Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 25,026–25,050 of 27,380 studies, newest first · page 1002 of 1096.
November 2001 25
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2001-11-01
Prevalence of cognitive impairment: data from the Indianapolis Study of Health and Aging
67/100 ✓ Peer-reviewed Vascular contributions Neurology
Key finding: Cognitive impairment short of dementia affects nearly one in four community-dwelling elders and is a major risk factor for later development of dementia.
Full summary, score breakdown and related studies → Original source
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2001-11-01
Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study
36/100 ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry research
Key finding: No significant differences were found between schizophrenic and control subjects in mean values for prefrontal gray matter volume in either hemisphere. +4 more findings
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2001-11-01
Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus
43/100 ✓ Peer-reviewed Hippocampus size on brain scans The European journal of neuroscience
Key finding: There was no evidence of neuronal cell loss or other major morphological alterations in any of the groups, nor was there a significant change in the distribution pattern of synaptophysin or Alz-50.
Full summary, score breakdown and related studies → Original source
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2001-11-01
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury
36/100 ✓ Peer-reviewed Hippocampus size on brain scans The Journal of neuroscience : the official journal of the Society for Neuroscience
Key finding: Second, we found persistently enhanced susceptibility to pentylenetetrazole-induced convulsions 15 weeks after TBI. +1 more finding
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2001-11-01
Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation
36/100 ✓ Peer-reviewed Inflammation and the immune system Neurochemistry international
Key finding: We found frequent colocalization of hyperphosphorylated tau protein (AT8 antibody) and activated MAPK-p38 in neurons and in dystrophic neurites in Alzheimer brain, and frequent association of these structures with activated microglia overexpressing IL-1. +3 more findings
Full summary, score breakdown and related studies → Original source
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2001-11-01
Immunological aspects of microglia: relevance to Alzheimer's disease
36/100 ✓ Peer-reviewed Inflammation and the immune system Neurochemistry international
Key finding: Neuritic plaques are one of the main neuropathological findings in AD, and the major protein component is the beta-amyloid protein (A beta). +4 more findings
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2001-11-01
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2001-11-01
The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease
42/100 ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging
Key finding: Even early, nonfibrillar amyloid deposits in Alzheimer's disease contain such astrocytes, and the numbers and degree of activation of these wax and wane with the subsequent neuritic pathology of plaque evolution. +3 more findings
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2001-11-01
Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity
45/100 ✓ Peer-reviewed Inflammation and the immune system Journal of virology
Key finding: Previous studies suggest that brain-derived viruses are macrophage tropic (M-tropic) and principally use CCR5 for virus entry. +3 more findings
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2001-11-01
Interleukin-1, neuroinflammation, and Alzheimer's disease
44/100 ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging
Key finding: Il-1 is overexpressed in Alzheimer brain, and this overexpression is directly related to plaque formation and progression, nonsensical growth of dystrophic neurites, and neuronal overexpression of acetylcholinesterase. +3 more findings
Full summary, score breakdown and related studies → Original source
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2001-11-01
Inflammation, autotoxicity and Alzheimer disease
44/100 ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging
Key finding: It involves an innate immune reaction of sufficient intensity that self attack on neurons occurs. +3 more findings
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2001-11-01
Dementia and cognitive impairment three months after stroke
46/100 ✓ Peer-reviewed Cognitive tests and assessment European journal of neurology
Key finding: Three months after stroke, patients were submitted to a neuropsychological evaluation that included the Mini-Mental State Examination (MMSE), a complementary battery to assess specific cognitive domains, the Hamilton Depression Rating Scale (HDRS) and the Blessed Dementia Scale (BDS). +3 more findings
Full summary, score breakdown and related studies → Original source
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2001-11-01
Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease
45/100 ✓ Peer-reviewed Cognitive tests and assessment Neurochemistry international
Key finding: The hypothesis that the overexpression of S100B in Alzheimer brain is related to the progression of clinical symptoms was addressed in living persons by measuring S100B concentrations in cerebrospinal fluid (CSF) from AD patients with a broad range of clinical dementia severity and from healthy older persons. +3 more findings
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2001-11-01
[Diagnostic value of tau in cerebrospinal fluid in alzheimer disease]
33/100 ✓ Peer-reviewed Tau biomarkers Zhonghua yi xue za zhi
Key finding: The measurement of CSF specimens from Netherlands Brain Bank showed that the levels of total tau and p-tau in CSF specimens of AD patients were significantly higher than those in CSF of patients with VD and non-dementia neurological disorders, and of age-matched non- +3 more findings
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2001-11-01
Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain
43/100 ✓ Peer-reviewed Risk genes beyond APOE Brain research
Key finding: The initial cleavage by BACE is followed by gamma-secretase cleavage of the C-terminal APP fragment. +3 more findings
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2001-11-01
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
44/100 ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging
Key finding: The mechanism for these effects and the impact on behavior are unknown. +3 more findings
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2001-11-01
Evidence for abnormal cortical functional connectivity during working memory in schizophrenia
49/100 ✓ Peer-reviewed Lewy body dementia The American journal of psychiatry
Key finding: Pronounced disruptions of distributed cooperative activity in schizophrenia were found. +1 more finding
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2001-11-01
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease
74/100 ✓ Peer-reviewed How common it is The New England journal of medicine
Key finding: The long-term use of NSAIDs may protect against Alzheimer's disease but not against vascular dementia. +2 more findings
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2001-11-01
Reduced employment in caregivers of frail elders: impact of ethnicity, patient clinical characteristics, and caregiver characteristics
58/100 ✓ Peer-reviewed Disparities The journals of gerontology. Series A, Biological sciences and medical sciences
Key finding: Our goal was to determine the patient and caregiver characteristics associated with the reduction of employment hours in caregivers of frail elders. +3 more findings
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2001-11-01
Factors associated with long-term institutionalization of older people with dementia: data from the Canadian Study of Health and Aging
49/100 ✓ Peer-reviewed Caregiving The journals of gerontology. Series A, Biological sciences and medical sciences
Key finding: Screening caregivers for burden and depression and designing interventions to decrease the consequences of behavioral disturbance on caregivers would be relevant avenues to explore to decrease institutionalization of people with dementia. +3 more findings
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2001-11-01
National estimates of the quantity and cost of informal caregiving for the elderly with dementia
54/100 ✓ Peer-reviewed Caregiving Journal of general internal medicine
Key finding: After adjusting for sociodemographics, comorbidities, and potential caregiving network, those with normal cognition received an average of 4.6 hours per week of informal care. +3 more findings
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2001-11-01
Idiopathic normal pressure hydrocephalus: a systematic review of diagnosis and outcome
55/100 ✓ Peer-reviewed Getting a diagnosis Neurosurgery
Key finding: Shunting INPH is associated with an approximately 29% rate of significant improvement and a 6% significant complication rate. +2 more findings
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2001-11-01
Nurses' recognition of delirium and its symptoms: comparison of nurse and researcher ratings
56/100 ✓ Peer-reviewed Getting a diagnosis Archives of internal medicine
Key finding: Delirium occurred in 239 (9%) of 2721 observations or 131 (16%) of 797 patients. +4 more findings
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2001-11-01
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome
71/100 ✓ Peer-reviewed Getting a diagnosis JAMA
Key finding: Progressive dementia was detected by PET with a sensitivity of 93% (191/206) and a specificity of 76% (59/78). +3 more findings
Full summary, score breakdown and related studies → Original source
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2001-11-01
Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease
56/100 ✓ Peer-reviewed Getting a diagnosis Archives of neurology
Key finding: An international group of clinical and basic scientists participated in the Frontotemporal Dementia and Pick's Disease Criteria Conference at the National Institutes of Health in Bethesda, Md, on July 7, 2000, to reassess clinical and neuropathological criteria for the diagnosis of frontotemporal dementia (FTD). +3 more findings
Full summary, score breakdown and related studies → Original source
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