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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,101–8,125 of 27,380 studies, newest first · page 325 of 1096.

January 2023 25

  1. 2023 year only

    An Alternative View of Familial Alzheimer's Disease Genetics

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: Similar arguments support that the pathological effects of familial Alzheimer's disease mutations in the genes PSEN1 and PSEN2 are not exerted directly via changes in AβPP cleavage to produce different ratios of Aβ length. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023 year only

    Pathological Roles of INPP5D in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Advances in experimental medicine and biology

    Key finding: The discovery of the genetic association between triggering receptor expressed on myeloid cells 2 (TREM2) with increased AD risk points to a causal link between microglia and AD pathogenesis, and revealed a crucial role of TREM2-dependent clustering of microglia around amyloid plaques that prevents Aβ toxicity to facilitate tau deposition near the plaques. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2023-01 month only

    Mendelian randomization study on the causal effect of chickenpox on dementia

    ✓ Peer-reviewed Genetics Journal of medical virology

    Key finding: Some viruses, such as varicella zoster virus, are associated with severe dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023 year only

    Identifying Genes Associated with Alzheimer's Disease Using Gene-Based Polygenic Risk Score

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: Gene-based PRS identified 389 genes with 164 of them not previously reported as AD-associated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2023 year only

    Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer's Disease-Related Biomarkers

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: Thirteen pathway clusters were identified, and eight pathway-specific PRSs were significantly associated with AD diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023 year only

    Memory for Semantically Related Objects Differentiates Cognitively Unimpaired Autosomal Dominant Mutation Carriers from Non-Carrier Family Members

    ✓ Peer-reviewed Cognitive tests and assessment The journal of prevention of Alzheimer's disease

    Key finding: Cognitively unimpaired ADAD carriers had significantly worse MESERO total scores than non-carrier family members, driven by worse performance in semantically-related object sets; group performances did not differ on semantically unrelated object sets. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2023 year only

    Liver-Specific Polygenic Risk Score Is Associated with Alzheimer's Disease Diagnosis

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The AD PRS model that was most predictive of AD diagnosis (even without APOE) was the liver AD PRS: n = 1,115; odds ratio = 2.15 (1.67-2.78), p = 3.62×10-9. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023 year only

    Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Plasma Aβ42/Aβ40 demonstrated the highest association for Aβ accumulation in the brain with an AUC 0.76 (95%CI = 0.69, 0.82) at C2 N and 0.80 (95%CI = 0.75, 0.86) at Shimadzu. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023 year only

    Early Diagnosis of Alzheimer's Disease with Blood Test; Tempting but Challenging

    ✓ Peer-reviewed Biomarkers International journal of molecular and cellular medicine

    Key finding: Studies have shown that in the preclinical stage of AD, changes in some biomarkers are measurable prior to any neurological damage or other symptoms.

    Full summary, score breakdown and related studies → Original source

  10. 2023 year only

    Reconceptualization of the Erlangen Score for the Assessment of Dementia Risk: The ERlangen Score

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The distribution of subjects between ES and ERS among the groups differed considerably, as grouping allocated 32 subjects to ES group 2, but only 2 to ERS group 2. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023 year only

    Blood Biomarkers Discriminate Cerebral Amyloid Status and Cognitive Diagnosis when Collected with ACD-A Anticoagulant

    ✓ Peer-reviewed Biomarkers Current Alzheimer research

    Key finding: Plasma AB42/40 had the highest AUC (0.833, 95% C.I. 0.767-0.899) at a cut-point of 0.0706 for discriminating between the two cerebral amyloid groups (sensitivity 76%, specificity 78.5%). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023 year only

    A 19-Year-Old Adolescent with Probable Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: In this report, we present the case of a 19-year-old male with gradual memory decline for 2 years and World Health Organization-University of California Los Angeles Auditory Verbal Learning Test (WHO-UCLA AVLT) results also showing memory impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2023 year only

    Atypical White Matter Hyperintensities Markedly Impact Plasma Neurofilament Light Chain Variability in GRN Patients

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: GRN mutations, causing frontotemporal dementia, can be associated with atypical white matter hyperintensities (WMH). +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2023-01-01

    Development of digital voice biomarkers and associations with cognition, cerebrospinal biomarkers, and neural representation in early Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: These preliminary findings suggest that derived digital biomarkers may identify cognitive impairment in preclinical and prodromal AD, and may predict disease progression. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-01-01

    Initial Experiences with Amyloid-Related Imaging Abnormalities in Patients Receiving Aducanumab Following Accelerated Approval

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: ARIA-E occurred in 6 out of 24 participants treated; all APOE-ε4 carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2023-01-01

    ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (New York, N. Y.)

    Key finding: Lecanemab can be administered without titration with modest incidence of ARIA.

    Full summary, score breakdown and related studies → Original source

  17. 2023-01-01

    Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans

    ✓ Peer-reviewed Treatments mAbs

    Key finding: Immunohistochemistry indicated increased trontinemab uptake into the brain endothelial cell layer and parenchyma, and more homogeneous distribution, compared with gantenerumab.

    Full summary, score breakdown and related studies → Original source

  18. 2023-01-01

    ACU193, a Monoclonal Antibody that Selectively Binds Soluble Aß Oligomers: Development Rationale, Phase 1 Trial Design, and Clinical Development Plan

    ✓ Peer-reviewed Cognitive tests and assessment The journal of prevention of Alzheimer's disease

    Key finding: Nonclinical data indicate that ACU193 can reduce the toxic effects of amyloid β oligomers. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-01-01

    Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer's Disease: An Overview of Tests for Clinical Practice in the United States and Europe

    ✓ Peer-reviewed Biomarkers The journal of prevention of Alzheimer's disease

    Key finding: Among cerebrospinal fluid biomarkers, all showed accurate prediction of Alzheimer's disease pathology, either based on autopsy or PET findings; greater accuracy was evident for concentration ratios (Aβ42/40 or P-tau181/Aβ42) versus individual biomarker concentrations. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2023-01-01

    Multimodal Precision Prevention - A New Direction in Alzheimer's Disease

    ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease

    Key finding: Given the heterogeneous nature of AD and the complex multi-level pathological processes leading to dementia (involving, e.g., shared risk factors, interaction of different pathology mechanisms, and their putative synergistic effects on cognition), targeting a single pathology may not be sufficient to halt or significantly impact disease progression.

    Full summary, score breakdown and related studies → Original source

  21. 2023-01-01

    Effectiveness of online-based cognitive intervention in community-dwelling older adults with cognitive dysfunction: A systematic review and meta-analysis

    ✓ Peer-reviewed Prevention trials International journal of geriatric psychiatry

    Key finding: ICT-based cognitive intervention had a positive effect on cognitive function, depression, and quality of life in older adults with MCI or mild dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-01-01

    Multi-Domain Interventions for Dementia Prevention - A Systematic Review

    ✓ Peer-reviewed Prevention trials The journal of nutrition, health & aging

    Key finding: The included studies (n=15) assessed change in cognition in response to a multidomain lifestyle intervention. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-01-01

    Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: Our results support the positive cognitive effects of boswellic acids by reducing the systemic inflammation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2023-01-01

    Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: This study has established a panel of highly important DEGs to signify the potential therapeutic targets for neuroregenerative strategy against pathogenic events associated with cerebral stroke. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2023 no date recorded — placed by publication year

    Volume of the posterior and not anterior hippocampus predicts spatial memory performance in Alzheimer´s Disease

    ✓ Peer-reviewed Risk factors Alzheimer's & Dementia

    Key finding: These results support a functional hippocampal anterior‐posterior differentiation in memory processes and further stress the importance of integrating the dissociation of the hippocampus along its long‐axis concerning functional connectivity in memory processes and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →