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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,576–12,600 of 27,380 studies, newest first · page 504 of 1096.

August 2019 25

  1. 2019-08-08

    Fine particulate matter is a potential determinant of Alzheimer's disease: A systemic review and meta-analysis

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: After exclusion of all irrelevant studies, we analyzed the results of four cohort studies conducted in Canada, Taiwan, the UK, and the US during 2015-2018 among more than 12 million elderly subjects aged ≥50 years (N = 12,119,853). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-08-07

    Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics

    ✓ Peer-reviewed Genetics Brain

    Key finding: Here, we correlated brain imaging phenotypes from ∼9000 UK Biobank participants with handedness, and with loci found significantly associated with handedness after we performed genome-wide association studies (GWAS) in ∼400 000 of these participants. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-08-07

    Graphic designed bedroom doors to support dementia wandering in residential care homes: Innovative practice

    ✓ Peer-reviewed Health systems and care delivery Dementia (London, England)

    Key finding: The post-intervention data demonstrated that there was a reduction in persistent walking, eloping behaviours and spatial disorientation.

    Full summary, score breakdown and related studies → Original source

  4. 2019-08-07

    Disease-modifying therapy for proteinopathies: Can the exception become the rule?

    ✓ Peer-reviewed Drug development Progress in molecular biology and translational science

    Key finding: Disease-modifying therapies for proteinopathies are urgently needed yet clinical trials for the major neurodegenerative diseases, Alzheimer's and Parkinson's, have been failing at an alarming rate leaving patients and caregivers scrambling for any sign of hope. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-08-07

    A pathogenic PSEN1 Trp165Cys mutation associated with early-onset Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE BMC neurology

    Key finding: We report a case of EOAD having a pathogenic PSEN1 (Trp165Cys) confirmed with in silico and in vitro predictions.

    Full summary, score breakdown and related studies → Original source

  6. 2019-08-07

    A novel V272D presenilin mutation associated with logopenia, disorientation, and apraxia in an autosomal-dominant Alzheimer's disease family

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: In the present study, a novel mutation in the presenilin 1 gene was discovered in an Iraq-native patient with early-onset Alzheimer's disease, who presented with speech impairment and memory decline at age 46 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-08-07

    Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study

    ✓ Peer-reviewed Prevention and risk BMJ (Clinical research ed.)

    Key finding: Adherence to the Life Simple 7 ideal cardiovascular health recommendations in midlife was associated with a lower risk of dementia later in life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-08-05

    Identification of AV-1451 as a Weak, Nonselective Inhibitor of Monoamine Oxidase

    ✓ Peer-reviewed Brain scans and imaging ACS chemical neuroscience

    Key finding: While the radiotracer binds with high affinity to tau neurofibrillary tangles, extensive clinical studies have simultaneously revealed off-target tracer accumulation in areas of low tau burden such as the basal ganglia and choroid plexus.

    Full summary, score breakdown and related studies → Original source

  9. 2019-08-05

    Cognitive dysfunction: A growing link between diabetes and Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Drug development research

    Key finding: Diabetes is associated with various complications like nephropathy, neuropathy, retinopathy, diabetic foot, cognitive impairment, and many more. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-08-05

    Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice

    ✓ Peer-reviewed Inflammation and the immune system Translational psychiatry

    Key finding: Treatment for AD is still a difficult task in clinic. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-08-05

    Mechanisms and treatment of late-life depression

    ✓ Peer-reviewed Prevention and risk Translational psychiatry

    Key finding: Significant progress has been made in neurostimulation treatments in depressed younger adults. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2019-08-02

    Sex-Specific Differences in End-of-Life Burdensome Interventions and Antibiotic Therapy in Nursing Home Residents With Advanced Dementia

    ✓ Peer-reviewed End-of-life care JAMA network open

    Key finding: The final cohort included 27 243 nursing home residents with advanced dementia (19 363 [71.1%] women) who died between June 1, 2010, and March 31, 2015, at the median (interquartile range) age of 88 (83-92) years. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-08-02

    Can Persons with Dementia Meaningfully Participate in Advance Care Planning Discussions? A Mixed-Methods Study of SPIRIT

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: All 23 were able to articulate their end-of-life wishes very or somewhat coherently during the SPIRIT session; of those, 14 PWDs had moderate dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-08-02

    The Effect of Cochlear Implants on Cognitive Function in Older Adults: Initial Baseline and 18-Month Follow Up Results for a Prospective International Longitudinal Study

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: In older adults, hearing loss is independently associated with an increased rate of cognitive decline, and has been identified to be a modifiable risk factor for dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-08-02

    Sleep Duration and Sleep Quality in Caregivers of Patients With Dementia: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Caregiving JAMA network open

    Key finding: Thirty-five studies were analyzed with data from 3268 caregivers (pooled mean age [SD of sample means], 63.48 [5.99] years; 76.7% female) were analyzed. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-08-02

    The neuropathological diagnosis of Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Molecular neurodegeneration

    Key finding: Alzheimer's disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are increasingly recognized. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2019-08-02

    Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study

    ✓ Peer-reviewed Prevention and risk PLoS Medicine

    Key finding: More frequent social contact at age 60 years was associated with lower dementia risk (hazard ratio [HR] for each SD higher social contact frequency = 0.88 [95% CI 0.79, 0.98], p = 0.02); effect size of the association of social contact at 50 or 70 years with dementia was similar (0.92 [95% CI 0.83, 1.02], p = 0.13 and 0.91 [95% CI 0.78, 1.06], p = 0.23, respectively) but not statistically significant. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-08-01

    Cost of dementia in Medicare managed care: a systematic literature review

    ✓ Peer-reviewed Costs and economics The American journal of managed care

    Key finding: Despite the growth in Medicare managed care enrollment, only 9 papers report the costs of care for individuals with ADRD within these plans, and only 1 study reports data less than 10 years old. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2019-08 month only

    [Antisense therapies for neurological diseases]

    ✓ Peer-reviewed Drug development Der Nervenarzt

    Key finding: Perhaps the most significant advantage of ASO therapeutics over other small molecule approaches is that acquisition of the target sequence provides immediate knowledge of possible complementary oligonucleotide therapeutics.

    Full summary, score breakdown and related studies → Original source

  20. 2019-08 month only

    [Optical coherence tomography angiography in neuronal diseases : Preliminary findings]

    ✓ Peer-reviewed Brain scans and imaging Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft

    Key finding: It could be shown that Alzheimer type dementia, Parkinson's disease, multiple sclerosis. cerebral infarction and CADASIL are neuronal diseases with rarification of retinal vessels and atrophy of the retinal layers in the ocular fundus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2019-08-01

    Genes and genetics in hyperhomocysteinemia and the "1-carbon metabolism": implications for retinal structure and eye functions

    ✓ Peer-reviewed Brain scans and imaging Canadian journal of physiology and pharmacology

    Key finding: Elevated levels of Hcy known as hyperhomocysteinemia (HHcy) results from vitamin B deficiency, lack of exercise, smoking, excessive alcohol intake, high-fat and methionine-rich diet, and the underlying genetic defects.

    Full summary, score breakdown and related studies → Original source

  22. 2019-08-01

    Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy

    ✓ Peer-reviewed Brain scans and imaging Cell reports

    Key finding: These results demonstrate that complement activation contributes to neurodegeneration caused by tau pathology and suggest that blocking C3 function might be protective in AD and other tauopathies.

    Full summary, score breakdown and related studies → Original source

  23. 2019-08-01

    A systematic review and meta-analysis of the prevalence and associations of stress and burnout among staff in long-term care facilities for people with dementia

    ✓ Peer-reviewed Caregiving International psychogeriatrics

    Key finding: Most care staff for long-term care residents with dementia experience low or moderate burnout levels. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-08-01

    A Pilot Double-Blind Randomized Controlled Trial of Cognitive Training Combined with Transcranial Direct Current Stimulation for Amnestic Mild Cognitive Impairment

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: This study found that CT+Active tDCS did not produce greater memory improvement compared to CT+Sham tDCS. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-08-01

    AgeWell.de - study protocol of a pragmatic multi-center cluster-randomized controlled prevention trial against cognitive decline in older primary care patients

    ✓ Peer-reviewed Prevention trials BMC geriatrics

    Key finding: So far, however, only few such multi-component trials have been launched, but yielding promising results. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →