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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,051–12,075 of 27,380 studies, newest first · page 483 of 1096.

January 2020 25

  1. 2020 year only

    Air Pollution Neurotoxicity in the Adult Brain: Emerging Concepts from Experimental Findings

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Epidemiological studies are associating elevated exposure to air pollution with increased risk of Alzheimer's disease and other neurodegenerative disorders.

    Full summary, score breakdown and related studies → Original source

  2. 2020 year only

    Traffic-Related Air Pollution and Incident Dementia: Direct and Indirect Pathways Through Metabolic Dysfunction

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Higher TRAP-NOx was associated with incident dementia (HR = 1.55 for the highest versus lower tertiles, 95% CI = 1.04, 2.55). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020 year only

    Long-Term Exposure to PM10 and in vivo Alzheimer's Disease Pathologies

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: In this non-demented study population, of which 62% were cognitively normal and 38% were in mild cognitive impairment state, exposure to the highest tertile of PM10mean was associated with increased risk of amyloid-β (Aβ) positivity (odds ratio 2.19, 95% confidence interval 1.13 to 4.26) even after controlling all potential confounders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020 year only

    The Risk of Dementia in Relation to Cognitive and Brain Reserve

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Higher early-life CR (hazard ratio = 0.48, 95% CI = [0.21; 1.06]) but not early-life BR associated with a lower risk of incident dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020 year only

    Physical Inactivity is Liable to the Increased Cardiovascular Risk and Impaired Cognitive Profile

    ✓ Peer-reviewed Risk factors Current Alzheimer research

    Key finding: A high rate of physical inactivity was found among those enrolled in this project. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020 year only

    Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: When risk factor p-values were FDR-adjusted, diastolic blood pressure was significantly associated with mean perfusion. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-01-01

    Hearing and Cognitive Impairments Increase the Risk of Long-term Care Admissions

    ✓ Peer-reviewed Risk factors Innovation in aging

    Key finding: In this sample, 12.7% of clients were admitted to LTC, with a mean time to admission of 49.6 months (SE = 0.20). +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020 year only

    Epigenetic Regulation of BMAL1 with Sleep Disturbances and Alzheimer's Disease

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Methylation across all the CpGs strongly correlated with each other. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020 year only

    Future Directions for Dementia Risk Reduction and Prevention Research: An International Research Network on Dementia Prevention Consensus

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: Significant gaps in geographical location, representativeness, diversity, duration, mechanisms, and research on combinations of risk factors were identified.

    Full summary, score breakdown and related studies → Original source

  10. 2020 year only

    Drug Repositioning for Alzheimer's Disease: Finding Hidden Clues in Old Drugs

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: Despite significant enthusiasm and investment from the pharmaceutical industry, clinical trials of many disease-modifying drugs for AD have been largely unsuccessful. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2020 year only

    Transdermal Drug Delivery Systems and their Potential in Alzheimer's Disease Management

    ✓ Peer-reviewed Treatments CNS & neurological disorders drug targets

    Key finding: Many researchers have shown that the transdermal systems provide higher efficiency since the first-pass hepatic metabolism effect can be avoided and a prolonged drug release rate can be achieved.

    Full summary, score breakdown and related studies → Original source

  12. 2020 year only

    Cholinesterase as a Target for Drug Development in Alzheimer's Disease

    ✓ Peer-reviewed Treatments Methods in molecular biology (Clifton, N.J.)

    Key finding: Alzheimer's disease (AD) is an enormous healthcare challenge, and 50 million people are currently suffering from it. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020 year only

    Pharmaceutical Treatment for Alzheimer's Disease and Related Dementias: Utilization and Disparities

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Among persons diagnosed with ADRD or related symptoms, 33.3% used an approved drug over the study period. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020 year only

    Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

    ✓ Peer-reviewed Drug development Current Alzheimer research

    Key finding: LMTM given alone increased hippocampal Acetylcholine (ACh) levels, glutamate release from synaptosomal preparations, synaptophysin levels in multiple brain regions and mitochondrial complex IV activity, reduced tau pathology, partially restored ChAT immunoreactivity in the basal forebrain and reversed deficits in spatial learning. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020 year only

    Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion

    ✓ Peer-reviewed Drug development Methods in molecular biology (Clifton, N.J.)

    Key finding: Our findings highlight the therapeutic potential of C9ALS using this gapmer oligonucleotide-based approach.

    Full summary, score breakdown and related studies → Original source

  16. 2020 year only

    Contributions of Cerebro-Cerebellar Default Mode Connectivity Patterns to Memory Performance in Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: Our results showed that compared to healthy older adults, aMCI patients showed lower anti-correlation between the cerebellar DMN and several cerebral DMN regions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020 year only

    Regional Amyloid Accumulation and White Matter Integrity in Cognitively Normal Individuals

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: Our results indicated that higher global Aβ-SUVR was associated with higher mean diffusivity (MD) in the entire CN group (p = 0.023), and with both higher MD (p = 0.015) and lower fractional anisotropy (FA) (p = 0.026) in APOEɛ4 carriers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020 year only

    Head-to-Head Comparison of 18F-Florbetaben and 18F-Flutemetamol in the Cortical and Striatal Regions

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: The cortical SUVR (R2 = 0.97) and striatal SUVR (R2 = 0.95) demonstrated an excellent linear correlation between FBB and FMM using a WC as reference region. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020 year only

    Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study

    ✓ Peer-reviewed Brain scans and imaging Journal of Parkinson's disease

    Key finding: We found no significant changes in substantia nigra or cortex flortaucipir uptake in Parkinson's disease patients over two years and no association with changes in cognitive symptoms. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020 year only

    Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China

    ✓ Peer-reviewed Risk genes beyond APOE Current Alzheimer research

    Key finding: A splice mutation (p.S290C) in PSEN1 and a missense mutation (p.V717I) in APP were identified. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2020 year only

    Identification of Somatic Mutations in Dementia-related Genes in Cancer Patients

    ✓ Peer-reviewed Risk genes beyond APOE Current Alzheimer research

    Key finding: From The Cancer Genome Atlas (TCGA) database, we found 1,643 somatic mutations in the APP, PSEN1, PSEN2, MAPT, SNCA and LRRK2 genes in cancer patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020 year only

    Presenilin 1 Regulates Membrane Homeostatic Pathways that are Dysregulated in Alzheimer's Disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: Given that PS1 plays a key regulatory role in all these processes, this review will describe the role of PS1 in different cellular compartments and provide an integrated view of how PS1 dysregulation (due to mutations or other causes) could result in impairment of various cellular processes and result in a "multi-hit", integrated pathological outcome that could contribute to the etiology of AD.

    Full summary, score breakdown and related studies → Original source

  23. 2020 year only

    Early-Onset Familial Alzheimer Disease Variant PSEN2 N141I Heterozygosity is Associated with Altered Microglia Phenotype

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: Microglial expression of PSEN2 N141I resulted in impaired γ-secretase activity as well as exaggerated inflammatory cytokine release, NFκB activity, and Aβ internalization. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020 year only

    Genome-Wide Association Study Identifies SLAMF1 Affecting the Rate of Memory Decline

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: We identified rs13374761-A in SLAMF1 gene associated with less memory decline (MAF = 0.071, β= 0.0103, p = 4.14×10-8). +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020 year only

    Effects of Computerized Cognitive Training and Tai Chi on Cognitive Performance in Older Adults With Traumatic Brain Injury

    ✓ Peer-reviewed Cognitive tests and assessment The Journal of head trauma rehabilitation

    Key finding: Compared with UC, CCT increased scores on the MDRS's total, attention, and memory and those on the Mini-Mental State Examination and Telephone Interview of Cognitive Status over the 6-month intervention; TC increased scores on the MDRS's total and conceptualization and those on the Mini-Mental State Examination over the 6-month intervention, while it also increased scores on the MDRS's total and initiation/preservation and those on the Telephone Interview of Cognitive Status and reduced the time to complete the Trail Making Test B over the 12-month study. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →