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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,326–13,350 of 27,380 studies, newest first · page 534 of 1096.

January 2019 25

  1. 2019-01-01

    Airborne Magnetite- and Iron-Rich Pollution Nanoparticles: Potential Neurotoxicants and Environmental Risk Factors for Neurodegenerative Disease, Including Alzheimer's Disease

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: These magnetite particles range from ∼10 to 150 nm in size, and are often associated with other, non-endogenous metals (including platinum, cadmium, cerium).

    Full summary, score breakdown and related studies → Original source

  2. 2019-01-01

    Air Pollution and Dementia: A Systematic Review

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Evidence is emerging that greater exposure to airborne pollutants is associated with increased risk of dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2019-01-01

    A Systematic Review of Meta-Analyses that Evaluate Risk Factors for Dementia to Evaluate the Quantity, Quality, and Global Representativeness of Evidence

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: There is a lack of midlife specific data, limited data on VaD, and a lack of geographical representation for many risk factors for dementia.

    Full summary, score breakdown and related studies → Original source

  4. 2019-01-01

    Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: Scientific evidence collected over the past 4 decades suggests that a loss of cholinergic innervation in the cerebral cortex of patients with Alzheimer's disease is an early pathogenic event correlated with cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-01-01

    Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Aging

    Key finding: Our data suggests that down regulation of mTOR signaling, leading to enhanced autophagy and lysosomal clearance of Aβ fibrils, underlies the beneficial effects of geniposide against neuropathological damage and cognitive deficits characteristic of AD.

    Full summary, score breakdown and related studies → Original source

  6. 2019-01-01

    A Pilot Study of Exenatide Actions in Alzheimer's Disease

    ✓ Peer-reviewed Drug development Current Alzheimer research

    Key finding: The positive finding of lower EV Aβ42 supports emerging evidence that plasma neuronal EVs provide an effective platform for demonstrating biomarker responses in clinical trials in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-01-01

    Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Science translational medicine

    Key finding: After adjusting for multiple covariates such as age and sex, we found that NREM SWA showed an inverse relationship with AD pathology, particularly tauopathy, and that this association was most evident at the lowest frequencies of NREM SWA. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2019-01-01

    Ultrasensitive Detection of Plasma Amyloid-β as a Biomarker for Cognitively Normal Elderly Individuals at Risk of Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Plasma Aβ ratios in this study are a potential biomarker for brain Aβ deposition and therefore, for preclinical AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-01-01

    Midlife Hypertension and Alzheimer's Disease: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Vascular contributions Journal of Alzheimer's disease : JAD

    Key finding: Our study found that midlife stage 1 and stage 2 systolic hypertension is associated with increased risk of AD by 18 and 25%, respectively, although no association was found for diastolic hypertension. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-01-01

    Amyloid-β and Tau at the Crossroads of Alzheimer's Disease

    ✓ Peer-reviewed Clinical safety Advances in experimental medicine and biology

    Key finding: Alzheimer's disease (AD) is the most common form of dementia characterized neuropathologically by senile plaques and neurofibrillary tangles (NFTs). +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-01-01

    Immediate improvement of speech-in-noise perception through multisensory stimulation via an auditory to tactile sensory substitution

    ✓ Peer-reviewed Prevention trials Restorative neurology and neuroscience

    Key finding: These results are especially relevant when compared to previous SSD studies showing effects in behavior only after a demanding cognitive training. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-01-01

    Dietary Patterns and Cognitive Decline: key features for prevention

    ✓ Peer-reviewed Prevention trials Current pharmaceutical design

    Key finding: The decline in cognitive function is generally the result of the complex interaction of several factors. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2019-01-01

    A computer-based cognitive training in Mild Cognitive Impairment in Parkinson's Disease

    ✓ Peer-reviewed Prevention trials NeuroRehabilitation

    Key finding: Patients trained with CoRe showed a better evolution of cognitive decline, while untreated patients tended to get worse over time. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2019-01-01

    Neuropsychology of aging

    ✓ Peer-reviewed Prevention trials Handbook of clinical neurology

    Key finding: Yet, significant individual differences exist in this regard.

    Full summary, score breakdown and related studies → Original source

  15. 2019-01-01

    Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke

    ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease

    Key finding: High adherence to the MIND diet was associated with a slower rate of cognitive decline after stroke. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2019-01-01

    Is Alzheimer's Disease Risk Modifiable?

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: Remarkably, several large population-based longitudinal epidemiological studies have recently indicated that the incidence and prevalence of dementia might be decreasing in Western countries. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2019-01-01

    Biomarkers for Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Current Alzheimer research

    Key finding: Some proposed AD biomarkers include the detection of pathophysiological processes in the brain in vivo with new imaging techniques and novel PET ligands, and the determination of pathogenic proteins in cerebrospinal fluid showing anomalous levels of hyperphosphorylated tau and low Aβ peptide. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-01-01

    Mechanisms of Cell-to-Cell Transmission of Pathological Tau: A Review

    ✓ Peer-reviewed Disease mechanisms JAMA neurology

    Key finding: These findings provide compelling evidence that misfolded or pathological conformers of tau undergo cell-to-cell spread in a tauopathy strain-specific manner. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2019-01-01

    NF-κB as a Key Mediator of Brain Inflammation in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system CNS & neurological disorders drug targets

    Key finding: Long-term use of non-steroidal anti-inflammatory drugs prevents progression of AD and delays its onset, suggesting that there is a close correlation between NF-κB and AD pathogenesis.

    Full summary, score breakdown and related studies → Original source

  20. 2019 no date recorded — placed by publication year

    TRENDS IN OPIOID USE IN LONG-TERM CARE NURSING HOME RESIDENTS WITH DEMENTIA

    ✓ Peer-reviewed Health systems and care delivery Innovation in Aging

    Key finding: Opioid use was significantly higher in females and Whites and varied by states. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-01-01

    Brain-Gut-Microbiota Axis in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of neurogastroenterology and motility

    Key finding: Alzheimer's disease (AD) is the most frequent cause of dementia characterized by a progressive decline in cognitive function associated with the formation of amyloid beta (Aβ) plaques and neurofibrillary tangles. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-01-01

    Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Neuroscience

    Key finding: However, under pathological conditions, upregulation of death receptor family ligands, such as tumour necrosis factor (TNF), can sensitize cells in the CNS to apoptosis and a form of regulated necrotic cell death known as necroptosis that is mediated by receptor-interacting protein kinase 1 (RIPK1), RIPK3 and mixed lineage kinase domain-like protein (MLKL). +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-01-01

    Application of the NIA-AA Research Framework: Towards a Biological Definition of Alzheimer's Disease Using Cerebrospinal Fluid Biomarkers in the AIBL Study

    ✓ Peer-reviewed Tau biomarkers The journal of prevention of Alzheimer's disease

    Key finding: The National Institute on Aging and Alzheimer's Association (NIA-AA) have proposed a new Research Framework: Towards a biological definition of Alzheimer's disease, which uses a three-biomarker construct: Aß-amyloid, tau and neurodegeneration AT(N), to generate a biomarker based definition of Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-01-01

    TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD

    Key finding: The aim of our systematic review and meta-analysis was to investigate the role of TREM2 variants in neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-01-01

    High Systolic Blood Pressure Induces Cerebral Microvascular Endothelial Dysfunction, Neurovascular Unit Damage, and Cognitive Decline in Mice

    ✓ Peer-reviewed Risk genes beyond APOE Hypertension (Dallas, Tex. : 1979)

    Key finding: We hypothesized that a chronic elevation of PP would cause brain microvascular endothelial mechanical stress, damage the neurovascular unit, and ultimately induce cognitive impairment in mice, potentially contributing to the progression of vascular dementia and Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →