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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,701–25,725 of 27,380 studies, newest first · page 1029 of 1096.

July 1999 24

  1. 1999-07-15

    α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins

    ✓ Peer-reviewed Brain tissue and pathology Journal of Neuroscience

    Key finding: The association of alpha-synuclein with BAD and inhibition of protein kinase C suggests that increased expression of alpha-synuclein could be harmful. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-07-01

    A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer’s disease

    ✓ Peer-reviewed Clinical trials Neurology

    Key finding: There were no group differences with any of the outcome measures in an intent-to-treat analysis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-07-01

    Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a ‘thrifty’ allele?

    ✓ Peer-reviewed Genetics Annals of Human Genetics

    Key finding: We suggest that the APOE*4, based on some functional properties it has and on its distribution among human populations, could be identified as a 'thrifty' allele.

    Full summary, score breakdown and related studies → Original source

  4. 1999-07 month only

    Functional characterization of apolipoprotein E isoforms overexpressed in Escherichia coli

    ✓ Peer-reviewed Genetics Protein expression and purification

    Key finding: Apolipoprotein (apo) E plays an important role in lipid metabolism, and the major isoforms of apoE (apoE2, apoE3, and apoE4) have significantly different metabolic effects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-07-01

    Bright light therapy: improved sensitivity to its effects on rest-activity rhythms in Alzheimer patients by application of nonparametric methods

    ✓ Peer-reviewed Risk factors Chronobiology international

    Key finding: It was demonstrated that the light-induced improvement in coupling of the rest-activity rhythm to the environmental zeitgeber of bright light is better detected using nonparametric procedures.

    Full summary, score breakdown and related studies → Original source

  6. 1999-07-01

    Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease

    ✓ Peer-reviewed Vascular contributions The American journal of psychiatry

    Key finding: Delusional misidentification and hallucinations in the early stages of dementia may improve differentiation between patients with dementia with Lewy bodies and those with Alzheimer's disease and have important treatment implications. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1999-07-01

    Anxiety of Alzheimer's disease: prevalence, and comorbidity

    ✓ Peer-reviewed Clinical safety The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Anxiety symptoms were common and significantly related to ADL and additional neuropsychiatric problems in this sample. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-07-01

    A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Recently intronic and exonic mutations in the Tau gene have been found to be associated with familial neurodegenerative syndromes characterized not only by a predominantly frontotemporal dementia but also by the presence of neurological signs consistent with the dysfunction of multiple subcortical neuronal circuitries. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1999-07-01

    Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences of the United States of America

    Key finding: In addition to CD4, different gp120 isolates bind to the alpha- or beta-chemokine receptors CXCR4 and CCR5, respectively. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-07-01

    Norms for the Mini-Mental State Examination in a healthy population

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Although the Mini-Mental State Examination (MMSE) is widely used in clinical practice, few norms exist for healthy populations covering a broad range of ages. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1999-07-01

    Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Familial forms of the disease have been linked to mutations in the amyloid precursor protein (APP) and the presenilin genes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1999-07-01

    alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

    ✓ Peer-reviewed Lewy body dementia The Journal of biological chemistry

    Key finding: These results suggest that differences in aggregation kinetics of alpha-synucleins cannot be explained by differences in solubility but are due to different nucleation rates.

    Full summary, score breakdown and related studies → Original source

  13. 1999-07-01

    APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: In participants with no epsilon4 alleles, the age-specific prevalence of AD reached a maximum and then declined after age 95. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 1999-07-01

    Motor neuron disease-inclusion dementia presenting as cortical-basal ganglionic degeneration

    ✓ Peer-reviewed Digital health tools Movement disorders : official journal of the Movement Disorder Society

    Key finding: The frontotemporal dementias are a group of relatively new and evolving clinical and pathologic entities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 1999-07-01

    The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons

    ✓ Peer-reviewed How common it is JAMA

    Key finding: Most healthy elderly people did not experience cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 1999-07-01

    A high plasma concentration of TNF-alpha is associated with dementia in centenarians

    ✓ Peer-reviewed How common it is The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: This study demonstrates that, even in apparently healthy subjects, age-associated immune activation indicated by raised levels of pro-inflammatory cytokines may reflect age-associated pathological processes that develop over decades.

    Full summary, score breakdown and related studies → Original source

  17. 1999-07-01

    Predictors of mortality in patients with Alzheimer's disease living in nursing homes

    ✓ Peer-reviewed Disparities Journal of neurology, neurosurgery, and psychiatry

    Key finding: Age, sex, functional limitation, and malnutrition seem to be the strongest predictors of death for patients with Alzheimer's disease in nursing homes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 1999-07-01

    Drug-induced cognitive impairment in the elderly

    ✓ Peer-reviewed Getting a diagnosis Drugs & aging

    Key finding: Elderly people are more likely than younger patients to develop cognitive impairment as a result of taking medications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 1999-07-01

    Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

    ✓ Peer-reviewed Getting a diagnosis AIDS (London, England)

    Key finding: A proportional increase in ADC compared with other ADIs and a marked increase in the median CD4 cell count at ADC diagnosis have occurred since the introduction of HAART in Australia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 1999-07-01

    White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer's disease, vascular dementia, and normal aging

    ✓ Peer-reviewed Getting a diagnosis Journal of neurology, neurosurgery, and psychiatry

    Key finding: In common with Alzheimer's disease and vascular dementia, PVHs and WMHs were significantly more extensive in dementia with Lewy bodies than in controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 1999-07-01

    A randomized, controlled trial of bright light therapy for agitated behaviors in dementia patients residing in long-term care

    ✓ Peer-reviewed Treatments International journal of geriatric psychiatry

    Key finding: Eight out of 15 patients completed the entire study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 1999-07-01

    APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The epsilon2 allele confers a protective effect, and women with DS have an increased risk for AD, as in the general population. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 1999-07-01

    The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: Cerebral amyloid angiopathy (CAA) is associated with apolipoprotein E (APOE gene, apoE protein) polymorphism: current evidence suggests that the epsilon4 allele is a risk factor for the development of CAA and the epsilon2 allele predisposes to hemorrhage. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 1999-07-01

    The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: We consider how the schedule of AD may have evolved in early humans in relation to the apolipoprotein E (apoE) allele system, which is not found in other primates, and to the increasing duration of postnatal care. +4 more findings

    Full summary, score breakdown and related studies → Original source

June 1999 1

  1. 1999-06-01

    The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction

    ✓ Peer-reviewed Brain tissue and pathology Biochemistry

    Key finding: These findings indicate that the accumulation of A beta could be a direct source of oxidative stress in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

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