Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 26,326–26,350 of 27,380 studies, newest first · page 1054 of 1096.
September 1996 3
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1996-09-01
Prevalence of dementia in older Japanese-American men in Hawaii: The Honolulu-Asia Aging Study
57/100 ✓ Peer-reviewed How common it is JAMA
Key finding: Prevalence of Alzheimer disease in older Japanese-American men in Hawaii appears to be higher than in Japan but similar to European-ancestry populations. +1 more finding
Full summary, score breakdown and related studies → Original source
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1996-09-01
The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies
56/100 ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine
Key finding: In patients with dementia, a positive immunoassay for the 14-3-3 brain protein in cerebrospinal fluid strongly supports a diagnosis of Creutzfeldt-Jakob disease.
Full summary, score breakdown and related studies → Original source
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1996-09-01
Glial fibrillary acidic protein in the cerebrospinal fluid of patients with dementia
41/100 ✓ Peer-reviewed Biomarkers Dementia (Basel, Switzerland)
Key finding: A significant correlation between GFAP and age was found both in the total dementia group and in the controls. +1 more finding
Full summary, score breakdown and related studies → Original source
August 1996 12
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1996-08-01
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43)
40/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of neurology
Key finding: The total amount of Abeta40 and Abeta42(43) deposited was more than twice the amount deposited in cases of sporadic AD of similar disease duration, although the ratio between the extent of Abeta40 and Abeta42(43) deposition was unaltered, compared with sporadic AD.
Full summary, score breakdown and related studies → Original source
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1996-08-01
Can the controversy of the role of aluminum in Alzheimer's disease be resolved? What are the suggested approaches to this controversy and methodological issues to be considered?
36/100 ✓ Peer-reviewed Risk factors Journal of toxicology and environmental health
Key finding: Hyper-aluminemia often develops in patients with renal failure being treated with intermittent hemodialysis on a chronic basis, and in severe cases results in an encephalopathy. +4 more findings
Full summary, score breakdown and related studies → Original source
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1996-08-01
Predictors of mortality in patients diagnosed with probable Alzheimer's disease
64/100 ✓ Peer-reviewed Risk factors Neurology
Key finding: Short-term mortality is increased in patients newly diagnosed with probable AD. +4 more findings
Full summary, score breakdown and related studies → Original source
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1996-08-01
Circadian rest-activity rhythm disturbances in Alzheimer's disease
43/100 ✓ Peer-reviewed Risk factors Biological psychiatry
Key finding: First stability of the rest-activity rhythm is associated with high levels of daytime activity and high levels of environmental light resulting from seasonal effects as well as from indoor illumination. +2 more findings
Full summary, score breakdown and related studies → Original source
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1996-08-01
Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor
36/100 ✓ Peer-reviewed Drug development Brain research. Molecular brain research
Key finding: A significant fraction of the beta-amyloid precursor protein is proteolytically processed to yield large secreted forms (sAPP). +1 more finding
Full summary, score breakdown and related studies → Original source
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1996-08-01
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
71/100 ✓ Peer-reviewed Genetics Lancet (London, England)
Key finding: Overall, 156 (12.5%) women reported taking oestrogen after onset of menopause. +1 more finding
Full summary, score breakdown and related studies → Original source
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1996-08-01
Encephalopathy associated with Hashimoto thyroiditis: diagnosis and treatment
41/100 ✓ Peer-reviewed Vascular contributions Journal of neurology
Key finding: Six patients with Hashimoto thyroiditis (HT) and associated encephalopathy (HE) are described and compared with 14 well-documented cases retrieved from the literature.
Full summary, score breakdown and related studies → Original source
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1996-08-01
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies
52/100 ✓ Peer-reviewed Risk factors Neurology
Alzheimer's disease (AD) lesions are characterized by the presence of numerous inflammatory proteins.
Full summary, score breakdown and related studies → Original source
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1996-08-01
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1996-08-01
Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study
55/100 ✓ Peer-reviewed Vascular contributions Stroke
White matter findings were significantly associated with age, silent stroke, hypertension, FEV1, and income.
Full summary, score breakdown and related studies → Original source
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1996-08-01
Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
59/100 ✓ Peer-reviewed Risk genes beyond APOE Nature Medicine
Key finding: A beta 1-42(43) was elevated in plasma from subjects with FAD-linked PS1 (P < 0.0001), PS2N1411 (P = 0.009), APPK670N,M671L (P < 0.0001), and APPV7171 (one subject) mutations. +2 more findings
Full summary, score breakdown and related studies → Original source
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1996-08-01
Primary progressive apraxia in Pick's disease: a clinicopathologic study
43/100 ✓ Peer-reviewed Digital health tools Neurology
Key finding: A 62-year-old right-handed man gradually experienced increasing difficulty with speech and manual dexterity. +4 more findings
Full summary, score breakdown and related studies → Original source
July 1996 10
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1996-07-01
Follow-up study of risk factors in progressive supranuclear palsy
47/100 ✓ Peer-reviewed Risk factors Neurology
Key finding: The one previous controlled epidemiologic survey, performed at our center in 1986, found small-town experience and greater educational attainment as PSP risks, but, in retrospect, these results may have been produced by ascertainment bias. +3 more findings
Full summary, score breakdown and related studies → Original source
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1996-07-01
Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles
40/100 ✓ Peer-reviewed Drug development Acta neuropathologica
Key finding: These results indicate that in the two diseases tau undergoes the same modifications; they confirm that neurofibrillary tangles and neuropil threads like those in AD can exist independently of beta-amyloid deposits and that their presence is associated with dementia.
Full summary, score breakdown and related studies → Original source
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1996-07-01
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
36/100 ✓ Peer-reviewed Risk genes beyond APOE Neuron
Key finding: We conclude that PS1 is subject to endoproteolytic processing in vivo.
Full summary, score breakdown and related studies → Original source
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1996-07-01
Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop
57/100 ✓ Peer-reviewed Getting a diagnosis Neurology
To improve the specificity and sensitivity of the clinical diagnosis of progressive supranuclear palsy (PSP, Steele-Richardson-Olszewski syndrome), the National Institute of Neurological Disorders and Stroke (NINDS) and the Society for PSP, Inc. (SPSP) sponsored an international workshop to develop an accurate and universally accepted set of criteria for this disorder.
Full summary, score breakdown and related studies → Original source
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1996-07-01
Huntington's disease and eyeblink classical conditioning: normal learning but abnormal timing
32/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of the International Neuropsychological Society : JINS
Key finding: Performance of seven patients with HD was compared to age-matched normals, with two control subjects matched to each HD patient. +2 more findings
Full summary, score breakdown and related studies → Original source
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1996-07-01
Fronto-temporal dementia: nosology, neuropsychology, and neuropathology
40/100 ✓ Peer-reviewed Disparities Brain and cognition
Key finding: It is associated with three types of underlying histology: microvacuolation or spongiosus (frontal lobe degeneration type), gliosis with or without inclusion bodies and swollen neurones (Pick-type), and motor neurone disease type.
Full summary, score breakdown and related studies → Original source
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1996-07-01
Disability in geriatric depression
42/100 ✓ Peer-reviewed Caregiving The American journal of psychiatry
Key finding: Impairment in instrumental activities of daily living appears to be a relatively independent dimension of health status that is related to depressive symptoms, particularly anxiety and depressive ideation as well as retardation and weight loss. +4 more findings
Full summary, score breakdown and related studies → Original source
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1996-07-01
Atrophy of the corpus callosum in Alzheimer's disease versus healthy aging
45/100 ✓ Peer-reviewed Brain scans and imaging Journal of the American Geriatrics Society
Key finding: Atrophy of the CC differentiates HE and ID from AD subjects and tracks the cognitive decline of this disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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1996-07-01
Quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease
34/100 ✓ Peer-reviewed Brain scans and imaging Dementia (Basel, Switzerland)
Key finding: Autopsy material from 9 individuals with Alzheimer disease (AD) were compared to 10 age-matched, postmortem-matched controls without dementia, using standard electron microscopy. +4 more findings
Full summary, score breakdown and related studies → Original source
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1996-07-01
Survival of Medicare patients after enrollment in hospice programs
51/100 ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine
Key finding: Most patients who enter hospice care do so late in the course of their terminal illnesses.
Full summary, score breakdown and related studies → Original source
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