Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 15,526–15,550 of 27,380 studies, newest first · page 622 of 1096.
January 2017 25
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2017-01-01
Down syndrome, increased risk of dementia and lipid disturbances
30/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Developmental period medicine
Key finding: The "critical region" encompasses genes potentially associated with increase risk of dementia, e.g. the APP gene (amyloid beta precursor protein) which leads to excessive amyloid beta production. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease
33/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Current Alzheimer research
Key finding: The humble success of current therapeutic strategies along with the lack of basic knowledge of the brain disease mechanisms calls for alternatives that benefit patients in the present moment. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Feasibility of Lumbar Puncture in the Study of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Subjects with Down Syndrome
45/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease : JAD
Key finding: LP can be safely performed to study CSF biomarkers in DS.
Full summary, score breakdown and related studies → Original source
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2017-01-01
Relationships of Dietary Patterns, Foods, and Micro- and Macronutrients with Alzheimer's Disease and Late-Life Cognitive Disorders: A Systematic Review
60/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: In particular, higher adherence to a Mediterranean-type diet was associated with decreased cognitive decline. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
The Gut Microbiota and Alzheimer's Disease
50/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: AD, the most common form of dementia, is a neurodegenerative disorder associated with impaired cognition and cerebral accumulation of amyloid-β peptides (Aβ). +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Age and Graphomotor Decision Making Assessed with the Digital Clock Drawing Test: The Framingham Heart Study
43/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: Longer age-related decision making latencies may reflect a greater need for working memory and increased self-monitoring in older subjects.
Full summary, score breakdown and related studies → Original source
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2017-01-01
Prediction of Incipient Alzheimer's Disease Dementia in Patients with Mild Cognitive Impairment
47/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD
Key finding: The method presented in this paper can be used to separate stable MCI patients from those who are at early stages of AD dementia with high accuracy. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012
71/100 ✓ Peer-reviewed How common it is JAMA internal medicine
Key finding: The study cohorts had an average age of 75.0 years (95% CI, 74.8-75.2 years) in 2000 and 74.8 years (95% CI, 74.5-75.1 years) in 2012 (P = .24); 58.4% (95% CI, 57.3%-59.4%) of the 2000 cohort was female compared with 56.3% (95% CI, 55.5%-57.0%) of the 2012 cohort (P Conclusions and relevance The prevalence of dementia in the United States declined significantly between 2000 and 2012. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Dementia Prevalence in a Rural Region of South Africa: A Cross-Sectional Community Study
50/100 ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD
Key finding: Dementia prevalence estimates were higher than expected for this low-income rural community. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Association of Central Arterial Stiffness and Pressure Pulsatility with Mild Cognitive Impairment and Dementia: The Atherosclerosis Risk in Communities Study-Neurocognitive Study (ARIC-NCS)
51/100 ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD
Key finding: Higher arterial stiffness and pulsatility were associated with MCI and dementia in white participants. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Alzheimer's Disease in the Latino Community: Intersection of Genetics and Social Determinants of Health
46/100 ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD
Key finding: Therefore, AD has reached epidemic proportions with significant socioeconomic implications. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
The Utilization of Robotic Pets in Dementia Care
69/100 ✓ Peer-reviewed Caregiving Journal of Alzheimer's disease : JAD
Key finding: Treatment with the PARO robot decreased stress and anxiety in the treatment group and resulted in reductions in the use of psychoactive medications and pain medications in elderly clients with dementia. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Comorbidity and polypharmacy in people with dementia: insights from a large, population-based cross-sectional analysis of primary care data
59/100 ✓ Peer-reviewed Caregiving Age and ageing
Key finding: Such complex needs require an integrated response from general health professionals and multidisciplinary dementia specialists.
Full summary, score breakdown and related studies → Original source
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2017-01-01
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
68/100 ✓ Peer-reviewed Caregiving The Lancet. Neurology
Key finding: These samples were graded on an ordinal scale and genotyped for variants associated with synucleinopathies. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
56/100 ✓ Peer-reviewed Caregiving JAMA neurology
Key finding: In this study, altered AQP4 expression was associated with aging brains. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Prevalence of Depression in Patients With Mild Cognitive Impairment: A Systematic Review and Meta-analysis
73/100 ✓ Peer-reviewed Getting a diagnosis JAMA psychiatry
Key finding: Of 5687 unique abstracts, 255 were selected for full-text review, and 57 studies, representing 20 892 patients, met all inclusion criteria. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index
56/100 ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD
Key finding: LIBRA might be a useful tool to identify individuals for primary prevention interventions of dementia in midlife, and maybe in late life, but not in the oldest-old. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Alzheimer's Disease and Exercise: A Literature Review
42/100 ✓ Peer-reviewed Prevention and risk Current sports medicine reports
Key finding: It is the leading cause of dementia in late adult life and is associated with a significant social burden and increased morbidity and mortality in the elderly. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease
61/100 ✓ Peer-reviewed Prevention and risk JAMA neurology
Key finding: These findings suggest amyloid pathologies significantly influence white matter and that these abnormalities may signify an early feature of the disease process. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Update on Alzheimer's Disease Therapy and Prevention Strategies
49/100 ✓ Peer-reviewed Prevention and risk Annual review of medicine
Key finding: Significant investments in therapeutic drug discovery programs over the past two decades have yielded some important insights but no blockbuster drugs to alter the course of disease. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Effects of Risperidone and Galantamine Treatment on Alzheimer's Disease Biomarker Levels in Cerebrospinal Fluid
53/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: Our results suggest that risperidone may affect the CSF profile of AD biomarkers indicating more amyloid pathology. +4 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Alzheimer's Disease and Chinese Medicine as a Useful Alternative Intervention Tool: A Mini-Review
36/100 ✓ Peer-reviewed Treatments Current Alzheimer research
Key finding: The authors of this mini-review list the key benefits (e.g., positive results of the reviewed randomized clinical trials studies for the improvement of cognitive decline in AD) and limitations (e.g., low awareness of benefits of TCM in Europe) of Chinese medicine therapy for the treatment of AD. +1 more finding
Full summary, score breakdown and related studies → Original source
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2017-01-01
Do Hearing Aids Influence Behavioral and Psychological Symptoms of Dementia and Quality of Life in Hearing Impaired Alzheimer's Disease Patients and Their Caregivers?
60/100 ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD
Key finding: These findings do not provide evidence of improvement in behavioral symptoms, functional status, or QoL of hearing impaired AD patients and their caregivers after 6 months of HA use. +3 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Cognitive Changes with Omega-3 Polyunsaturated Fatty Acids in Non-Demented Older Adults with Low Omega-3 Index
66/100 ✓ Peer-reviewed Treatments The journal of nutrition, health & aging
Key finding: We found some evidence that n-3 PUFAs might be beneficial for the maintenance of executive functioning in older adults at risk of dementia with low omega-3 index, but this exploratory finding requires further confirmation. +2 more findings
Full summary, score breakdown and related studies → Original source
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2017-01-01
Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype
60/100 ✓ Peer-reviewed Genetics JAMA neurology
Key finding: Among the 183 study participants, mean (SD) age was 85.5 (3) years, 76 were women (41.5%), and 177 were white (96.7%). +3 more findings
Full summary, score breakdown and related studies → Original source
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