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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,901–24,925 of 27,380 studies, newest first · page 997 of 1096.

April 2002 1

  1. 2002-04-01

    Association between apolipoprotein E genotype and Alzheimer disease in African American subjects

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Compared with individuals with the APOEepsilon3/epsilon3, the odds of having AD were significantly increased among those with 1 or more copies of the epsilon4 allele; the odds ratio (OR) for the epsilon3/epsilon4 genotype was 2.6 (95% confidence interval [CI], 1.8-3.7), and the OR for the epsilon4/epsilon4 genotype was 10.5 (95% CI, 5.1-21.8). +2 more findings

March 2002 24

  1. 2002-03-18

    Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of cell biology

    Key finding: The data suggests a linkage between tau and APP trafficking, which may be significant in Alzheimer's disease.

  2. 2002-03-05

    A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping

    ✓ Peer-reviewed Cognitive tests and assessment European journal of nuclear medicine and molecular imaging

    Key finding: Forty-eight AD, 23 DLB and 20 age-matched control subjects participated. +3 more findings

  3. 2002-03-01

    Comparison of Citalopram, Perphenazine, and Placebo for the Acute Treatment of Psychosis and Behavioral Disturbances in Hospitalized, Demented Patients

    ✓ Peer-reviewed Clinical safety American Journal of Psychiatry

    Key finding: Patients treated with citalopram or perphenazine showed statistically significant improvement on several Neurobehavioral Rating Scale factor scores. +3 more findings

  4. 2002-03 month only

    Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease

    ✓ Peer-reviewed Genetics Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

    Key finding: Consistent with the altered pathology and enhanced risk for AD associated with inheritance of the epsilon4 allele, we conclude that APOE epsilon4 is a risk factor for AD not due to a pathological gain of function of apoE4 but to a loss of protective function of apoE3.

  5. 2002-03-01

    Clinical predictive factors of subthalamic stimulation in Parkinson's disease

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: The selection criteria were severe parkinsonian motor disability, clear response of symptoms to levodopa, occurrence of disabling levodopa-related motor complications and the absence of dementia and significant abnormalities on brain MRI. +1 more finding

  6. 2002-03-01

    Prevalence and impact of medical comorbidity in Alzheimer's disease

    ✓ Peer-reviewed Health systems and care delivery The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Despite the limitation of a cross-sectional design, our initial findings suggest that there is a strong association between medical comorbidity and cognitive status in AD. +2 more findings

  7. 2002-03-01

    Serum lipoprotein levels, statin use, and cognitive function in older women

    ✓ Peer-reviewed Drug development Archives of neurology

    Key finding: High LDL and total cholesterol levels are associated with cognitive impairment, and lowering these lipoprotein levels may be a strategy for preventing impairment. +4 more findings

  8. 2002-03-01

    Glycogen synthase kinase 3: an emerging therapeutic target

    ✓ Peer-reviewed Drug development Trends in molecular medicine

    Key finding: GSK-3 inhibitors might prove useful as therapeutic compounds in the treatment of conditions associated with elevated levels of enzyme activity, such as type 2 diabetes and Alzheimer's disease.

  9. 2002-03-01

    Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine

    ✓ Peer-reviewed Treatments Biochemistry

    Key finding: It revealed that the carbamyl moiety is covalently linked to the active-site serine, with the leaving group, (-)-S-3-[1-(dimethylamino)ethyl]phenol, being retained in the "anionic" site. +1 more finding

  10. 2002-03-01

    A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells

    ✓ Peer-reviewed Drug development The Journal of pharmacology and experimental therapeutics

    Key finding: We observed that GLP-1 and exendin-4 induced neurite outgrowth in a manner similar to nerve growth factor (NGF), which was reversed by coincubation with the selective GLP-1 receptor antagonist exendin (9-39). +1 more finding

  11. 2002-03-01

    Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review

    ✓ Peer-reviewed Genetics American journal of epidemiology

    Key finding: Allelic variation in apo var epsilon is consistently associated with plasma concentrations of total cholesterol, LDL cholesterol, and apo B (the major protein of LDL, VLDL, and chylomicrons). +1 more finding

  12. 2002-03-01

    End-of-life care in dementia: a review of problems, prospects, and solutions in practice

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: The purpose of this literature review was to assess the current state of affairs in end-of-life care for persons with dementia, to identify barriers to the provision of high-quality care, and to describe exemplary programs that have discovered ways to overcome these barriers. +4 more findings

  13. 2002-03-01

    The prevalence and documentation of impaired mental status in elderly emergency department patients

    ✓ Peer-reviewed Clinical safety Annals of emergency medicine

    Key finding: Study objective We sought to determine the prevalence of mental status impairment in elderly emergency department patients and to assess documentation of and referrals by emergency physicians for mental status impairment after discharge from the ED.

  14. 2002-03-01

    What is cognitive reserve? Theory and research application of the reserve concept

    ✓ Peer-reviewed Disease mechanisms Journal of the International Neuropsychological Society

    The idea of reserve against brain damage stems from the repeated observation that there does not appear to be a direct relationship between the degree of brain pathology or brain damage and the clinical manifestation of that damage.

  15. 2002-03-01

    Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice

    ✓ Peer-reviewed Inflammation and the immune system The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: This reduction was associated with a dramatic increase in the number of microglia expressing major histocompatibility complex-II antigen, a marker for microglial activation. +3 more findings

  16. 2002-03-01

    Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease

    ✓ Peer-reviewed Brain tissue and pathology Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: AD changes are frequently present in brains of demented PD patients. +3 more findings

  17. 2002-03-01

    Provisional diagnostic criteria for depression of Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    The authors, a group of investigators with extensive research and clinical experience related to both late-life depression and Alzheimer disease (AD), propose provisional affective and behavioral inclusion and exclusion diagnostic criteria for Depression of AD.

  18. 2002-03-01

    Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of neurology, neurosurgery, and psychiatry

    Key finding: The short and long term effects of CEIs were evaluated in 135 patients with probable Alzheimer's disease relative to 135 patients who were never exposed to CEIs matched by age, education, duration of the symptoms, and cognitive status. +3 more findings

  19. 2002-03-01

    Functional deficits in patients with mild cognitive impairment: prediction of AD

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: These findings indicate that in patients with MCI, the patient's lack of awareness of functional deficits identified by informants strongly predicts a future diagnosis of AD. +4 more findings

  20. 2002-03-01

    Cytonectin expression in Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of neuropathology and experimental neurology

    Key finding: The protein is overexpressed in Alzheimer disease entorhinal cortex as compared to normal age-matched controls.

  21. 2002-03-01

    Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam Scan Study

    ✓ Peer-reviewed Risk factors Annals of neurology

    Key finding: Silent brain infarcts and white matter lesions are frequently seen on magnetic resonance imaging in healthy elderly people and both are associated with an increased risk of stroke and dementia. +4 more findings

  22. 2002-03-01

    Revealing a hidden problem. An evaluation of a community dementia case-finding program from the Indian 10/66 dementia research network

    ✓ Peer-reviewed Disparities International journal of geriatric psychiatry

    Key finding: This simple cost-effective case-finding method can be of practical use in the development of community based dementia care services in India and other developing countries with similar health care systems.

  23. 2002-03-01

    Sensitivity and specificity of cognitive and functional screening instruments for dementia: the Indo-U.S. Dementia Epidemiology Study

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: The sensitivity of the HMSE alone was nonsignificantly improved by the addition of either the EASI or the neuropsychological battery, whereas its specificity was significantly decreased by either addition.

  24. 2002-03-01

    A descriptive evaluation of eligibility for therapy among veterans with chronic hepatitis C virus infection

    ✓ Peer-reviewed Disparities Journal of clinical gastroenterology

    Key finding: Goal To assess the number of chronic hepatitis C patients eligible for therapy. +1 more finding

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