.org/10.1016/s0140-6736(16)31325-3}
}

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Key findings

Because of the significant ramifications of falls, many interventions have been proposed, but few have aimed to prevent falls via an integrated approach targeting both motor and cognitive function.
In the 6 months after training, the incident rate was significantly lower in the treadmill training plus VR group than it had been before training (6·00 [95% CI 4·36-8·25] falls per 6 months; p<0·0001 vs before training), whereas the incident rate did not decrease significantly in the treadmill training alone group (8·27 [5·55-12·31] falls per 6 months; p=0·49). 6 months after the end of training, the incident rate of falls was also significantly lower in the treadmill training plus VR group than in the treadmill training group (incident rate ratio 0·58, 95% CI 0·36-0·96; p=0·033).

Why it matters

In older adults at high risk of falls, treadmill training combined with a non-immersive virtual reality component reduced fall rates more than treadmill training alone. This is about preventing falls, not about treating, curing, or preventing Alzheimer's disease.

Study details

Study designrandomized controlled trial
Participants154
Evidence strengthHigh

How this study scored 77/100

Published in a top-tier journal, and it is a randomised controlled trial. Scored zero for effect reported because the record does not state it.

Component	Points	Why
Journal tier	10 / 10	Tier 1 — top-tier general journal (Lancet (London, England))
Journal's citation record	4 / 4	The Lancet: journal h-index 1,205 (OpenAlex, 2026-10-29)
Study design	11 / 12	A randomised controlled trial
Strength of evidence	5 / 5	Rated “high” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2016 — within 20 year(s) of the newest study here
Sample size	2 / 4	154 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	1 / 2	Randomised (as stated in the record)
Times cited	6 / 7	Cited 496 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	41.3 citations a year over 12 year(s) since 2016
Impact for its field and year	6 / 6	Cited 99.3× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 3 other studies in this library
Still being cited	3 / 4	Cited 159 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Jeffrey M. Hausdorff: h-index 116 (OpenAlex, whole career)
Institution's track record	1 / 3	KU Leuven: institution h-index 1,386 (OpenAlex)
Multi-centre collaboration	2 / 3	OpenAlex lists 8 institution(s) in 5 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 27524393)
Free to read	0 / 2	Behind a paywall — scores zero
Total	77 / 100	—

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