alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,901–14,925 of 27,380 studies, newest first · page 597 of 1096.

July 2017 25

  1. 2017-07-18

    Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study

    ✓ Peer-reviewed Long-term cohort studies Translational psychiatry

    Key finding: Associations between 204 serum metabolites measured at baseline (1987-1989) and cognitive change were investigated in 1035 middle-aged community-dwelling African American participants in the biracial Atherosclerosis Risk in Communities (ARIC) Study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-07-17

    Amyloid beta: structure, biology and structure-based therapeutic development

    ✓ Peer-reviewed Risk genes beyond APOE Acta pharmacologica Sinica

    Key finding: Aβ accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer's disease, which is the most common form of dementia associated with plaques and tangles in the brain.

    Full summary, score breakdown and related studies → Original source

  3. 2017-07-17

    Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Nature genetics

    Key finding: In stage 1, we genotyped 34,174 samples using a whole-exome microarray. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-07-15

    Correlation between two methods of florbetapir PET quantitative analysis

    ✓ Peer-reviewed Brain scans and imaging American journal of nuclear medicine and molecular imaging

    Key finding: This study suggests that the commercial method is comparable to the published research method of SUVr analysis for florbetapir PET images, thus facilitating the potential use of standardized quantitative approaches to PET amyloid imaging.

    Full summary, score breakdown and related studies → Original source

  5. 2017-07-15

    FGF21 Attenuates High-Fat Diet-Induced Cognitive Impairment via Metabolic Regulation and Anti-inflammation of Obese Mice

    ✓ Peer-reviewed Prevention and risk Molecular neurobiology

    Key finding: Accumulating studies suggest that overnutrition-associated obesity may lead to development of type 2 diabetes mellitus and metabolic syndromes (MetS). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-07-14

    Examining the Roles of Technology in Aging and Quality of Life

    ✓ Peer-reviewed Cognitive tests and assessment The Journals of Gerontology Series B

    Key finding: Although a small-scale study (n = 60), it suggests that older adults operate in larger geographic spaces than in the areas where they reside. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-07-14

    Cortical influences drive amyotrophic lateral sclerosis

    ✓ Peer-reviewed Digital health tools Journal of neurology, neurosurgery, and psychiatry

    Key finding: Clinical neurophysiology of the brain employing transcranial magnetic stimulation has convincingly demonstrated a presymptomatic reduction or absence of short interval intracortical inhibition, accompanied by increased intracortical facilitation, indicating cortical hyperexcitability.

    Full summary, score breakdown and related studies → Original source

  8. 2017-07-14

    Better palliative care for people with a dementia: summary of interdisciplinary workshop highlighting current gaps and recommendations for future research

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: The care experienced by people with dementia and their families has the potential to be improved; palliative care frameworks may have much to offer in this endeavour. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-07-14

    A clinicopathological approach to the diagnosis of dementia

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: The most definitive classification systems for dementia are based on the underlying pathology which, in turn, is categorized largely according to the observed accumulation of abnormal protein aggregates in neurons and glia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-07-14

    Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: When aggregating protein-truncating and missense-predicted damaging variants, we found exome-wide significant association between EOAD risk and rare variants in SORL1, TREM2, and ABCA7. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2017-07-13

    Food Priorities: Sociodemographic Variation in Constrained Choices at the Grocery Store

    ✓ Peer-reviewed Risk factors Food Systems and Health

    Key finding: The results of this study confirm that some sociodemographic groups are more likely to choose priorities that reflect contextual constraints in their lives than others. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2017-07-13

    Small-molecule PET Tracers for Imaging Proteinopathies

    ✓ Peer-reviewed Brain scans and imaging Seminars in nuclear medicine

    Key finding: Other selective Aβ and tau PET imaging compounds have followed similar pathways in their developmental processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-07-12

    Acetylcholinesterase inhibitors for treating dementia symptoms - a safety evaluation

    ✓ Peer-reviewed Treatments Expert opinion on drug safety

    Key finding: The pharmacological treatment of AD using AChEIs is associated with generally mild AEs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2017-07-12

    Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications

    ✓ Peer-reviewed Disease mechanisms Oxidative medicine and cellular longevity

    Key finding: Research has shown that neuron cells are particularly vulnerable to oxidative damage due to their high polyunsaturated fatty acid content in membranes, high oxygen consumption, and weak antioxidant defense.

    Full summary, score breakdown and related studies → Original source

  15. 2017-07-12

    Aβ seeding potency peaks in the early stages of cerebral β-amyloidosis

    ✓ Peer-reviewed Biomarkers EMBO reports

    Key finding: At all stages, the specific seeding activity of the APPPS1 extract was higher compared to that of APP23 brain extract, consistent with a more important contribution of Aβ42 than Aβ40 to seed activity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2017-07-11

    Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

    ✓ Peer-reviewed Costs and economics The Lancet. Neurology

    Key finding: Biomarkers of functional impairment, neuronal loss, and protein deposition that can be assessed by neuroimaging (ie, MRI and PET) or CSF analysis are increasingly being used to diagnose Alzheimer's disease in research studies and specialist clinical settings. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2017-07-11

    Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

    ✓ Peer-reviewed Disease mechanisms Frontiers in cellular and infection microbiology

    Key finding: Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2017-07-11

    Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load

    ✓ Peer-reviewed Biomarkers Molecular psychiatry

    Key finding: Ferritin, an iron storage and regulation protein, has been associated with Alzheimer's disease (AD); however, it has not been investigated in preclinical AD, detected by neocortical amyloid-β load (NAL), before cognitive impairment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2017-07-11

    Identifying incipient dementia individuals using machine learning and amyloid imaging

    ✓ Peer-reviewed Digital health tools Neurobiology of aging

    Key finding: Although amyloid-β protein is the core pathologic feature of Alzheimer's disease, biomarkers of neuronal degeneration are the only ones believed to provide satisfactory predictions of clinical progression within short time frames. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2017-07-10

    Implementing the compassion intervention, a model for integrated care for people with advanced dementia towards the end of life in nursing homes: a naturalistic feasibility study

    ✓ Peer-reviewed End-of-life care BMJ open

    Key finding: Implementation was feasible to differing degrees across sites, dependent on context. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2017-07-10

    Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review

    ✓ Peer-reviewed Prevention trials BMC geriatrics

    Key finding: Of all studies included in this systematic review, results from the highest quality studies, which were two randomized controlled trials, demonstrated that multi-domain CCT could lead to increases in hippocampal functional connectivity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2017-07-10

    Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism

    ✓ Peer-reviewed Down syndrome and Alzheimer's Free radical biology & medicine

    Key finding: Previous studies from our groups showed that accumulation of oxidative damage is an early event in DS neurodegeneration and that oxidative modifications of selected proteins affects the integrity of the protein degradative systems, antioxidant response, neuronal integrity and energy metabolism.

    Full summary, score breakdown and related studies → Original source

  23. 2017-07-10

    Social inappropriateness in neurodegenerative disorders

    ✓ Peer-reviewed Digital health tools International psychogeriatrics

    Key finding: Through various manifestations, social inappropriateness is frequently the first clinical sign of a neurodegenerative process, especially in AD and bvFTD, years before noticeable impairment on classical neuropsychological assessment and brain atrophy on imaging.

    Full summary, score breakdown and related studies → Original source

  24. 2017-07-09

    Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity

    ✓ Peer-reviewed Drug development Oxidative medicine and cellular longevity

    Key finding: The results of epidemiological and pathophysiological studies suggest that type 2 diabetes mellitus (T2DM) may predispose to Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2017-07-08

    The anatomy of apathy: A neurocognitive framework for amotivated behaviour

    ✓ Peer-reviewed Clinical safety Neuropsychologia

    Key finding: Apathy is a debilitating syndrome associated with many neurological disorders, including several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, and focal lesion syndromes such as stroke. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →