Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Explainable artificial intelligence (XAI) has gained much interest in recent years for its ability to explain the complex decision-making process of machine learning (ML) and deep learning (DL) models.
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The prospective cohort data from the JPSC-AD will provide valuable insights regarding the risk factors and etiology of dementia as well as for the development of predictive models and diagnostic markers for the future onset of dementia.
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Deep learning, a state-of-the-art machine learning approach, has shown outstanding performance over traditional machine learning in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision.
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When completed in 2022, Aging and Cognitive Health Evaluation in Elders study should provide definitive evidence of the effect of hearing treatment versus education control on cognitive decline in community-dwelling older adults with mild-to-moderate hearing impairment.
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72/100
In this cohort of older adults, increased numbers of optimal cardiovascular health metrics and a higher cardiovascular health score were associated with a lower risk of dementia and lower rates of cognitive decline.
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Retinal thickness is decreased in AD and MCI patients compared to HC.
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72/100
There has been growing evidence showing gait variability provides unique information about gait characteristics in neurological disorders.
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This is the first randomized controlled trial with supervised moderate-to-high intensity exercise in patients with mild AD.
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Our results corroborate the positive effect of pb-CT and its maintenance primarily on memory in HE and MCI participants that did not seem to be potentiated by RT.
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Longitudinal observational studies show an association between higher levels of physical activity and a reduced risk of cognitive decline and dementia.
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Fifty-nine primary studies met all criteria.
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The total effect of cholesterol on risk of AD was significant and heterogeneous.
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The search over five databases identified 898 articles, with 26 meeting the inclusion criteria.
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71/100
The cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain function is disrupted by pathology associated with aging and neurodegeneration.
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71/100
Alzheimer's disease is a common brain disorder affecting many people worldwide.
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Although computerized cognitive training (CCT) is an effective digital intervention for cognitive impairment, its dose-response relationship is understudied.
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Exercise training is an important strategy to counteract cognitive and brain health decline during aging.
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A smartphone application collected 2 modalities of cognitive data, digital voice and screen-based behaviors, from the FHS (Framingham Heart Study) multigenerational Generation 2 (Gen 2) and Generation 3 (Gen 3) cohorts.
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Thirty-one reviews were identified, sixteen of which were systematic reviews, and fifteen were meta-analyses.
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In the precuneus, we observed an inverted U-shaped pattern of novelty-related activity across groups, with higher activity in SCD and MCI compared with HC, but not in patients with AD who showed relatively lower activity than MCI.
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71/100
Polysomnography (PSG) studies of sleep changes in Alzheimer's disease (AD) have reported but not fully established the relationship between sleep disturbances and AD.
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71/100
We demonstrated that higher amyloid burden as measured by both CSF amyloid beta 42/40 ratio and non-displaceable binding potential in the posterior cingulate cortex was associated with lower functional connectivity in the default mode network.
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White matter deterioration is associated with cognitive impairment in healthy aging and Alzheimer's disease.
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Resting-state fMRI (rs-fMRI) detects functional connectivity (FC) abnormalities that occur in the brains of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI).
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71/100
HI and VI at baseline were reported by 30.3% and 16.6% of individuals, respectively.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- DTI measures in crossing-fibre areas: increased diffusion anisotropy reveals early white matter alteration in MCI and mild Alzheimer's disease
- Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases
- The Natural History of Alzheimer's Disease
- Repetitive negative thinking moderates the association between self-referential thoughts and cognition amongst older adults: a natural speech analysis approach
- The dementia of dementia praecox
- Neuropsychiatric symptoms as predictors of progression to severe Alzheimer's dementia and death: the Cache County Dementia Progression Study
- The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations
- In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
- Cognitive Control Network Homogeneity and Executive Functions in Late-Life Depression
- Joint association of cognitive reserve and frailty with incident Alzheimer's disease and related dementias