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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,801–10,825 of 27,380 studies, newest first · page 433 of 1096.

January 2021 24

  1. 2021-01-01

    Prospective Associations between Plasma Amyloid-Beta 42/40 and Frailty in Community-Dwelling Older Adults

    ✓ Peer-reviewed Tau biomarkers The journal of prevention of Alzheimer's disease

    Key finding: Brain amyloid-beta (Aβ) plaques, a hallmark of the pathophysiology of Alzheimer's disease, have been associated with frailty. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-01-01

    Obesity and White Matter Neuroinflammation Related Edema in Alzheimer's Disease Dementia Biomarker Negative Cognitively Normal Individuals

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Obesity is related to quantitative neuroimaging abnormalities including reduced gray matter volumes and impaired white matter microstructural integrity, although the underlying mechanisms are not well understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-01-01

    Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of biological chemistry

    Key finding: Missense mutations (e.g., R47H) of TREM2 increase risk of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-01-01

    Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Alzheimer's disease (AD) risk is associated with the TREM2 R47H variant, which impairs ligand binding and consequently microglia responses to Aβ pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-01-01

    Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH

    ✓ Peer-reviewed TREM2 and immune genetics Cell reports

    Key finding: Here, we describe that, with high-fat, high-sucrose-diet feeding, mature TIM4 pos Kupffer cells (KCs) decrease in number, while monocyte-derived Tim4 neg macrophages accumulate. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-01-01

    Mild Behavioral Impairment and Subjective Cognitive Decline Predict Cognitive and Functional Decline

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: MBI and SCD together were associated with the greatest risk of decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-01-01

    International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines

    ✓ Peer-reviewed Risk factors The journal of nutrition, health & aging

    Key finding: Ageing and a sedentary lifestyle are associated with declines in muscle function and cardiorespiratory fitness, resulting in an impaired capacity to perform daily activities and maintain independent functioning. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-01-01

    Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test

    ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD

    Key finding: The dCDT is able to operationally define graphomotor output that cannot be measured using traditional paper and pencil test administration in older health controls and participants with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-01-01

    Current State of Self-Administered Brief Computerized Cognitive Assessments for Detection of Cognitive Disorders in Older Adults: A Systematic Review

    ✓ Peer-reviewed Digital health tools The journal of prevention of Alzheimer's disease

    Key finding: Similar to past reviews, we found variability across measures with regard to psychometric rigor and potential for widescale applicability in clinical settings.

    Full summary, score breakdown and related studies → Original source

  10. 2021-01-01

    Dysphagia: Evaluation and Collaborative Management

    ✓ Peer-reviewed Digital health tools American family physician

    Key finding: Many frail older adults with progressive neurologic disease have significant but unrecognized dysphagia, which significantly increases their risk of aspiration pneumonia and malnourishment.

    Full summary, score breakdown and related studies → Original source

  11. 2021-01-01

    Ethnic Differences in Dementia Risk: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: Evidence to date suggest there are ethnic differences in risk of dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2021-01-01

    Race/Ethnic Disparities in Mild Cognitive Impairment and Dementia: The Northern Manhattan Study

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: In this diverse community-based cohort, cross-sectional data revealed significant race/ethnic disparities in the prevalence of MCI and dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-01-01

    Modifiable Barriers for Recruitment and Retention of Older Adults Participants from Underrepresented Minorities in Alzheimer's Disease Research

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: This recruitment crisis is further compounded by the fact that underrepresented and marginalized populations-particularly those identifying as a racial or ethnic minority, those with low socioeconomic status, or living in rural areas-have been historically underrepresented in ongoing AD clinical trials despite overwhelming evidence that such populations are at increased risk for developing dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2021-01-01

    Alzheimer's Disease Neuropathological Comorbidities are Common in the Younger-Old

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: Alzheimer's disease neuropathological comorbidities are highly prevalent even in the younger-old. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2021-01-01

    Mild cognitive impairment: the Manchester consensus

    ✓ Peer-reviewed Disparities Age and ageing

    Key finding: Significantly increased investment would be required in training, infrastructure and provision of fluid biomarkers and neuroimaging.

    Full summary, score breakdown and related studies → Original source

  16. 2021-01-01

    The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography

    ✓ Peer-reviewed Caregiving Science translational medicine

    Key finding: Greater rate of TAU spread was associated with baseline measures of both global Aβ burden and medial temporal lobe TAU. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2021-01-01

    Diagnosis of Early Alzheimer's Disease: Clinical Practice in 2021

    ✓ Peer-reviewed Getting a diagnosis The journal of prevention of Alzheimer's disease

    Key finding: The early and accurate detection of Alzheimer's disease-associated symptoms and underlying disease pathology by clinicians is fundamental for the screening, diagnosis, and subsequent management of Alzheimer's disease patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-01-01

    Promoting Successful Cognitive Aging: A Ten-Year Update

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Importantly, there is a growing consensus among major health organizations about recommendations to mitigate cognitive decline and promote healthy cognitive aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-01-01

    The Epidemiology of Alzheimer's Disease Modifiable Risk Factors and Prevention

    ✓ Peer-reviewed Prevention and risk The journal of prevention of Alzheimer's disease

    Key finding: As life expectancy increases and demographic ageing occurs, the global prevalence of Alzheimer's disease is expected to continue to rise especially in developing countries, leading to a costly burden of disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-01-01

    APOE Genotype Disclosure and Lifestyle Advice in a Randomized Intervention Study with Finnish Participants

    ✓ Peer-reviewed Treatments The Journal of nutrition

    Key finding: The INTε4+ group did not seem markedly more responsive to the guidance than the other groups. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-01-01

    The Cost-Effectiveness of Three Prevention Strategies in Alzheimer's Disease: Results from the Multidomain Alzheimer Preventive Trial (MAPT)

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: Our study shows that ICERS of PFA combined with MI and MI alone amounted to €21,443 and €21,543 respectively per improved Z score point compared to the placebo and are below the WTP of €50,000 while the ICER of PFA alone amounted to €111,720 per improved Z score point. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-01-01

    Psychoeducational Program for the Family Member Caregivers of People with Dementia to Reduce Perceived Burden and Increase Patient's Quality of Life: A Randomized Controlled Trial

    ✓ Peer-reviewed Treatments Journal of primary care & community health

    Key finding: Psychoeducational program is effective in reducing the family caregivers' perceived burden. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-01-01

    Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: In addition, several loci associated with rare variants, including a genome-wide significant intergenic locus near IGF1R at 15q26 (P = 1.7 × 10-9) and 6 additional loci with suggestive significance (P ≤ 5 × 10-7) such as API5 at 11p12 (P = 8.8 × 10-8) and RBFOX1 at 16p13 (P = 5.4 × 10-7) were identified. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-01-01

    Palmitoylated Prolactin-releasing Peptide Reduced Aβ Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study

    ✓ Peer-reviewed Biomarkers Current Alzheimer research

    Key finding: These results suggest palm11-PrRP31 is a promising agent for the treatment of neurodegenerative disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

December 2020 1

  1. 2020-12-31

    Spatial Distribution of Neighborhood-level Housing Prices and Its Association With All-cause Mortality in Seoul, Korea (2013–2018): a Spatial Panel Data Analysis

    ✓ Peer-reviewed Risk factors Not indexed

    Key finding: We found the common trends of increasing spatial patterning of housing prices and all-cause mortality. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →