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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,276–19,300 of 27,380 studies, newest first · page 772 of 1096.

August 2012 25

  1. 2012-08-20

    Effect of acupuncture in mild cognitive impairment and Alzheimer disease: a functional MRI study

    ✓ Peer-reviewed Brain scans and imaging PloS one

    Key finding: We found that during the resting state, brain activities in AD and MCI patients were different from those of control subjects. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-08-18

    Metabolic syndrome, mild cognitive impairment and Alzheimer's disease--the emerging role of systemic low-grade inflammation and adiposity

    ✓ Peer-reviewed Mild cognitive impairment Brain research bulletin

    Key finding: Despite the positive results of several epidemiological studies, the exact mechanisms underlying the connection between MetS and AD remain uncertain and various theories are being assessed.

    Full summary, score breakdown and related studies → Original source

  3. 2012-08-17

    Online games training aging brains: limited transfer to cognitive control functions

    ✓ Peer-reviewed Prevention trials Frontiers in human neuroscience

    Key finding: Compared with the documentary group, the game group showed larger improvement of inhibition (Stop-Signal task) and inductive reasoning (Raven-SPM), whereas the documentary group showed more improvement in selective attention (UFoV-3).

    Full summary, score breakdown and related studies → Original source

  4. 2012-08-16

    Organochlorine pesticide levels and risk of Alzheimer’s disease in north Indian population

    ✓ Peer-reviewed Risk factors Human & Experimental Toxicology

    Key finding: Alzheimer's disease (AD) could result from a multifactorial process involving both genetic predisposition and exposure to environmental factors like pesticides. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-08-16

    Activity dependent degeneration explains hub vulnerability in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging PLoS computational biology

    Key finding: Brain connectivity studies have revealed that highly connected 'hub' regions are particularly vulnerable to Alzheimer pathology: they show marked amyloid-β deposition at an early stage. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-08-15

    Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice

    ✓ Peer-reviewed Drug development Age (Dordrecht, Netherlands)

    Key finding: Prior studies of the long-acting GLP-1 receptor agonist, exendin-4 (Ex-4), an incretin mimetic approved for type 2 diabetes mellitus treatment, demonstrated its neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases, and, consequent to commonalities in mechanisms underpinning these disorders, Ex-4 was assessed in a mouse mTBI model. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2012-08-15

    Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2

    ✓ Peer-reviewed Disease mechanisms PloS one

    Key finding: Our observations provide a necessary and timely insight into cellular mechanisms that underlie the initial pathological events that lead to synaptic dysfunction in Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-08-15

    A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

    ✓ Peer-reviewed Disease mechanisms Science Translational Medicine

    Because it lacks a lymphatic circulation, the brain must clear extracellular proteins by an alternative mechanism.

    Full summary, score breakdown and related studies → Original source

  9. 2012-08-15

    Characterizing dementia with Lewy bodies by means of diffusion tensor imaging

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Despite a similar level of dementia severity, patterns of DTI changes in AD and DLB differed significantly. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-08-14

    Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

    ✓ Peer-reviewed Prevention trials Molecular psychiatry

    Key finding: The objective of this study was to determine if plasma Aβ and amyloid brain deposition are associated with physical activity levels, and whether these associations differed between carriers and non-carriers of the apolipoprotein E (APOE) ε4 allele. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-08-14

    Gene expression profiling in human neurodegenerative disease

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Neurology

    Key finding: Increasing scientific rigour and improved analytical tools have led to more-reproducible data. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-08-14

    Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE The EMBO journal

    Key finding: We recently showed that presenilin-1 and -2, the catalytic components of γ-secretase, and γ-secretase activity itself, are highly enriched in a subcompartment of the endoplasmic reticulum (ER) that is physically and biochemically connected to mitochondria, called mitochondria-associated ER membranes (MAMs). +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-08-13

    GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease

    ✓ Peer-reviewed Biomarkers PloS one

    Key finding: In conclusion, GFAPδ protein is present in SVZ, RMS, and neurogenic astrocytes of the SGZ, but also outside neurogenic niches.

    Full summary, score breakdown and related studies → Original source

  14. 2012-08-10

    Palliative care services for people with dementia: a synthesis of the literature reporting the views and experiences of professionals and family carers

    ✓ Peer-reviewed End-of-life care Dementia (London, England)

    Key finding: This is a synthesis of the concerns and challenges for carers at the end of life. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-08-09

    Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy

    ✓ Peer-reviewed Disease mechanisms Autophagy

    Key finding: The improvement of MAPT pathology is associated with increased nerve cell survival.

    Full summary, score breakdown and related studies → Original source

  16. 2012-08-09

    The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Therefore, to understand the processing of the amyloid precursor protein (APP) is of critical importance. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2012-08-09

    Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study

    ✓ Peer-reviewed How common it is Brain : a journal of neurology

    Key finding: Recent studies suggest that delirium is associated with risk of dementia and also acceleration of decline in existing dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2012-08-09

    Epidemiology of dementia in Asia: insights on prevalence, trends and novel risk factors

    ✓ Peer-reviewed Disparities Journal of the neurological sciences

    Key finding: Overall dementia prevalence is expected to rise dramatically across Asia due to maturing populations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2012-08-08

    Cognitive enhancement by pharmacological and behavioral interventions: the murine Down syndrome model

    ✓ Peer-reviewed Down syndrome and Alzheimer's Biochemical pharmacology

    Key finding: Most remarkably, the improved cognitive performance of Ts65Dn can persist for weeks and months after cessation of drug treatment, as demonstrated for the non-specific GABA antagonist pentylenetetrazole.

    Full summary, score breakdown and related studies → Original source

  20. 2012-08-08

    Microbleeds do not affect rate of cognitive decline in Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: MBs did not influence the rate of cognitive decline in patients with AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2012-08-07

    How do persons with dementia participate in decision making related to health and daily care? a multi-case study

    ✓ Peer-reviewed End-of-life care BMC health services research

    Key finding: Persons with moderate dementia demonstrated variability in how they participated in decision making. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-08-06

    Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Perturbations of brain network activity are observed in AD patients and in conditions that increase the risk of developing AD, suggesting that aberrant network activity might contribute to AD-related cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2012-08-04

    The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system

    ✓ Peer-reviewed Disease mechanisms The American journal of pathology

    Key finding: We found that, in addition to its well-described axonal localization, normal tau is present at both presynaptic and postsynaptic terminals in control human brains. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-08-03

    At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response

    ✓ Peer-reviewed Clinical safety Brain, behavior, and immunity

    Key finding: Delirium affects around one in eight hospital inpatients and is associated with multiple adverse consequences, including new institutionalisation, worsening of existing dementia, and death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-08-02

    Atrial fibrillation and the risk of incident dementia: a meta-analysis

    ✓ Peer-reviewed Vascular contributions Heart rhythm

    Key finding: AF is independently associated with increased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →