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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,026–12,050 of 27,380 studies, newest first · page 482 of 1096.

January 2020 25

  1. 2020-01-04

    Microstructural disruption of the right inferior fronto-occipital and inferior longitudinal fasciculus contributes to WMH-related cognitive impairment

    ✓ Peer-reviewed Digital health tools CNS neuroscience & therapeutics

    Key finding: Changes in the properties of DTI may be the potential mechanism of WMH-related MCI, especially the right IFOF and the right ILF, which may become imaging markers for predicting WMH-related cognitive dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2020-01-03

    The path forward in Alzheimer's disease therapeutics: Reevaluating the amyloid cascade hypothesis

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: An antiamyloid antibody aducanumab recently showed modest but significant efficacy in a phase 3 trial, providing important validation of amyloid as a therapeutic target. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-01-03

    Parkinson's disease: proteinopathy or lipidopathy?

    ✓ Peer-reviewed Genetics NPJ Parkinson's disease

    Key finding: Lipids play a more significant role in Parkinson's disease and its related brain disorders than is currently recognized, supporting a "lipid cascade". +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2020-01-03

    Association of Prenatal Maternal Psychological Distress With Fetal Brain Growth, Metabolism, and Cortical Maturation

    ✓ Peer-reviewed Hippocampus size on brain scans JAMA network open

    Key finding: This study found that the prevalence of maternal psychological distress in healthy, well-educated, and employed pregnant women was high, underappreciated, and associated with impaired fetal brain biochemistry and hippocampal growth as well as accelerated cortical folding. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-01-03

    Alzheimer's Disease and Diabetes: Insulin Signaling as the Bridge Linking Two Pathologies

    ✓ Peer-reviewed Disease mechanisms Molecular neurobiology

    Key finding: Studies show that chronic type II diabetes mellitus (DM) is closely associated with neurodegeneration, especially AD.

    Full summary, score breakdown and related studies → Original source

  6. 2020-01-02

    Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity

    ✓ Peer-reviewed Genetics Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Key finding: Despite this breakthrough, the effect of AD-PRS on brain function in young individuals remains unknown. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-01-02

    TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: TREM2 senses lipids and mediates myelin phagocytosis, but its role in microglial lipid metabolism is unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-01-02

    Real-space navigation testing differentiates between amyloid-positive and -negative aMCI

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Navigation testing in real space is a promising approach to identify patients with aMCI with underlying Alzheimer pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2020-01-02

    Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: We conclude that an inverse correlation between levels of inflammation in cortical areas and plasma NfL levels indicates that microglial activation may initially be protective to axons in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-01-01

    Dysfunction of the Microbiota-Gut-Brain Axis in Neurodegenerative Disease: The Promise of Therapeutic Modulation With Prebiotics, Medicinal Herbs, Probiotics, and Synbiotics

    ✓ Peer-reviewed Disease mechanisms Journal of Evidence-Based Integrative Medicine

    Key finding: While greater insights and characterization of the microbiota-gut-brain axis have been revealed over the past decade, salient questions related to the pathology, pathogenesis and clinical treatment of the axis in the context of both health and neurodegenerative disease remain and are discussed in this review.

    Full summary, score breakdown and related studies → Original source

  11. 2020 year only

    Dependence Clusters in Alzheimer Disease and Medicare Expenditures: A Longitudinal Analysis From the Predictors Study

    ✓ Peer-reviewed Costs and economics Alzheimer disease and associated disorders

    Key finding: KmL identified 2 distinct Dependence Scale clusters: (A) high initial dependence, faster decline, and (B) low initial dependence, slower decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-01-01

    Cost-Effective Care Coordination for People With Dementia at Home

    ✓ Peer-reviewed Costs and economics Innovation in aging

    Key finding: The average cost per enrollee per month was $110, or $1,320 per annum. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020 year only

    Ethnoracial Differences in Lewy Body Diseases with Cognitive Impairment

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: Presentation age was similar between groups (median 74-75 years). +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020 year only

    Alzheimer's Disease and Alzheimer's Disease-Related Dementias in Older African American and White Veterans

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: Patients had a mean age of 70.4 (±6.6) years and 97.8% were men. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020 year only

    BESI: Behavioral and Environmental Sensing and Intervention for Dementia Caregiver Empowerment-Phases 1 and 2

    ✓ Peer-reviewed Caregiving American journal of Alzheimer's disease and other dementias

    Key finding: Phases 1 and 2 results facilitated targeted changes in BESI, thus improving its overall usability for the final phase of the study, when real-time notifications and interventions will be implemented. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2020 year only

    Altered Proteostasis in Neurodegenerative Tauopathies

    ✓ Peer-reviewed Disease mechanisms Advances in experimental medicine and biology

    Key finding: Tauopathies are a heterogeneous group of neurodegenerative dementias involving perturbations in the levels, phosphorylation or mutations of the neuronal microtubule-binding protein Tau. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020 year only

    The Ubiquitin System in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Advances in experimental medicine and biology

    Key finding: Alzheimer's disease (AD) is the most common form of dementia, most prevalent in the elderly population and has a significant impact on individuals and their family as well as the health care system and the economy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2020 year only

    Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Mus treatment attenuated memory dysfunction, reduced Aβ level, and enhanced synaptic plasticity in APP/PS1 mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020 year only

    Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy

    ✓ Peer-reviewed Brain tissue and pathology Alzheimer disease and associated disorders

    Key finding: The first group (N=121, 44%) had higher level of literacy at baseline, slower decline and less variabilities over time. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020 year only

    Alzheimer's Disease: The Link Between Amyloid-β and Neurovascular Dysfunction

    ✓ Peer-reviewed Vascular contributions Journal of Alzheimer's disease : JAD

    Key finding: While prevailing evidence supports that the amyloid cascade hypothesis is a key component of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular system is also a major contributor to disease progression.

    Full summary, score breakdown and related studies → Original source

  21. 2020 year only

    Investigation of Potential Brain Microbiome in Alzheimer's Disease: Implications of Study Bias

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: In both cohorts, few differences between the control and AD groups were observed in terms of alpha and beta diversities, phyla and genera proportions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020 year only

    Healthy Gut, Healthy Brain: The Gut Microbiome in Neurodegenerative Disorders

    ✓ Peer-reviewed Disease mechanisms Current topics in medicinal chemistry

    Key finding: In the first part, we introduce the GBA and its relevance, followed by the changes occurring in the GBA during neurodegenerative disorders and then further discuss its role in the pathogenesis of these diseases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020 year only

    NLRP3 Inflammasome: A Potential Therapeutic Target in Fine Particulate Matter-Induced Neuroinflammation in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: Recent evidence has demonstrated that PM2.5 can activate NLRP3 inflammasome-mediated neuroinflammation.

    Full summary, score breakdown and related studies → Original source

  24. 2020 year only

    Risk Reduction and Prevention of Alzheimer's Disease: Biological Mechanisms of Diet

    ✓ Peer-reviewed Prevention and risk Current Alzheimer research

    Key finding: Recent evidence suggests AD associated pathologies, such as oxidative stress and inflammation, can be modulated by the lipids, vitamins, and polyphenols obtained through nutritional intake. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020 year only

    Ozone and Particulate Matter Exposure and Alzheimer's Disease: A Review of Human and Animal Studies

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Nonetheless, not all the elderly, even older female APOEɛ4 carriers, develop LOAD, suggesting that other factors, including environmental exposure, must play a role.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →