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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,826–15,850 of 27,380 studies, newest first · page 634 of 1096.

September 2016 13

  1. 2016-09-01

    205 PHYSICAL ACTIVITY MODULATES GEOGRAPHICAL VARIATIONS IN COGNITIVE AGEING: RESULTS FROM THE IRISH LONGITUDINAL STUDY ON AGEING

    ✓ Peer-reviewed Risk factors Age and Ageing

    Key finding: The results support the hypothesis that engaging in physical activity can compensate for urban-rural differences in cognitive performance in ageing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-09-01

    A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Deep brain stimulation (DBS) is used to modulate the activity of dysfunctional brain circuits. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-09-01

    TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance

    ✓ Peer-reviewed TREM2 and immune genetics EMBO molecular medicine

    Key finding: Antibodies against amyloid β-peptide (Aβ) bind to amyloid plaques and induce their clearance by microglia via Fc receptor-mediated phagocytosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-09-01

    Targeting innate immunity for neurodegenerative disorders of the central nervous system

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: This mini review series originated from the 4th Venusberg Meeting on Neuroinflammation held in Bonn, Germany, 7-9th May 2015, presenting updates on innate immunity in acute brain injury and chronic neurodegenerative disorders, such as traumatic brain injury and Alzheimer disease, on the role of astrocytes and microglia, as well as technical developments that may help elucidate neuroinflammatory mechanisms and establish clinical relevance. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-09-01

    Application of advanced machine learning methods on resting-state fMRI network for identification of mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Brain imaging and behavior

    Key finding: In addition, results based on the parcellation of 264 regions were compared to that of the automated anatomical labeling atlas (AAL), consisted of 90 regions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-09-01

    Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

    ✓ Peer-reviewed How common it is JAMA neurology

    Key finding: Pooled clinical and neuropathologic data from 3 prospective cohort studies indicate that TBI with LOC is associated with risk for Lewy body accumulation, progression of parkinsonism, and PD, but not dementia, AD, neuritic plaques, or neurofibrillary tangles. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-09-01

    Sleep Duration and White Matter Quality in Middle-Aged Adults

    ✓ Peer-reviewed Disparities Sleep

    Key finding: Study objectives Sleep duration has been associated with risk of dementia and stroke, but few studies have investigated the relationship between sleep duration and brain MRI measures, particularly in middle age. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-09-01

    Continuity of Care and Health Care Utilization in Older Adults With Dementia in Fee-for-Service Medicare

    ✓ Peer-reviewed Caregiving JAMA internal medicine

    Key finding: Beneficiaries with dementia who had lower levels of continuity of care were younger, had a higher income, and had more comorbid medical conditions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-09-01

    Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy

    ✓ Peer-reviewed Getting a diagnosis JAMA neurology

    Key finding: Moreover, the presence of Aβ+ was associated with an elevated [18F]-AV-1451 SUVR in AD cortical signature regions (Aβ+ participants: mean [SD], 1.3 [0.3]; Aβ- participants: 1.1 [0.1]; F = 4.3, P = .04) but not in the hippocampus. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-09-01

    Update on cerebral small vessel disease: a dynamic whole-brain disease

    ✓ Peer-reviewed Getting a diagnosis Stroke and vascular neurology

    Key finding: However, variations in the use of definition and terms of these features have probably caused confusion and difficulties in interpreting results of previous studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-09-01

    Diabetes mellitus and cognitive impairments

    ✓ Peer-reviewed Prevention and risk World journal of diabetes

    Key finding: Anti-diabetic medications especially Insulin may have a role in the management of cognitive dysfunction and dementia but further investigation is needed to validate these findings.

    Full summary, score breakdown and related studies → Original source

  12. 2016-09-01

    Stroke, Vascular Dementia, and Alzheimer's Disease: Molecular Links

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: The pathophysiology of ischemic stroke is complex and recent molecular, cellular, and animal models and postmortem brain studies have revealed that multiple cellular changes have been implicated, including oxidative stress/mitochondrial dysfunction, inflammatory responses, micro RNA alterations, and marked changes in brain proteins. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2016-09-01

    Cognitive Reserve and the Prevention of Dementia: the Role of Physical and Cognitive Activities

    ✓ Peer-reviewed Prevention and risk Current psychiatry reports

    Key finding: Recent findings Both of these leisure-time activities were associated with significant reductions in the risk of dementia in longitudinal studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

August 2016 12

  1. 2016-08-31

    Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: Amy+ patients showed higher levels of pro-inflammatory cytokines (IL-6, CXCL2, NLRP3, and IL-1β) compared with both controls and with Amy- patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-08-31

    Estimated Budget Impact of Increased Use of Mirabegron, A Novel Treatment for Overactive Bladder

    ✓ Peer-reviewed Health systems and care delivery Journal of Managed Care & Specialty Pharmacy

    Key finding: Primary analysis calculated the impact of increasing the use of mirabegron from 4.5% to 5.3%, 7.1%, and 9.4% in years 1, 2, and 3, respectively, among oral pharmacological OAB treatments that included generic and branded antimuscarinics: oxybutynin, tolterodine, trospium, darifenacin, fesoterodine, and solifenacin. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-08-31

    Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia Neurology

    Key finding: Higher concentrations may reflect the intensity of the disease in FTD and are associated with more rapid atrophy of the frontal lobes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-08-30

    The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

    ✓ Peer-reviewed Treatments Nature

    Key finding: Aducanumab is a human monoclonal antibody that selectively targets aggregated Aβ. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-08-29

    A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: PSMD is a new, fully automated, and robust imaging marker for SVD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-08-29

    The worldwide costs of dementia 2015 and comparisons with 2010

    ✓ Peer-reviewed How common it is Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Worldwide costs of dementia are enormous and still inequitably distributed.

    Full summary, score breakdown and related studies → Original source

  7. 2016-08-28

    From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease

    ✓ Peer-reviewed Disease mechanisms The Journal of physiology

    Key finding: Over a century ago, the focal infection theory implicated these infections in the aetiology of several systemic diseases, ranging from arthritis to neurodegenerative diseases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-08-28

    Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies

    ✓ Peer-reviewed Tau biomarkers Annals of clinical and translational neurology

    Key finding: This assay can detect alpha-synuclein aggregation in Dementia with Lewy bodies and Parkinson's disease cerebrospinal fluid with sensitivities of 92% and 95%, respectively, and with an overall specificity of 100% when compared to Alzheimer and control cerebrospinal fluid. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-08-27

    Geographical Variation in Antipsychotic Drug Use in Elderly Patients with Dementia: A Nationwide Study

    ✓ Peer-reviewed Risk factors Journal of Alzheimer s Disease

    Key finding: In 2012, the national prevalence of antipsychotic drug use was 20.7% for elderly patients with dementia, with a national incidence of 3.9%. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-08-26

    Alzheimer's disease and gut microbiota

    ✓ Peer-reviewed Disease mechanisms Science China. Life sciences

    Key finding: All the results suggest that AD may begin in the gut, and is closely related to the imbalance of gut microbiota.

    Full summary, score breakdown and related studies → Original source

  11. 2016-08-26

    Towards understanding brain-gut-microbiome connections in Alzheimer's disease

    ✓ Peer-reviewed Risk factors BMC systems biology

    Key finding: Employing an integrated computational approach, we provide intriguing and supporting evidence for a role of microbial metabolites, an important modifiable environmental factor, in AD etiology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-08-26

    Aphasic variant of Alzheimer disease: Clinical, anatomic, and genetic features

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: There is a close, but not obligatory, association between logopenic PPA and AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →