Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 25,726–25,750 of 27,380 studies, newest first · page 1030 of 1096.
June 1999 18
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1999-06-01
Norms for letter and category fluency: demographic corrections for age, education, and ethnicity
45/100 ✓ Peer-reviewed Risk factors Assessment
Key finding: Together, age, education, and ethnicity were significant predictors of letter and category fluency performance, accounting for 15% and 25% of variance, respectively.
Full summary, score breakdown and related studies → Original source
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1999-06-01
Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration
36/100 ✓ Peer-reviewed Drug development FEBS letters
Key finding: In support of this view, several studies have demonstrated that the treatment of cultured neurons with A beta leads to the hyperphosphorylation of tau protein and neuronal cell death. +2 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data
36/100 ✓ Peer-reviewed Vascular contributions Neuropharmacology
Key finding: This has unfortunately led to the conclusion that NMDA receptor antagonism is not a valid therapeutic approach. +4 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
36/100 ✓ Peer-reviewed Hippocampus size on brain scans The Journal of neuroscience : the official journal of the Society for Neuroscience
Key finding: This study takes advantage of continuing advances in the precision of magnetic resonance imaging (MRI) to quantify hippocampal volumes in a series of human subjects with a history of depression compared with controls. +4 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
Translating cell biology into therapeutic advances in Alzheimer's disease
41/100 ✓ Peer-reviewed Disease mechanisms Nature
Key finding: Studies of the molecular basis of Alzheimer's disease exemplify the increasingly blurred distinction between basic and applied biomedical research. +2 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
A Proportional Hazards Model for the Subdistribution of a Competing Risk
52/100 ✓ Peer-reviewed How common it is Journal of the American Statistical Association
With explanatory covariates, the standard analysis for competing risks data involves modeling the cause-specific hazard functions via a proportional hazards assumption.
Full summary, score breakdown and related studies → Original source
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1999-06-01
The role of microglia and macrophages in the pathophysiology of the CNS
45/100 ✓ Peer-reviewed Inflammation and the immune system Progress in neurobiology
Key finding: Only a subtype, the perivascular microglia, are regularly replaced from the bone marrow in adult animals. +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
A stop-codon mutation in the BRI gene associated with familial British dementia
52/100 ✓ Peer-reviewed Brain tissue and pathology Nature
Key finding: Cerebral amyloid angiopathy, non-neuritic and perivascular plaques and neurofibrillary tangles are the predominant pathological lesions. +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
Medial temporal lobe atrophy and memory dysfunction as predictors for dementia in subjects with mild cognitive impairment
47/100 ✓ Peer-reviewed Mild cognitive impairment Journal of neurology
Key finding: All medial temporal lobe measures increased the accuracy of prediction compared with only the memory score, by reducing the number of false-negative classifications of dementia.
Full summary, score breakdown and related studies → Original source
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1999-06-01
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau
52/100 ✓ Peer-reviewed Lewy body dementia Journal of neuropathology and experimental neurology
Key finding: Two members of this family were affected. +4 more findings
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1999-06-01
Health care concerns and guidelines for adults with Down syndrome
41/100 ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics
Key finding: We report on significant medical problems of adults with DS (DS adults) residing in a British Columbia provincial residential center, Woodlands, over the 12-year period from 1981 through 1992. +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
Acetylcholine in mind: a neurotransmitter correlate of consciousness?
42/100 ✓ Peer-reviewed Risk factors Trends in neurosciences
Key finding: In degenerative diseases of the brain, alterations in consciousness are associated with regional deficits in the cholinergic system. +1 more finding
Full summary, score breakdown and related studies → Original source
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1999-06-01
Rates of dementia in three ethnoracial groups
49/100 ✓ Peer-reviewed How common it is International journal of geriatric psychiatry
Key finding: Planning for the wide range of services necessary for care of those suffering from dementia should take into account ethnoracial differences in rates. +2 more findings
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1999-06-01
Reducing caregiver burden: a randomized psychoeducational intervention for caregivers of persons with dementia
64/100 ✓ Peer-reviewed Caregiving The Gerontologist
Key finding: Repeated measures ANOVA was used to test for significant differences between the intervention and waiting list control groups over a 5-month period.
Full summary, score breakdown and related studies → Original source
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1999-06-01
The relation between funding by the National Institutes of Health and the burden of disease
54/100 ✓ Peer-reviewed Caregiving The New England journal of medicine
Key finding: There was no relation between the amount of NIH funding and the incidence, prevalence, or number of hospital days attributed to each condition or disease (P=0.82, P=0.23, and P=0.21, respectively). +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-06-01
[Revalidation and standardization of the cognition mini-exam (first Spanish version of the Mini-Mental Status Examination) in the general geriatric population]
50/100 ✓ Peer-reviewed Getting a diagnosis Medicina clinica
Key finding: The validity of MEC is confirmed in the elderly population, with the same cut-off points recommended in the original standardization. +1 more finding
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1999-06-01
Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease
51/100 ✓ Peer-reviewed Getting a diagnosis Archives of neurology
Key finding: The sensitivity of CSF-beta-amyloid(1-42) level as a diagnostic marker for AD is high. +1 more finding
Full summary, score breakdown and related studies → Original source
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1999-06-01
Huperzine-A in capsules and tablets for treating patients with Alzheimer disease
46/100 ✓ Peer-reviewed Treatments Zhongguo yao li xue bao = Acta pharmacologica Sinica
Key finding: There is equal efficacy and safety between Hup in capsule and tablet for treating patients with AD, and Hup can reduce the pathological changes of the oxygen free radicals in the plasma and erythrocytes of patients with AD.
Full summary, score breakdown and related studies → Original source
May 1999 7
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1999-05-11
Guide to Preventive Cardiology for Women
57/100 ✓ Peer-reviewed Prevention and risk Circulation
C oronary heart disease (CHD) is the single leading cause of death and a significant cause of morbidity among American women. 1 Risk factors for CHD in women are well documented. 2 Compelling data from epidemiological studies and randomized clinical trials show that CHD is largely preventable.
Full summary, score breakdown and related studies → Original source
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1999-05-01
Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study
40/100 ✓ Peer-reviewed Prevention and risk PubMed
Key finding: At baseline, 211 (3.6%) of the women had 6 or more depressive symptoms. +4 more findings
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1999-05-01
Medicinal Plants and Alzheimer's Disease: from Ethnobotany to Phytotherapy
40/100 ✓ Peer-reviewed Treatments Journal of Pharmacy and Pharmacology
Key finding: Old European reference books, such as those on medicinal herbs, document a variety of other plants such as Salvia officinalis (sage) and Melissa officinalis (balm) with memory-improving properties, and cholinergic activities have recently been identified in extracts of these plants. +4 more findings
Full summary, score breakdown and related studies → Original source
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1999-05-01
Age-related metabolite changes and volume loss in the hippocampus by magnetic resonance spectroscopy and imaging
40/100 ✓ Peer-reviewed Hippocampus size on brain scans Neurobiology of aging
Key finding: Magnetic resonance imaging (MRI) studies have produced controversial results concerning the correlation of hippocampal volume loss with increasing age. +1 more finding
Full summary, score breakdown and related studies → Original source
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1999-05-01
A.E. Bennett Research Award. Developmental traumatology. Part II: Brain development
36/100 ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry
Key finding: These data suggest that the overwhelming stress of maltreatment experiences in childhood is associated with adverse brain development. +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-05-01
Hospitalization and Alzheimer's disease: results from a community-based study
43/100 ✓ Peer-reviewed End-of-life care The journals of gerontology. Series A, Biological sciences and medical sciences
Key finding: In this community-based cohort, subjects with severe AD were more likely to be hospitalized than unaffected subjects. +3 more findings
Full summary, score breakdown and related studies → Original source
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1999-05-01
High monounsaturated fatty acids intake protects against age-related cognitive decline
69/100 ✓ Peer-reviewed Prevention trials Neurology
Key finding: In an elderly population of Southern Italy with a typical Mediterranean diet, high MUFA intakes appeared to be protective against age-related cognitive decline. +1 more finding
Full summary, score breakdown and related studies → Original source
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