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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,726–11,750 of 27,380 studies, newest first · page 470 of 1096.

April 2020 25

  1. 2020-04-15

    Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature

    ✓ Peer-reviewed Risk factors Sleep

    Key finding: We found that tau phosphorylation undergoes sleep-driven circadian variations as it is hyperphosphorylated during sleep but not during acute sleep deprivation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-04-15

    MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous

    ✓ Peer-reviewed Brain scans and imaging Annals of clinical and translational neurology

    Key finding: For 50-59 greater medial temporal atrophy and flortaucipir uptake was observed in the typical compared with atypical phenotype. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-04-15

    Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Science advances

    Key finding: These results show that Aβ pathology may induce changes in soluble tau release and phosphorylation, which is followed by tau aggregation several years later in humans.

    Full summary, score breakdown and related studies → Original source

  4. 2020-04-15

    Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

    ✓ Peer-reviewed Prevention and risk Journal of clinical medicine

    Key finding: Current research has shown that (i) increased peripheral lactate levels (following high intensity exercise) are associated with increased peripheral BDNF levels, (ii) lactate infusion at rest can increase peripheral and central BDNF levels and (iii) lactate plays a very complex role in the brain's metabolism.

    Full summary, score breakdown and related studies → Original source

  5. 2020-04-14

    Improving the resistance and resilience framework for aging and dementia studies

    ✓ Peer-reviewed Risk factors Alzheimer's research & therapy

    Key finding: While the field advances towards consensus definitions of existing concepts, the resistance vs resilience terminology may provide clarity in the communication of results in aging and dementia studies as well as provide a framework for the development of both hypotheses and study designs.

    Full summary, score breakdown and related studies → Original source

  6. 2020-04-14

    Longitudinal evaluation of the natural history of amyloid-β in plasma and brain

    ✓ Peer-reviewed Biomarkers Brain communications

    Key finding: The trajectory of plasma amyloid-β preceded that of brain amyloid-β by a median value of 6 years (significant at 88% confidence interval). +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2020-04-14

    Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

    ✓ Peer-reviewed Vascular contributions Frontiers in aging neuroscience

    Key finding: Recently, however, a growing body of evidence has revealed that pericytes play various important roles: development and maintenance of blood-brain barrier (BBB), regulation of the neurovascular system (e.g., vascular stability, vessel formation, cerebral blood flow, etc.), trafficking of inflammatory cells, clearance of toxic waste products from the brain, and acquisition of stem cell-like properties.

    Full summary, score breakdown and related studies → Original source

  8. 2020-04-14

    Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia

    ✓ Peer-reviewed Clinical safety Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Future experiments and validation studies Future research should determine the extent to which prevention of surgery-induced microgliosis and/or neurovascular unit dysfunction can prevent or ameliorate postoperative memory and attention deficits in animal models. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-04-14

    Neuropsychiatric Symptoms in Mild Cognitive Impairment: A Literature Review

    ✓ Peer-reviewed Mild cognitive impairment Dementia and geriatric cognitive disorders

    Key finding: Late-onset NPS, even in a mild form (mild behavioural impairment) were found to be associated with an increased risk of dementia, even in the absence of cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-04-14

    Cortical microstructural correlates of astrocytosis in autosomal-dominant Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Our proof-of-concept study is the first to show that microstructural and macrostructural changes can reflect underlying neuroinflammatory mechanisms in early stages of Alzheimer disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2020-04-13

    Racial and Ethnic Differences in Knowledge About One's Dementia Status

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Among subjects identified as having dementia by the prediction model, 43.5% to 50.2%, depending on the survey year, reported that they were informed of the dementia status by their physician. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-04-13

    Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

    ✓ Peer-reviewed Tau biomarkers Nature medicine

    Key finding: A protein network module linked to sugar metabolism emerged as one of the modules most significantly associated with AD pathology and cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2020-04-13

    Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2

    ✓ Peer-reviewed Prevention trials Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Closer Mediterranean diet adherence was associated with lower risk of cognitive impairment but not slower decline in cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-04-12

    Quantitative amyloid PET in Alzheimer's disease: the AMYPAD prognostic and natural history study

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Primary include several amyloid PET measurements (Centiloid, SUVr, BPND , R1 ), and secondary are their changes from baseline, relationship to other amyloid markers (cerebrospinal fluid and visual assessment), and predictive value of AD-related decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2020-04-11

    Breaking Social Isolation Amidst COVID‐19: A Viewpoint on Improving Access to Technology in Long‐Term Care Facilities

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: In regards to policy-making decisions and resource allocation, the success of making technology more accessible to the marginalized older population should not be measured solely on the outcome of avoiding acute care services; its benefits should rather be assessed with functional health as the focus of intervention, including measures of psychophysical well-being and life satisfaction.9 Higher-end immersive technologies could be installed as a private expense in a patient's room; they could also be made available in common recreational areas within a leisure and/or fitness room, provided by the LTC facility through support of government subsidies and incentives aimed at promoting health of its aging population. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-04-10

    Dynamic changes of CSF sTREM2 in preclinical Alzheimer's disease: the CABLE study

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: Loss of function of triggering receptor expressed on myeloid cell 2 (TREM2), a key receptor selectively expressed by microglia in the brain, contributes to the development of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-04-09

    Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery

    ✓ Peer-reviewed Clinical safety Antioxidants & redox signaling

    Key finding: Accumulating evidence suggests that inflammation is a major contributor in the pathogenesis of several highly prevalent, but also rare, neurological diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2020-04-09

    Technologies for Cognitive Training and Cognitive Rehabilitation for People With Mild Cognitive Impairment and Dementia. A Systematic Review

    ✓ Peer-reviewed Mild cognitive impairment Frontiers in psychology

    Key finding: On the overall, the programs were aimed at people with different clinical conditions, able to create specific treatments and personalized training, optimized for portable devices, and user-friendly.

    Full summary, score breakdown and related studies → Original source

  19. 2020-04-09

    Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism

    ✓ Peer-reviewed Risk factors Journal of neurology, neurosurgery, and psychiatry

    Key finding: Increased α-synuclein egress in serum neuronal exosomes precedes the diagnosis of Parkinson's disease, persists with disease progression and in combination with clusterin predicts and differentiates Parkinson's disease from atypical parkinsonism. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2020-04-09

    The presubiculum links incipient amyloid and tau pathology to memory function in older persons

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: The presubiculum captures unique AD-related biological variation that is not reflected in total hippocampal volume. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2020-04-08

    Influence of the Mediterranean and Ketogenic Diets on Cognitive Status and Decline: A Narrative Review

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: A growing body of evidence has demonstrated that lifestyle habits and nutritional patterns could delay the natural course of the neurodegeneration process. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020-04-08

    Leveraging preclinical models for the development of Alzheimer disease therapeutics

    ✓ Peer-reviewed Risk genes beyond APOE Nature reviews. Drug discovery

    Key finding: Early models simply damaged the rodent brain through toxins or lesions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-04-07

    Impact of occupational complexity on cognitive decline in the oldest-old

    ✓ Peer-reviewed Risk factors Aging & mental health

    Key finding: Neither work complexity (p = 0.995) nor work duration (p = 0.701) showed a significant effect on the likelihood of presenting a lower cognitive profile or developing dementia (p = 0.385 and p = 0.096, for work complexity and work duration, respectively). +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-04-07

    Cognition-Oriented Treatments for Older Adults: a Systematic Overview of Systematic Reviews

    ✓ Peer-reviewed Prevention trials Neuropsychology review

    Key finding: Meta-regression revealed that higher AMSTAR score was associated with larger effect estimates for cognitive outcomes.

    Full summary, score breakdown and related studies → Original source

  25. 2020-04-07

    Diagnostic accuracy of cerebrospinal fluid biomarkers measured by chemiluminescent enzyme immunoassay for Alzheimer disease diagnosis

    ✓ Peer-reviewed Tau biomarkers Scandinavian journal of clinical and laboratory investigation

    Key finding: The evaluation of the triad consisting of 42 aminoacid-long amyloid-beta peptide (Aβ42), total Tau (tTau) and Tau phosphorylated at threonine 181 (pTau) have been recently integrated into the research diagnostic criteria of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →