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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,101–10,125 of 27,380 studies, newest first · page 405 of 1096.

June 2021 25

  1. 2021-06-15

    Role of Neuron and Glia in Alzheimer's Disease and Associated Vascular Dysfunction

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in aging neuroscience

    Key finding: An intricate balance between neurons, astrocytes, microglia, oligodendrocytes and vascular cells sustains the normal neuronal circuits. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-06-15

    Association of late-life depression with cognitive impairment: evidence from a cross-sectional study among older adults in India

    ✓ Peer-reviewed Disparities BMC geriatrics

    Key finding: Depression is linked to an increased risk of cognitive decline and dementia; therefore, failing to diagnose and treat LLD in later life may have significant health implications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-06-15

    Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Importantly, they suggest that these associations might be explained by a decrease of amyloidosis and tau-pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2021-06-14

    Association of plasma P-tau181 with memory decline in non-demented adults

    ✓ Peer-reviewed Biomarkers Brain Communications

    Key finding: Mixed-effect models assessed rates of memory decline in relation to baseline plasma p-tau181, and whether plasma p-tau181 significantly predicted memory decline beyond widely available clinical and genetic data (age, sex, years of education, cardiovascular and metabolic conditions, and APOEε4 status). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-06-14

    Bariatric surgery and cognitive impairment

    ✓ Peer-reviewed Risk factors Obesity (Silver Spring, Md.)

    Key finding: Bariatric surgery has been shown to improve cognition in patients with severe obesity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-06-14

    Neurotoxic Soluble Amyloid Oligomers Drive Alzheimer's Pathogenesis and Represent a Clinically Validated Target for Slowing Disease Progression

    ✓ Peer-reviewed Treatments International journal of molecular sciences

    Key finding: A large body of clinical and nonclinical evidence supports the role of neurotoxic soluble beta amyloid (amyloid, Aβ) oligomers as upstream pathogenic drivers of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-06-14

    GPS driving: a digital biomarker for preclinical Alzheimer disease

    ✓ Peer-reviewed Digital health tools Alzheimer's research & therapy

    Key finding: The findings suggest that GPS driving may serve as an effective and accurate digital biomarker for identifying preclinical AD among older adults. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-06-14

    Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Despite significant progress, applications of astrocyte biomarkers in AD remain in their early days. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-06-12

    Impact of Mediterranean Diet on Chronic Non-Communicable Diseases and Longevity

    ✓ Peer-reviewed Prevention and risk Nutrients

    Key finding: Various dietary patterns have been associated with health benefits, but the largest body of evidence in the literature is attributable to the traditional dietary habits and lifestyle followed by populations from the Mediterranean region. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2021-06-12

    Role of liraglutide in Alzheimer's disease pathology

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: The effects of LRGT on animal models show significant benefits in AD pathology and cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2021-06-12

    Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies Translational psychiatry

    Key finding: The plasma p-tau level was increased at baseline for MCI and AD dementia (mean: CN, 15.4 pg/mL; MCI, 18.4 pg/mL; AD dementia, 23.7 pg/mL; P < 0.001) and increased significantly over time at preclinical (Aβ-positive CN), prodromal (Aβ-positive MCI), and dementia (Aβ-positive dementia) stage of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-06-11

    Ethical challenges in end-stage dementia: Perspectives of professionals and family care-givers

    ✓ Peer-reviewed End-of-life care Nursing ethics

    Key finding: We found dilemmas regarding palliative care to be the main theme, including definition of the disease as terminal, choosing "comfort" over "life-prolonging," clarifying patients' wishes and deciding whether or not to use artificial feeding. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-06-11

    The Unfolded Protein Response in Immune Cells as an Emerging Regulator of Neuroinflammation

    ✓ Peer-reviewed Disease mechanisms Frontiers in aging neuroscience

    Key finding: In fact, impaired microglial function is associated with the development of neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD).

    Full summary, score breakdown and related studies → Original source

  14. 2021-06-11

    Plasma biomarkers of Alzheimer's disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

    ✓ Peer-reviewed Biomarkers Nature communications

    Key finding: Plasma biomarkers of amyloid, tau, and neurodegeneration (ATN) need to be characterized in cognitively unimpaired (CU) elderly individuals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-06-11

    The role of the medial prefrontal cortex in cognition, ageing and dementia

    ✓ Peer-reviewed Disparities Brain communications

    Key finding: Although, anatomical disparities of the rodent medial prefrontal cortex compared to the primate homologue are apparent, current rodent models have effectively implicated the medial prefrontal cortex as a neural substrate of cognitive decline within ageing and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-06-11

    GFAP positivity in neurons following traumatic brain injuries

    ✓ Peer-reviewed Biomarkers International journal of legal medicine

    Key finding: The results revealed that neuronal immunopositivity for GFAP is most likely a staining artefact as negative controls also revealed neuronal GFAP staining. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-06-10

    Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis

    ✓ Peer-reviewed Disease mechanisms Autophagy

    Key finding: We found that these autophagic pathways are non-redundant and that CMA is the main one responsible for maintenance of the metastable proteome (the one at risk of aggregation). +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2021-06-10

    Lithium: A therapeutic option in Alzheimer's disease and its prodromal stages?

    ✓ Peer-reviewed Drug development Neuroscience letters

    Key finding: These procognitive effects are associated with changes of CSF biomarkers of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  19. 2021-06-10

    G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular biomedicine

    Key finding: Along with these pathological proteins, the disease shows neuroinflammation, neuronal death, impairment in the immune function of microglia and synaptic loss, which are mediated by several important signaling pathways. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-06-09

    Retinal imaging in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Journal of neurology, neurosurgery, and psychiatry

    Key finding: Both qualitative and quantitative measurements from these retinal imaging technologies (eg, thinning of peripapillary retinal nerve fibre layer, inner retinal layer, and choroidal layer, reduced capillary density, abnormal vasodilatory response) have been shown to be associated with cognitive function impairment and risk of AD.

    Full summary, score breakdown and related studies → Original source

  21. 2021-06-09

    Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment BMJ open

    Key finding: Profiles of high risk for future dementia are well understood and are likely to concern mostly those in low-income and middle-income countries and people at greater disadvantage in high-income countries.

    Full summary, score breakdown and related studies → Original source

  22. 2021-06-09

    Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

    ✓ Peer-reviewed Inflammation and the immune system Alzheimer's research & therapy

    Key finding: Our results suggest significant mechanistic overlap between AD and COVID-19, centered on neuroinflammation and microvascular injury. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-06-09

    Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis

    ✓ Peer-reviewed Health systems and care delivery HPB : the official journal of the International Hepato Pancreato Biliary Association

    Key finding: However, rates of SA-CCY are low and factors associated with these low rates require elucidation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-06-08

    Current Status of Clinical Trials on Tau Immunotherapies

    ✓ Peer-reviewed Drug development Drugs

    Key finding: In addition, extracellular tau is only a small part of total tau, compared to intracellular tau.

    Full summary, score breakdown and related studies → Original source

  25. 2021-06-08

    Activated microglia mitigate Aβ-associated tau seeding and spreading

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine

    Key finding: Whether this Aβ-enhanced tau seeding/spreading is due to loss of microglial function or a toxic gain of function in TREM2-deficient microglia is unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →