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Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models
Yang L, Xuan C, Yu C, Jin X, Zheng P, Yan J.. Nursing open, 2021-05-14
Topic: Risk, prevention and care in population studies
Aims We conducted a multi-sectoral comprehensive intervention for elderly Alzheimer Disease patients and their caregivers to improve their quality of life. Design Randomized controlled trial. Methods From June to June in 2019, 150 Alzheimer Disease patients were randomly selected from a nursing home in Zhejiang province of China, they were randomly divided into the intervention group and the control group. And they were given comprehensive and routine interventions respectively for six months. We used mixed models in our analyses to see how outcomes changed over time and how they were affected by the intervention, which could also solve the problems of missing values and data correlation. Results After six months, compared with the control group, the communication ability, housework handling ability, self-care ability and life quality of the patients in the intervention group were improved, and the quality of life and caring ability of their caregivers were also significantly improved. Conclusion The multi-sectoral collaborative care model proposed in this study integrated resources from several departments, effectively improved the quality of life of patients and their caregivers, and provided a way of care services for patients with Alzheimer Disease. Impact Multi-sectoral comprehensive intervention would improve the life quality of elderly patients with Alzheimer Disease and their caregivers.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Yang, L., Xuan, C., Yu, C., Jin, X., Zheng, P., & Yan, J. (2022). Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models. Nursing open. https://doi.org/10.1002/nop2.917
Vancouver
Yang L, Xuan C, Yu C, Jin X, Zheng P, Yan J. Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models. Nursing open. 2022. doi:10.1002/nop2.917. PMID: 33988909.
BibTeX
@article{yang2022-33988909,
author = {Yang, L. and Xuan, C. and Yu, C. and Jin, X. and Zheng, P. and Yan, J.},
title = {{Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models}},
journal = {Nursing open},
year = {2022},
doi = {10.1002/nop2.917},
pmid = {33988909},
url = {https://doi.org/10.1002/nop2.917}
}
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Key findings
- Results After six months, compared with the control group, the communication ability, housework handling ability, self-care ability and life quality of the patients in the intervention group were improved, and the quality of life and caring ability of their caregivers were also significantly improved.
Why it matters
In this 6-month randomized trial of 150 Alzheimer's disease patients in a nursing home, a multi-sectoral comprehensive intervention improved patients' communication, housework handling, self-care, and quality of life, as well as caregivers' quality of life and caring ability. The intervention addresses care and quality of life rather than curing or preventing the disease.
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Study details
- Study designrandomized controlled trial
- Evidence strengthHigh
How this study scored 56/100
Published in a peer-reviewed journal, and it is a randomised controlled trial. Scored zero for sample size and effect reported because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Nursing open) |
| Journal's citation record | 0 / 4 | Nursing Open: journal h-index 73 (OpenAlex, 2026-10-29) |
| Study design | 11 / 12 | A randomised controlled trial |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2022 — within 6 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (pubmed indexes it as a clinical or observational study) |
| Randomised / blinded | 1 / 2 | Randomised (as stated in the record) |
| Times cited | 3 / 7 | Cited 17 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 2.8 citations a year over 6 year(s) since 2022 |
| Impact for its field and year | 2 / 6 | Cited 1.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 1 / 4 | Cited 9 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Jing Yan: h-index 11 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Fudan University: institution h-index 954 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 33988909) |
| Free to read | 2 / 2 | Free to read |
| Total | 56 / 100 | — |
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