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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,826–26,850 of 27,380 studies, newest first · page 1074 of 1096.

December 1992 1

  1. 1992-12-01

    Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type

    ✓ Peer-reviewed Getting a diagnosis Archives of neurology

    Key finding: Category fluency demonstrated the greatest degree of discrimination between patients with DAT and normal control subjects (sensitivity, 100%; specificity, 92.5%); letter fluency was the least accurate (sensitivity, 89%; specificity, 85%). +2 more findings

    Full summary, score breakdown and related studies → Original source

November 1992 8

  1. 1992-11-01

    Complement activation by beta-amyloid in Alzheimer disease

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences

    Key finding: Although several lines of evidence suggest that beta-AP is neurotoxic, a mechanism for beta-AP toxicity in AD brain remains unclear.

    Full summary, score breakdown and related studies → Original source

  2. 1992-11-01

    Disease-specific patterns of locus coeruleus cell loss

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of neurology

    Key finding: There was comparable cell loss in all three diseases (approximately 60%) compared with aged normal subjects, and there was a significant loss of nucleus subcoeruleus cells specifically in patients with Parkinson's disease (63%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1992-11-01

    Clinical and neuropathological correlates of depression in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Psychological medicine

    Key finding: Recent evidence suggests that a noradrenergic deficit originating from neuronal degeneration in brainstem nuclei may represent an organic correlate of these disturbances. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1992-11-01

    A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group

    ✓ Peer-reviewed Clinical trials JAMA

    Key finding: These results confirm the efficacy and safety of tacrine in some patients with Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1992-11-01

    Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The peptide comprising the carboxyl-terminal 100 amino acids of the beta-amyloid precursor protein (beta APP) has been shown to aggregate into amyloid-like fibrils in vitro and to be neurotoxic, suggesting that this fragment may play a role in the etiology of Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1992-11-01

    Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region

    ✓ Peer-reviewed Risk genes beyond APOE American journal of human genetics

    Key finding: Previous studies have identified three mutations at APP codon 717 which are pathogenic for Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1992-11-01

    Leukoaraiosis and dementia in hypertensive patients

    ✓ Peer-reviewed Digital health tools Stroke

    Key finding: Hypertension-caused arteriosclerotic changes of the long penetrating medullary arteries may cause misery perfusion and later ischemic damage in the periventricular white matter. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1992-11-01

    Instrumental activities of daily living as a screening tool for cognitive impairment and dementia in elderly community dwellers

    ✓ Peer-reviewed Getting a diagnosis Journal of the American Geriatrics Society

    Key finding: The four IADL score could be incorporated into the screening procedure for dementia in elderly community dwellers.

    Full summary, score breakdown and related studies → Original source

October 1992 8

  1. 1992-10-01

    A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group

    ✓ Peer-reviewed Treatments The New England journal of medicine

    Key finding: In this short-term study in patients with Alzheimer's disease who were selected for apparent responsiveness to tacrine, treatment with tacrine resulted in a statistically significant reduction in the decline of cognitive function, although this reduction was not large enough to be detected by the study physicians' global assessments of the patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1992-10-01

    Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Markers on chromosome 14 gave highly significant positive lod scores in early-onset non-Volga German kindreds; a Zmax of 9.15 (theta = 0.01) was obtained with the marker D14S43 at 14q24.3. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1992-10-01

    Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

    ✓ Peer-reviewed Tau biomarkers Brain : a journal of neurology

    Key finding: In contrast, no increases in CSF QUIN were found in chronic neurodegenerative disorders, depression or myoclonic seizure disorders, while CSF kynurenic acid concentrations were significantly lower in Huntington's disease and Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1992-10-01

    Production of the Alzheimer amyloid beta protein by normal proteolytic processing

    ✓ Peer-reviewed Tau biomarkers Science (New York, N.Y.)

    Key finding: Human mononuclear leukemic (K562) cells expressing a beta AP-bearing, carboxyl-terminal beta APP derivative released significant amounts of a soluble 4-kilodalton beta APP derivative essentially identical to the beta AP deposited in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  5. 1992-10-01

    Atrophy of medial temporal lobes on MRI in "probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates.

    ✓ Peer-reviewed Brain scans and imaging Journal of Neurology Neurosurgery & Psychiatry

    Magnetic resonance imaging (MRI) has shown a great reduction in medial temporal lobe and hippocampal volume of patients with Alzheimer's disease as compared to controls.

    Full summary, score breakdown and related studies → Original source

  6. 1992-10-01

    Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The expression of the neural-specific isoform containing 695 amino acids, beta APP695, is consistent with a role for the protein in neuronal development. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1992-10-01

    Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: To investigate whether cellular APP processing is controlled by cell-surface neurotransmitter receptors, human embryonic kidney (293) cell lines were transfected with the genes for human brain muscarinic acetylcholine receptors. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1992-10-01

    Changes in brain functional connectivity in Alzheimer-type and multi-infarct dementia

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: Areas that were linked by dense narrow bands of long corticocortical fibres showed greatly diminished coherence in subjects with DAT; among MID subjects, this coherence was not significantly affected. +3 more findings

    Full summary, score breakdown and related studies → Original source

September 1992 8

  1. 1992-09-01

    Predictors of cognitive and functional progression in patients with probable Alzheimer's disease

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: Scores on the Mini Mental State Examination and a combination of instrumental and self-maintenance scale of activities of daily living were regressed on time of examination (measured in 6-month increments) to estimate cognitive and functional progression rates in individual patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1992-09-01

    Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

    ✓ Peer-reviewed Tau biomarkers Nature

    Key finding: These findings demonstrate that A beta is produced and released both in vivo and in vitro.

    Full summary, score breakdown and related studies → Original source

  3. 1992-09-01

    Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: We present the anatomic basis of these two protocols and our results in normal control subjects.

    Full summary, score breakdown and related studies → Original source

  4. 1992-09-01

    Amyloid β-peptide is produced by cultured cells during normal metabolism

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: Unexpected identification of the 4K (M(r) 4,000) A beta and a truncated form of A beta (approximately 3K) in media from cultures of primary cells and untransfected and beta-APP-transfected cell lines grown under normal conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1992-09-01

    Spectrum of human immunodeficiency virus-associated neocortical damage

    ✓ Peer-reviewed Inflammation and the immune system Annals of neurology

    Key finding: AIDS dementia complex (ADC) is a severe form of this disease seen in 20 to 30% of terminally ill patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1992-09-01

    The mini-mental state examination: a comprehensive review

    ✓ Peer-reviewed Cognitive tests and assessment Journal of the American Geriatrics Society

    Key finding: The purpose of this paper is to provide a comprehensive review of information accumulated over the past 26 years regarding the psychometric properties and utility of the Mini-Mental State Examination (MMSE). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1992-09-01

    Acoustic analysis in the differentiation of Parkinson's disease and major depression

    ✓ Peer-reviewed Digital health tools Journal of psycholinguistic research

    Key finding: Of the acoustic variables studied, M.D. patients had significantly reduced rates of speech compared with P.D. patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 1992-09-01

    Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease

    ✓ Peer-reviewed How common it is Annals of neurology

    Key finding: A higher prevalence of dementia in individuals with fewer years of education has suggested that education may protect against Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →