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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,476–8,500 of 27,380 studies, newest first · page 340 of 1096.

September 2022 25

  1. 2022-09-15

    Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine

    Key finding: As microglial responses modulated by TREM2 are central to AD pathogenesis, enhancing TREM2 signaling has been explored as an AD therapeutic strategy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-09-15

    Structures of α-synuclein filaments from human brains with Lewy pathology

    ✓ Peer-reviewed Getting a diagnosis Nature

    Key finding: These findings establish the existence of distinct molecular conformers of assembled α-synuclein in neurodegenerative disease.

    Full summary, score breakdown and related studies → Original source

  3. 2022-09-14

    Exposure to a real traffic environment impairs brain cognition in aged mice

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: Traffic-related air pollution (TRAP) has been a common public health problem, which is associated with central nervous system dysfunction according to large-scale epidemiological studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2022-09-14

    Intestinal microbiome in normal ageing, frailty and cognition decline

    ✓ Peer-reviewed Prevention trials Current opinion in clinical nutrition and metabolic care

    Key finding: Frailty syndrome, sarcopenia and cognitive decline are associated with reduced faecal microbiota biodiversity, reduced abundance of bacteria able to synthetize short-chain fatty acids (SCFA), including Faecalibacterium prausnitzii , and reduced faecal butyrate levels. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-09-14

    Association of Combined Healthy Lifestyle Factors With Incident Dementia in Patients With Type 2 Diabetes

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: We aimed to investigate whether the increased risk of dementia among individuals with diabetes can be offset by a broad combination of healthy lifestyle factors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-09-13

    Alzheimer's Disease and Inflammaging

    ✓ Peer-reviewed Risk factors Brain sciences

    Key finding: The main theory of Alzheimer's disease progress is the amyloid-β cascade hypothesis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-09-13

    Lithium in drinking water and Alzheimer's dementia: Epidemiological Findings from National Data Base of Japan

    ✓ Peer-reviewed Drug development Bipolar disorders

    Key finding: The adjusted model showed a significant inverse association of lithium levels with female, but not with male, or total prevalence of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2022-09-12

    A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency

    ✓ Peer-reviewed Risk genes beyond APOE Cell reports. Medicine

    Key finding: The established causal genes in Alzheimer's disease (AD), APP, PSEN1, and PSEN2, are functionally characterized using biomarkers, capturing an in vivo profile reflecting the disease's initial preclinical phase. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2022-09-12

    Glial Cell-Mediated Neuroinflammation in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system International journal of molecular sciences

    Key finding: It is characterized by two pathological hallmarks, the extracellular deposits of amyloid beta (Aβ) and the intraneuronal deposits of Neurofibrillary tangles (NFTs). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-09-12

    Association between urate-lowering therapies and cognitive decline in community-dwelling older adults

    ✓ Peer-reviewed Treatments Scientific reports

    Key finding: Linear mixed models were performed and results were adjusted for age, sex, body mass index (BMI), diagnosis of arterial hypertension or diabetes, baseline composite cognitive score, and MAPT intervention groups. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2022-09-12

    Home-Based Electronic Cognitive Therapy in Patients With Alzheimer Disease: Feasibility Randomized Controlled Trial

    ✓ Peer-reviewed Treatments JMIR formative research

    Key finding: Feasibility analyses were computed for participants who completed 24 weeks of Constant Therapy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-09-11

    Smoothing County-Level Sampling Variances to Improve Small Area Models’ Outputs

    ✓ Peer-reviewed Risk factors Stats

    Key finding: This affects the performance of the model (i.e., the model will not produce an estimate or will produce a low-quality modeled estimate), which results in a reduced number of official statistics published by a government agency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2022-09-09

    TauLUM, an in vivo Drosophila sensor of tau multimerization, identifies neuroprotective interventions in tauopathy

    ✓ Peer-reviewed Drug development Cell reports methods

    Key finding: Overall, our studies position tauLUM as a powerful in vivo discovery platform that leverages the advantages of the Drosophila model organism to better understand tau multimerization.

    Full summary, score breakdown and related studies → Original source

  14. 2022-09-08

    Associations of plasma phosphorylated tau181 and neurofilament light chain with brain amyloid burden and cognition in objectively defined subtle cognitive decline patients

    ✓ Peer-reviewed Biomarkers CNS Neuroscience & Therapeutics

    Key finding: After adjustment, only plasma p‐tau181 and NfL were significantly elevated in Aβ+ Obj‐SCD participants compared to Aβ− NC group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-09-08

    What Do We Know about Social and Non-Social Factors Influencing the Pathway from Cognitive Health to Dementia? A Systematic Review of Reviews

    ✓ Peer-reviewed Prevention trials Brain sciences

    Key finding: This systematic review of reviews provides a comprehensive synthesis of those factors associated with cognition in the context of dementia, identifying the role of social aspects and evidencing knowledge gaps in this area of research. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2022-09-08

    Variations in Medicare Advantage Switching Rates Among African American and Hispanic Medicare Beneficiaries With Alzheimer’s Disease and Related Dementias, by Sex and Dual Eligibility

    ✓ Peer-reviewed Health systems and care delivery The Journals of Gerontology Series B

    Key finding: The study included 2,284,175 FFS Medicare beneficiaries with an ADRD diagnosis in 2017. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2022-09-07

    Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Pre-analytical immunoprecipitation resulted in a significant increase in the area under the ROC curve (AUC) from 0.73 to 0.88 (p = 0.01547) for identifying subjects with abnormal CSF Aβ42/40. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2022-09-07

    Sustained Increase in Serum Glial Fibrillary Acidic Protein after First ST-Elevation Myocardial Infarction

    ✓ Peer-reviewed Biomarkers International journal of molecular sciences

    Key finding: It remained elevated without further relevant increases after 6 months (+11.7 (0.6, 23.5) pg/mL; p = 0.015), and 12 months (+10.3 (1.5, 22.7) pg/mL; p = 0.010) compared to the baseline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2022-09-07

    A review of respirable fine particulate matter (PM 2.5 )-induced brain damage

    ✓ Peer-reviewed Risk factors Frontiers in molecular neuroscience

    Key finding: Recent studies have shown that PM 2.5 is also strongly associated with brain damage, mainly cerebrovascular damage (stroke) and neurological damage to the brain (changes in cognitive function, dementia, psychiatric disorders, etc.).

    Full summary, score breakdown and related studies → Original source

  20. 2022-09-07

    A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Science translational medicine

    Key finding: Studies in rodent models of AD have shown that mice with increased TREM2 expression have reduced amyloid pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2022-09-07

    In vivo assessment of Lewy body and beta-amyloid copathologies in idiopathic normal pressure hydrocephalus: prevalence and associations with clinical features and surgery outcome

    ✓ Peer-reviewed Biomarkers Fluids and barriers of the CNS

    Key finding: Prevalent LB- and AD-related neurodegenerative pathologies affect a significant proportion of iNPH patients and contribute to cognitive decline (both) and motor impairment (only LB pathology) but do not significantly influence the surgical outcome at 6 months. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2022-09-06

    Decision Support Tools in Adult Long-term Care Facilities: Scoping Review

    ✓ Peer-reviewed Health systems and care delivery Journal of medical Internet research

    Key finding: In total, 17 papers were included in the final review. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2022-09-06

    TREM2/β-catenin attenuates NLRP3 inflammasome-mediated macrophage pyroptosis to promote bacterial clearance of pyogenic bacteria

    ✓ Peer-reviewed TREM2 and immune genetics Cell death & disease

    Key finding: In the present study, we demonstrate that deficiency of triggering receptors expressed on myeloid cells 2 (TREM2) significantly enhanced macrophage pyroptosis induced by four common pyogenic bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, and Escherichia coli. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2022-09-06

    Transcranial Color-Coded Doppler Cerebral Hemodynamics Following Aerobic Exercise Training: Outcomes From a Pilot Randomized Clinical Trial

    ✓ Peer-reviewed Treatments Journal for vascular ultrasound : JVU

    Key finding: This study did not demonstrate evidence of a significant change in the MFV in the middle cerebral arteries or evidence of a significant change in the PI between UPA and EPA groups. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2022-09-06

    Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers

    ✓ Peer-reviewed Genetics Acta neuropathologica

    Key finding: Clustering methods exploring the influence of all known AD risk loci on the CSF protein levels, revealed 4 biological categories suggesting multiple Aβ42 and pTau related biological pathways involved in the etiology of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →