Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 2,401–2,425 of 27,380 studies, newest first · page 97 of 1096.
December 2025 25
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2025-12-01
Comparing Off‐Target Meningeal and Skull Signal in Head‐to‐Head MK‐6240 and AV‐1451 Tau PET
41/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer s & Dementia
Key finding: Average age of participants was 66 (21-88) years. 25 were biologically female and 15 were amyloid positive. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
External Validation of Joint Propagation Model‐Based Tau PET CenTauR units
52/100 ✓ Peer-reviewed Brain scans and imaging Alzheimer s & Dementia
Key finding: These analyses suggest that CenTauR harmonization increases the comparability of tau‐PET data acquired with different tracers. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-12-01
(DIADEM) Digital Assessment of Auditory Perception in Dementia : Study Protocol
52/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: We will assess the utility of auditory perceptual tests, both alone and combined with blood-based biomarkers (pTau217 and NfL), for diagnosis and prognosis in individuals with cognitive symptoms. +2 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Comparison of the Montreal Cognitive Assessment and the Mini‐Mental State Examination in community‐dwelling very old Blacks/African Americans
39/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: Participants had age mean = 81.7, SD = 4.5, range=75-93; educational attainment mean = 14.6, SD = 4.0, range=7-22, 17.2% < 12; 86.2% were women. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Correlation of the Severity of Dementia with EEG Findings
34/100 ✓ Peer-reviewed Getting a diagnosis Acta Medica International
Key finding: The mean age of the cohort was 77.4 ± 6.8 years, with 62% males and nearly equal urban–rural distribution. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease
53/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: TabCAT tests showed good convergent validity with traditional pen-and-paper tests. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Multi-modal data analysis for early detection of alzheimer’s disease and related dementias
40/100 ✓ Peer-reviewed Getting a diagnosis The Journal of Prevention of Alzheimer s Disease
Key finding: Until recently, accurate early detection of clinical symptoms associated with Alzheimer's disease (AD) and related dementias (ADRD) has been difficult. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-12-01
Diagnostic Accuracy of FDG‐PET‐CT in Dementia: Assessing False Negatives in Clinical Practice
49/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: The proportion of false negatives from FDG-PET ranged from 11-55%. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Cognitive Assessment of Dementia Patients Using Large Language Models
50/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: The study included 685 patients who underwent MDS-cognitive and 3,630 patients assessed using OASIS. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Acceptable standards for clinic‐based digital cognitive assessments: Recommendations from the Global CEO Initiative on Alzheimer's Disease
45/100 ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia
Key finding: Digital cognitive assessments (DCAs) offer a promising solution by addressing longstanding barriers to routine cognitive testing and diagnosis. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and Therapy
42/100 ✓ Peer-reviewed Prevention and risk MedComm
Key finding: At the molecular level, we explore key disruptions including proteostatic failure, aberrant phase separation, oxidative stress, neuroinflammation, synaptic dysfunction, iron dyshomeostasis, and impaired cholesterol metabolism. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Vascular Considerations for Patients Receiving Amyloid Immunotherapy
29/100 ✓ Peer-reviewed Treatments Innovation in Aging
Key finding: Amyloid-related imaging abnormalities (ARIA) in the form of edema/effusions (ARIA-E) or hemorrhagic lesions (ARIA-H) are the most impactful adverse event associated with anti-amyloid immunotherapy for Alzheimer disease.
Full summary, score breakdown and related studies → Original source
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2025-12-01
Imaging‐neuropathology evaluation of Amyloid Related Imaging Abnormality sulcal effusion in a DIAN‐TU‐001 participant treated with gantenerumab
44/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Overall PiB-PET uptake increased during the first two years (before ARIA-E) and decreased during the last two years (including ARIA-E episodes) (0.03±0.05 vs. -0.04±0.04 SUVR/year, p-value=0.01, Figure 2). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Imaging‐neuropathology evaluation of Amyloid Related Imaging Abnormality sulcal effusion in a DIAN‐TU‐001 participant treated with gantenerumab
43/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Overall PiB-PET uptake increased during the first two years (before ARIA-E) and decreased during the last two years (including ARIA-E episodes) (0.03±0.05 vs. -0.04±0.04 SUVR/year, p-value=0.01, Figure 2). +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Neuropathological evaluation of the Boston Criteria v2.0 for cerebral amyloid angiopathy in Alzheimer's disease dementia
38/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: The Boston v2.0 criteria have low accuracy in patients with AD dementia.
Full summary, score breakdown and related studies → Original source
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2025-12-01
Baseline Imaging Characteristics of Participants in the Phase II/III DIAN‐TU‐001 Tau NexGen Trial for Dominantly Inherited Alzheimer’s Disease
35/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: The study includes symptomatic DIAD participants and asymptomatic mutation carriers. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Leveraging digital twins for sample size reduction, powering secondary endpoints or subgroups in a simulated TRAILBLAZER‐ALZ 2 trial
42/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Due to the reduced variability in endpoints when using digital twins as covariates in statistical analyses, the TRAILBLAZER-ALZ 2 trial could have enrolled up to 24% fewer control arm participants to draw the same conclusions about treatment efficacy as previously reported for the study's primary outcome, the integrated Alzheimer Disease Rating Scale (iADRS) at 18 months. +3 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Model of the Impact of Pharmacological and Non-pharmacological Treatment of Alzheimer’s Disease
26/100 ✓ Peer-reviewed Treatments [in]genio revista de investigación y labor creativa
Key finding: El Alzheimer es un trastorno neurodegenerativo que afecta la cognición y memoria. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Rates of Alzheimer disease biomarker positivity stratified by by sex and race in a specialty memory clinic
38/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: The MDC used a combination of CSF tests, blood tests, and amyloid PET scans to scale up AD biomarker testing over the past three years.
Full summary, score breakdown and related studies → Original source
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2025-12-01
Partial Mitochondrial Complex I Inhibitors as a Therapy for Alzheimer Disease
32/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Like CP2, C458 and C273 weakly inhibit mtCI, leading to AMPK activation, which triggers a neuroprotective stress response. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Can Telehealth Improve Access to Amyloid-Targeting Therapies for Veterans Living With Alzheimer Disease?
29/100 ✓ Peer-reviewed Treatments Federal Practitioner
Key finding: The VHA is well-positioned to use a hybrid approach-both telehealth and in-person care-to support the provision of amyloid-targeting therapies for veterans with AD. +1 more finding
Full summary, score breakdown and related studies → Original source
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2025-12-01
Parallel Paths, Uneven Progress: Health Care Provider and Patient Perspectives on Anti‐Amyloid Therapies for Early AD
29/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: As of April 3, 2025, 944 HCPs (neurologists 14%, geriatricians 5%, primary care providers 25%) and 2,269 P/Cs engaged with the contents. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Development of a novel anti‐amyloid therapeutic: an orally administrable anti‐abeta‐oligomer compound in early preventative intervention
32/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Orally dosed D-AIP possessed favourable biostability, pharmacokinetics, and brain region distribution. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Mouse models for studying anti‐amyloid antibody‐induced ARIA
35/100 ✓ Peer-reviewed Treatments Alzheimer s & Dementia
Key finding: Thus far, studies of ARIA in amyloid mouse models have focused mainly on the development of microhemorrhages (ARIA-H) following chronic immunization. +4 more findings
Full summary, score breakdown and related studies → Original source
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2025-12-01
Lecanemab bei Alzheimer-Krankheit: Frühe Therapie ist sicher
25/100 ✓ Peer-reviewed Treatments Fortschritte der Neurologie · Psychiatrie
Key finding: Wissenschaftler*innen der Washington Universität in St. +3 more findings
Full summary, score breakdown and related studies → Original source
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