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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,276–26,300 of 27,380 studies, newest first · page 1052 of 1096.

December 1996 2

  1. 1996-12-01

    A multicenter double-blind study of controlled-release physostigmine for the treatment of symptoms secondary to Alzheimer's disease. Physostigmine Study Group

    ✓ Peer-reviewed Treatments Neurology

    Key finding: This study demonstrated statistically significant differences between physostigmine and placebo on both a performance-based cognitive functioning instrument and a clinician's global evaluation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1996-12-01

    A family intervention to delay nursing home placement of patients with Alzheimer disease. A randomized controlled trial

    ✓ Peer-reviewed Treatments JAMA

    Key finding: A program of counseling and support can substantially increase the time spouse-caregivers are able to care for AD patients at home, particularly during the early to middle stages of dementia when nursing home placement is generally least appropriate.

    Full summary, score breakdown and related studies → Original source

November 1996 22

  1. 1996-11-01

    Use of tube feeding to prevent aspiration pneumonia

    ✓ Peer-reviewed Costs and economics The Lancet

    Key finding: For the neurogenic group, prevention of aspiration pneumonia is a common therapeutic goal. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1996-11-01

    Deficient glutamate tranport is associated with neurodegeneration in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Annals of Neurology

    Key finding: In AD, glutamate transporter activity as assessed by D-[3H]aspartate binding is decreased; however, it is not clear to what extent it is associated with the neurodegenerative process and cognitive alterations. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1996-11-01

    The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial. The Donepezil Study Group

    ✓ Peer-reviewed Treatments Dementia (Basel, Switzerland)

    Key finding: The improvements in ADAS-cog were statistically significantly greater with donepezil 5 mg/day than with placebo. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1996-11-01

    Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: Similarly, the Abeta1-42(43)/Abeta1-40 ratio is elevated in the brains of young transgenic animals coexpressing a chimeric amyloid precursor protein (APP) and an FAD-linked PS1 variant compared with brains of transgenic mice expressing APP alone or transgenic mice coexpressing wild-type human PS1 and APP.

    Full summary, score breakdown and related studies → Original source

  5. 1996-11-01

    Importance of diffuse aspiration bronchiolitis caused by chronic occult aspiration in the elderly

    ✓ Peer-reviewed Clinical safety Chest

    Key finding: In the present study, a total of 4,880 consecutive autopsies were reviewed and we found 31 patients with DAB (0.64%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1996-11-01

    Validation of a cognitive test for delirium in medical ICU patients

    ✓ Peer-reviewed Clinical safety Psychosomatics

    Key finding: Patients with delirium, dementia, depression, and schizophrenia were administered a newly developed test designed to identify delirium in an intensive care unit (ICU) setting. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1996-11-01

    Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Experimental neurology

    Key finding: These reductions likely follow regional synaptic loss or dysfunction and reflect physiological down-regulation of gene expression for glucose delivery, oxidative phosphorylation (OXPHOS), and energy consumption in brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1996-11-01

    Quantitative Polymerase Chain Reaction Does not Improve Preoperative Prostate Cancer Staging: A Clinicopathological Molecular Analysis of 121 Patients

    ✓ Peer-reviewed Risk factors The Journal of Urology

    Key finding: Circulating PSA producing cells were present in 29 of 33 patients (88 percent) with metastatic prostate cancer. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1996-11-01

    Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Neurobiology of aging

    Key finding: This has been a subject of much controversy, with separate studies comparing various clinical and neuropathological indices in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1996-11-01

    Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: We have proposed that one molecule common to these abnormal processes is a fragment of the Alzheimer amyloid precursor protein (APP) comprising the C-terminal 100 amino acids of this molecule (APP-C100). +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1996-11-01

    Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Whereas the 40-amino acid form of A beta (A beta 40) accounts for approximately 90% of all A beta normally released from cells, it appears to contribute only to later phases of the pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 1996-11-01

    Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF

    ✓ Peer-reviewed Lewy body dementia Journal of neurochemistry

    Key finding: The levels were increased in ALS (1,743 +/- 1,661 ng/L; mean +/- SD) and AD (346 +/- 176 ng/L) compared with controls (138 +/- 31 ng/L; p < 0.0001 for both). +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 1996-11-01

    Brain cognition and metabolism in Down syndrome adults in association with development of dementia

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroreport

    Key finding: To identify changes in brain functions associated with the development of dementia, brain metabolism and cognition were assessed repeatedly in 12 adults with Down syndrome (DS) using positron emission tomography and neuropsychological tests. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 1996-11-01

    Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Archives of neurology

    Key finding: A consistent alteration in platelet APP isoforms has been found in Alzheimer disease and Down syndrome. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 1996-11-01

    Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These findings suggest that Ts65Dn mice may be used to study certain developmental and degenerative abnormalities in the DS brain.

    Full summary, score breakdown and related studies → Original source

  16. 1996-11-01

    Association of diabetes mellitus and dementia: the Rotterdam Study

    ✓ Peer-reviewed Risk factors Diabetologia

    Key finding: Multiple logistic regression analyses, adjusting for age and sex differences, revealed a positive association between diabetes and dementia (odds ratio: 1.3, 95% confidence interval 1.0-1.9). +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 1996-11-01

    Physical restraints in geriatric care in Sweden: prevalence and patient characteristics

    ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society

    Key finding: This study has shown that physical restraints are used frequently in geriatric care in Sweden and that cognitive and physical impairments relate very closely to the use of physical restraints. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 1996-11-01

    Corticobasal degeneration with primary progressive aphasia and accentuated cortical lesion in superior temporal gyrus: case report and review

    ✓ Peer-reviewed Digital health tools Acta neuropathologica

    Key finding: A survey of 28 pathologically evaluated cases of CBD revealed two similar cases, both of which began with progressive aphasia and presented cortical degeneration in the superior temporal gyrus.

    Full summary, score breakdown and related studies → Original source

  19. 1996-11-01

    Nonfluent progressive aphasia and semantic dementia: a comparative neuropsychological study

    ✓ Peer-reviewed Digital health tools Journal of the International Neuropsychological Society : JINS

    Key finding: Performance on nonverbally mediated tests of semantic knowledge is impaired in semantic dementia only. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 1996-11-01

    Does the Clock Drawing Test predict cognitive decline in older persons independent of the Mini-Mental State Examination? The FINE Study Group. Finland, Italy, The Netherlands Elderly

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: A preplanned analysis of data collected during the second (1991) and the third (1995) follow-up of the Italian rural cohorts of the FINE Study (Finland, Italy, the Netherlands Elderly).

    Full summary, score breakdown and related studies → Original source

  21. 1996-11-01

    Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: We identified optimal staining methods for each of these and devised a protocol for the evaluation of cortical LB frequency based on a brain sampling procedure consistent with CERAD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 1996-11-01

    Cognitive and neurobiologic markers of early Alzheimer disease

    ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Recent studies indicate that impairments in two cognitive domains characterize the cognitive abnormalities that appear earliest in the course of Alzheimer disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

October 1996 1

  1. 1996-10-04

    Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

    ✓ Peer-reviewed Laboratory science Science

    Key finding: Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer beta-amyloid (Abeta) precursor protein containing a Lys670 --> Asn, Met671 --> Leu mutation had normal learning and memory in spatial reference and alternation tasks at 3 months of age but showed impairment by 9 to 10 months of age. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →