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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
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In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Variability in metabolic parameters and risk of dementia: a nationwide population-based study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's research & therapy 2018-10-27 Risk factors

    A total of 32,901 (1.12%) participants developed dementia, of which 74.4% and 11.0% were attributable to Alzheimer's disease and vascular dementia, respectively, during the median follow-up of 5.5 years.

  2. Cohort Profile Update: The Irish Longitudinal Study on Ageing (TILDA)

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. International Journal of Epidemiology 2018-07-14 End-of-life care

    As outlined in the original cohort profile,1 The Irish Longitudinal Study on Ageing (TILDA) is a prospective cohort study designed to provide an evidence base for addressing the challenges and opportunities associated with population ageing in Ireland.

  3. Comparison of Computerized and Paper-and-Pencil Memory Tests in Detection of Mild Cognitive Impairment and Dementia: A Systematic Review and Meta-analysis of Diagnostic Studies

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Journal of the American Medical Directors Association 2018-06-18 Cognitive tests and assessment

    Both verbal and visual computerized memory tests showed comparable diagnostic performance to the paper-and-pencil tests.

  4. Long-Lasting Neuropsychological Effects of a Computerized Cognitive Training in Patients Affected by Early Stage Alzheimer's Disease: Are They Stable Over Time?

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Journal of applied gerontology : the official journal of the Southern Gerontological Society 2018-01-02 Cognitive tests and assessment

    Patients in the experimental group showed a significant improvement in various neuropsychological domains due to the training, and these effects decreased after 12 months.

  5. Optimizing the preclinical Alzheimer's cognitive composite with semantic processing: The PACC5

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's & dementia (New York, N. Y.) 2017-11-10 Brain scans and imaging

    Addition of CAT to the PACC provides unique information about early cognitive decline not currently captured by the episodic memory, executive function, and global cognition components and may therefore improve detection of early Aβ-related cognitive decline.

  6. The Effect of Decreased Audibility on MMSE Performance: A Measure Commonly Used for Diagnosing Dementia

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Journal of the American Academy of Audiology 2016-04-01 Risk factors

    Apparent cognitive deficits based on MMSE scores obtained in test conditions in which audibility is reduced could result in incorrectly identified cognitive loss if clinicians are not alert to hearing loss when patients are evaluated.

  7. Smartphone-based detection of subtle memory decline in prodromal Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. NPJ digital medicine 2026-06-10 Cognitive tests and assessment

    The slow progression of Alzheimer's disease (AD) poses a challenge for the quantification of early disease-driven cognitive decline.

  8. Plasma Markers of Astrocytic and Axonal Integrity in Idiopathic/Isolated REM Sleep Behavior Disorder (iRBD) as Predictors of Dementia with Lewy Bodies

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Movement disorders : official journal of the Movement Disorder Society 2025-08-21 Biomarkers

    A total of 143 iRBD participants (110 male, 67.7 ± 8.0 years) were included.

  9. Association of white matter hyperintensities with cognitive decline and neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Frontiers in aging neuroscience 2024-09-12 Tau biomarkers

    Higher WMH volume was associated with older age, lower CSF amyloid-β levels, hypertension, and smoking history (all p ≤ 0.001), as well as cognitive status (MCI, p < 0.001; dementia, p = 0.008), but not with CSF tau levels.

  10. Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. JMIR aging 2024-06-26 Cognitive tests and assessment

    The CDR+NACC FTLD global score interacted with time on battery percentage such that participants with prodromal or symptomatic FTLD demonstrated less change in battery percentage throughout the day (a proxy for less smartphone use) than clinically normal participants (P<.001 in both cases).

  11. Plasma Aβ42/40 and cognitive variability are associated with cognitive function in Black Americans: Findings from the AA-FAIM cohort

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Alzheimer's & dementia (New York, N. Y.) 2023-09-25 Biomarkers

    IICV was associated with concurrent/baseline performance on several outcomes but did not modify associations between age and cognitive decline.

  12. Sensory impairment and beta-amyloid deposition in the Baltimore longitudinal study of aging

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2023-04-30 Risk factors

    The combinations of hearing and proprioceptive impairment and hearing, vision, and proprioceptive impairment, were positively correlated with cDVR (β = 0.087 and p = 0.036, β = 0.110 and p = 0.018, respectively).

  13. Associations between dietary patterns and dementia-related neuroimaging markers

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-03-24 Prevention and risk

    A high-protein and alcohol dietary pattern was negatively associated with cortical thickness in the whole brain (Beta: -0.011; 95% confidence interval [CI]: -0.018 to -0.003), and with an Alzheimer's disease cortical thickness signature score (Beta: -0.013; 95% CI: -0.024 to -0.001).

  14. Cardiovascular disease, associated risk factors, and risk of dementia: An umbrella review of meta-analyses

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Frontiers in epidemiology 2023-02-09 Risk factors

    Twenty-five meta-analyses published between 2007 and 2021 were included.

  15. Impact of the MIND Diet on Cognition in Individuals with Dementia

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Journal of Alzheimer's disease : JAD 2023 Prevention and risk

    The search generated 33 papers, which yielded 11 articles after screening.

  16. Aerobic Training and Circulating Neurotrophins in Alzheimer's Disease Patients: A Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Experimental aging research 2022-03-06 Prevention trials

    After 12 weeks, maintenance of executive functioning in the TG was found, yet no significant changes on circulating neurotrophins levels were identified.

  17. Effect of cognitive reserve on cognitive function in Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2022-03-01 Risk factors

    The present study showed that higher educational levels were related to better general cognitive function, executive function, memory, and information processing speed in PD patients, whereas no significant association was showed between educational levels and visuospatial function, language in PD patients.

  18. Association between the self-reported duration and quality of sleep and cognitive function among middle-aged and older adults in China

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Journal of affective disorders 2022-02-14 Risk factors

    Sleep duration had an inverted U-shape relationship with cognitive scores (P <.001); and sleep quality had a positive linear relationship with cognitive scores (P <.001).

  19. Slowing gait speed precedes cognitive decline by several years

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2022-02-09 Tau biomarkers

    Gait speed for participants who worsened in CDR score during follow-up was slower at most examinations.

  20. Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Systematic reviews 2022-01-06 Cognitive tests and assessment

    To the best of our knowledge, this will be the first systematic review and meta-analysis of narrowly defined CCT across clinical populations with depression.

  21. Repetitive Traumatic Brain Injury Among Older Adults

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The Journal of head trauma rehabilitation 2021-07-26 Costs and economics

    A total of 38 064 older Medicare beneficiaries experienced a TBI.

  22. Exercise interventions for older adults with Alzheimer's disease: a systematic review and meta-analysis protocol

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Systematic reviews 2021-01-04 Prevention trials

    This review is anticipated to yield clinically meaningful insight on the specific value of exercise for older adults with AD.

  23. Limbic-predominant age-related TDP-43 encephalopathy in Black and White decedents

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Neurology 2020-08-05 Brain tissue and pathology

    The overall frequency of LATE-NC in Black and White decedents was similar (40.8% vs 45.4%).

  24. Hearing Impairment and Cognitive Decline in Older, Community-Dwelling Adults

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2020-02-14 Risk factors

    Of 1,164 participants (mean age 73.5 years, 64% women), 580 (49.8%) had mild hearing impairment and 196 (16.8%) had moderate/severe hearing impairment.

  25. Motoric cognitive risk syndrome: Multicenter incidence study

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Neurology 2014-10-31 Digital health tools

    The incidence of MCR is high in older adults.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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