Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 12,301–12,325 of 27,380 studies, newest first · page 493 of 1096.
November 2019 25
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2019-11-18
Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results
69/100 ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: MCI prevalence varied among Hispanic/Latino backgrounds, but not as widely as reported in the previous studies. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-15
Palliative Care for Dementia: 2020 Update
55/100 ✓ Peer-reviewed End-of-life care Clinics in geriatric medicine
Key finding: Dementia management is complicated by neuropsychiatric symptoms such that the longitudinal care of a psychiatrist or other mental health provider is often an essential part of patient care and a major source of family support. +3 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-15
Neurological Changes and Depression: 2020 Update
39/100 ✓ Peer-reviewed Risk factors Clinics in geriatric medicine
Key finding: Research is then provided on neuropsychological changes associated with depression, discussing subjective cognitive impairment, mild cognitive impairment, and dementia profiles.
Full summary, score breakdown and related studies → Original source
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2019-11-15
Cognitive Reserve from the Perspective of Preclinical Alzheimer Disease: 2020 Update
55/100 ✓ Peer-reviewed Risk factors Clinics in geriatric medicine
Key finding: Current evidence is consistent with the view that higher levels of CR are associated with a delay in the onset of symptoms of mild cognitive impairment and that there may be multiple pathways by which CR exerts its protective effects.
Full summary, score breakdown and related studies → Original source
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2019-11-15
Smartphone technology for fostering goal-directed ambulation and object use in people with moderate Alzheimer's disease
39/100 ✓ Peer-reviewed Cognitive tests and assessment Disability and rehabilitation. Assistive technology
Key finding: During baseline, the mean frequency of correct target responses was virtually zero. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-15
Sex and Gender Driven Modifiers of Alzheimer's: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks
52/100 ✓ Peer-reviewed Prevention and risk Frontiers in aging neuroscience
Key finding: Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's disease (AD) is female sex. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019-11-14
Improving brain age prediction models: incorporation of amyloid status in Alzheimer's disease
39/100 ✓ Peer-reviewed Risk factors Neurobiology of aging
Key finding: Brain age indicates whether an individual's brain appears "older" than age-matched healthy peers, suggesting that they may have experienced a higher cumulative exposure to brain insults or were more impacted by those pathological insults. +3 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-14
Patient and caregiver characteristics associated with caregiver burden in Parkinson's disease: a palliative care approach
78/100 ✓ Peer-reviewed End-of-life care Annals of palliative medicine
Key finding: Patient and caregiver factors contribute to caregiver burden in persons living with PD. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-14
Brain cell type-specific enhancer-promoter interactome maps and disease - risk association
43/100 ✓ Peer-reviewed Inflammation and the immune system Science (New York, N.Y.)
Key finding: To better understand common genetic variation associated with brain diseases, we defined noncoding regulatory regions for major cell types of the human brain. +3 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-14
Progress in digital dentistry: The practical use of intraoral scanners
39/100 ✓ Peer-reviewed Digital health tools Dental materials journal
Key finding: IOSs have many advantages, such as reduce patients pain and discomfort, the operator's burden and the risk on infection, real-time impression scanning and visualization, simple replication and selective scanning, reduction of cost and waste of materials and detection of dental caries and crack . +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-13
Study partner-reported decline identifies cognitive decline and dementia risk
51/100 ✓ Peer-reviewed Long-term cohort studies Annals of clinical and translational neurology
Key finding: Functional decline is associated with risk and can be efficiently assessed by participants and study partners (SPs). +3 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-12
Brain-Immune Interactions and Neuroinflammation After Traumatic Brain Injury
39/100 ✓ Peer-reviewed Inflammation and the immune system Frontiers in neuroscience
Key finding: In the past few years, however, it was recognized that TBI causes significant morbidity weeks, months, or years after the initial injury, thereby contributing substantially to the overall burden of TBI and the decrease of life expectancy in these patients.
Full summary, score breakdown and related studies → Original source
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2019-11-12
Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition
53/100 ✓ Peer-reviewed Biomarkers Neurology
Key finding: The HCTS pattern represents a definable subgroup of non-AD pathophysiology (i.e., T - [N] + ) that is associated with cognitive impairment. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019-11-11
Genome-wide association study identifies SIAH3 locus influencing the rate of ventricular enlargement in non-demented elders
43/100 ✓ Peer-reviewed Genetics Aging
Key finding: A large genome-wide association study (GWAS) has identified seven loci associated with ventricular volume. +3 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-11
Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases
41/100 ✓ Peer-reviewed Risk factors Oxidative medicine and cellular longevity
Key finding: Any perturbation in the balance in the level of antioxidants and the reactive species results in a physiological condition called "oxidative stress."
Full summary, score breakdown and related studies → Original source
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2019-11-11
Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease
57/100 ✓ Peer-reviewed Biomarkers EMBO molecular medicine
Key finding: Overall, plasma biomarkers had smaller dynamic ranges, except for CSF and plasma P-tau which were similar. +2 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-11
Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
45/100 ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding: 18 F-PI-2620 showed peak brain uptake around 5 min after injection and fast washout from nontarget regions. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-09
Reduced expression of dMyc mitigates TauV337M mediated neurotoxicity by preventing the Tau hyperphosphorylation and inducing autophagy in Drosophila
39/100 ✓ Peer-reviewed Disease mechanisms Neuroscience letters
Key finding: We have demonstrated earlier that reduced dosage of dmyc (Drosophila homolog of human cmyc proto-oncogene) restricts tauWT mediated disease pathogenesis by regulating the phosphorylation status of tau. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019-11-08
Inflammasome-mediated innate immunity in Alzheimer's disease
39/100 ✓ Peer-reviewed Inflammation and the immune system FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Key finding: Very recently, due to experimental, genetic, and epidemiologic evidence, immune mechanisms have entered the central stage and are now believed to contribute significantly to risk, onset, and disease progression of this class of disorders.
Full summary, score breakdown and related studies → Original source
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2019-11-08
Rationale and Design of the Hamburg City Health Study
65/100 ✓ Peer-reviewed Prevention and risk European journal of epidemiology
Key finding: Endpoint assessment of the overall sample will be completed through repeated follow-up examinations and surveys as well as related individual routine data from involved health and pension insurances.
Full summary, score breakdown and related studies → Original source
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2019-11-08
Effects of a Tailored Lighting Intervention on Sleep Quality, Rest-Activity, Mood, and Behavior in Older Adults With Alzheimer Disease and Related Dementias: A Randomized Clinical Trial
63/100 ✓ Peer-reviewed Treatments Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
Key finding: Study objectives We investigated the effectiveness of a lighting intervention tailored to maximally affect the circadian system as a nonpharmacological therapy for treating problems with sleep, mood, and behavior in persons with Alzheimer disease and related dementias (ADRD). +2 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-07
Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells
41/100 ✓ Peer-reviewed Risk factors PLoS ONE
Key finding: In addition to SDH, we observed that five of the SDHIs, mostly from the latest generation, inhibit the activity of RC complex III. +2 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-07
Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression
39/100 ✓ Peer-reviewed Risk factors Biological psychiatry. Cognitive neuroscience and neuroimaging
Key finding: Older adults with depression showed increased ReHo in the bilateral dorsal anterior cingulate cortex (dACC) and the right middle temporal gyrus, with no significant findings for network homogeneity. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019-11-07
Thalamic nuclei in frontotemporal dementia: Mediodorsal nucleus involvement is universal but pulvinar atrophy is unique to C9orf72
45/100 ✓ Peer-reviewed Disease mechanisms Human brain mapping
Key finding: A cohort of 402 FTD patients (age: mean(SD) 64.3(8.2) years; disease duration: 4.8(2.8) years) was compared with 104 age-matched controls (age: 62.5(10.4) years), using an automated segmentation of T1-weighted MRIs to extract volumes of 14 thalamic nuclei.
Full summary, score breakdown and related studies → Original source
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2019-11-07
Neuroimaging of Diseases Causing Dementia
37/100 ✓ Peer-reviewed Biomarkers Neurologic clinics
Key finding: Amyloid PET is positive in Alzheimer disease (AD) and some cases of diffuse Lewy body disease, but negative in the frontotemporal dementias (FTDs). +4 more findings
Full summary, score breakdown and related studies → Original source
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