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39/100

✓ Peer-reviewed alzhub usefulness score 39 out of 100. Risk factors

Topic: Brain imaging, connectivity and assessment

Older adults with depression showed increased ReHo in the bilateral dorsal anterior cingulate cortex (dACC) and the right middle temporal gyrus, with no significant findings for network homogeneity. Hierarchical linear regression models showed that higher ReHo in the dACC predicted better performance on Trail-Making Test B (p < .001; R2 = .49), Digit Span Backward (p < .05; R2 = .23), and Digit Span Total (p < .05; R2 = .23). Used as a seed, the dACC cluster of higher ReHo showed lower functional connectivity with bilateral precuneus. Higher ReHo within the dACC and right middle temporal gyrus distinguish older adults with depression from control subjects. The correlations with executive function performance support increased ReHo in the dACC as a meaningful measure of the organization of the cognitive control network and a potential compensatory mechanism. Lower functional connectivity between the dACC and the precuneus in late-life depression suggests that clusters of increased ReHo may be functionally segregated.

Key findings

Older adults with depression showed increased ReHo in the bilateral dorsal anterior cingulate cortex (dACC) and the right middle temporal gyrus, with no significant findings for network homogeneity.
Hierarchical linear regression models showed that higher ReHo in the dACC predicted better performance on Trail-Making Test B (p < .001; R2 = .49), Digit Span Backward (p < .05; R2 = .23), and Digit Span Total (p < .05; R2 = .23).
Used as a seed, the dACC cluster of higher ReHo showed lower functional connectivity with bilateral precuneus.
Higher ReHo within the dACC and right middle temporal gyrus distinguish older adults with depression from control subjects.
The correlations with executive function performance support increased ReHo in the dACC as a meaningful measure of the organization of the cognitive control network and a potential compensatory mechanism.

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Study details

Evidence strengthLow

How this study scored 39/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 22 of the 56 points we could judge it on, which is 39 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Biological psychiatry. Cognitive neuroscience and neuroimaging)
Journal's citation record	— / 4	No journal record from OpenAlex — left out of this score
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2020 — within 10 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	— / 7	No citation count (not found in OpenAlex) — left out of this score
Citations per year	— / 5	No citation count or no year — left out of this score
Impact for its field and year	— / 6	No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here	— / 6	Not yet checked against this library's citation graph — left out of this score
Still being cited	— / 4	No yearly citation counts — left out of this score
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	— / 3	No institution listed in OpenAlex — left out of this score
Multi-centre collaboration	— / 3	Institutions not listed — left out of this score
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 31901436)
Free to read	— / 2	Access not recorded — left out of this score
Points	22 / 56	Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 22 of the 56 points we could judge it on is 39 out of 100.
Total	39 / 100	—

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Cite this study APA, Vancouver, BibTeX · download .bib or .ris

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APA 7th

Respino, M., Hoptman, M. J., Victoria, L. W., Alexopoulos, G. S., Solomonov, N., Stein, A. T., et al. (2020). Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. https://doi.org/10.1016/j.bpsc.2019.10.013

Vancouver

Respino M, Hoptman MJ, Victoria LW, Alexopoulos GS, Solomonov N, Stein AT, et al. Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2020. doi:10.1016/j.bpsc.2019.10.013. PMID: 31901436.

BibTeX

@article{respino2020-31901436,
  author  = {Respino, Matteo and Hoptman, Matthew J and Victoria, Lindsay W and Alexopoulos, George S and Solomonov, Nili and Stein, Aliza T and Coluccio, Maria and Morimoto, Sarah Shizuko and others},
  title   = {{Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression}},
  journal = {Biological psychiatry. Cognitive neuroscience and neuroimaging},
  year    = {2020},
  doi     = {10.1016/j.bpsc.2019.10.013},
  pmid    = {31901436},
  url     = {https://doi.org/10.1016/j.bpsc.2019.10.013}
}

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