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Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review
Valverde JM, Imani V, Abdollahzadeh A, De Feo R, Prakash M, Ciszek R, Tohka J.. Journal of imaging, 2021-04-01
Topic: Risk, prevention and care in population studies
We found 129 articles that applied transfer learning to MR brain imaging tasks. The most frequent applications were dementia-related classification tasks and brain tumor segmentation. The majority of articles utilized transfer learning techniques based on convolutional neural networks (CNNs). Only a few approaches utilized clearly brain MRI-specific methodology, and considered privacy issues, unseen target domains, or unlabeled data. We proposed a new categorization to group specific, widely-used approaches such as pretraining and fine-tuning CNNs; (4) There is increasing interest in transfer learning for brain MRI. Well-known public datasets have clearly contributed to the popularity of Alzheimer's diagnostics/prognostics and tumor segmentation as applications. Likewise, the availability of pretrained CNNs has promoted their utilization. Finally, the majority of the surveyed studies did not examine in detail the interpretation of their strategies after applying transfer learning, and did not compare their approach with other transfer learning approaches.
Key findings
- We found 129 articles that applied transfer learning to MR brain imaging tasks.
- The most frequent applications were dementia-related classification tasks and brain tumor segmentation.
- The majority of articles utilized transfer learning techniques based on convolutional neural networks (CNNs).
- Only a few approaches utilized clearly brain MRI-specific methodology, and considered privacy issues, unseen target domains, or unlabeled data.
- We proposed a new categorization to group specific, widely-used approaches such as pretraining and fine-tuning CNNs; (4) There is increasing interest in transfer learning for brain MRI.
Why it matters
This systematic review examined 129 articles that applied transfer learning to brain MRI tasks, most often for dementia-related classification. It is a review of machine learning methods for diagnosis, not a treatment, cure or prevention study.
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Study details
- Evidence strengthLow
How this study scored 42/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of imaging) |
| Journal's citation record | 1 / 4 | Journal of Imaging: journal h-index 76 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2021 — within 6 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 135 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 19.3 citations a year over 7 year(s) since 2021 |
| Impact for its field and year | 2 / 6 | Cited 2.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 3 / 4 | Cited 69 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Jussi Tohka: h-index 37 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | University of Eastern Finland: institution h-index 616 (OpenAlex) |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 34460516) |
| Free to read | 2 / 2 | Free to read |
| Total | 42 / 100 | — |
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Read the original
- DOI: 10.3390/jimaging7040066
- PubMed: 34460516
- Original source →
- Free full text: Journal of Imaging →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Valverde, J. M., Imani, V., Abdollahzadeh, A., De Feo, R., Prakash, M., Ciszek, R., et al. (2021). Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review. Journal of imaging. https://doi.org/10.3390/jimaging7040066
Vancouver
Valverde JM, Imani V, Abdollahzadeh A, De Feo R, Prakash M, Ciszek R, et al. Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review. Journal of imaging. 2021. doi:10.3390/jimaging7040066. PMID: 34460516.
BibTeX
@article{valverde2021-34460516,
author = {Valverde, J. M. and Imani, V. and Abdollahzadeh, A. and De Feo, R. and Prakash, M. and Ciszek, R. and Tohka, J.},
title = {{Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review}},
journal = {Journal of imaging},
year = {2021},
doi = {10.3390/jimaging7040066},
pmid = {34460516},
url = {https://doi.org/10.3390/jimaging7040066}
}
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