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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. A Mobile Application for Smart Computer-Aided Self-Administered Testing of Cognition, Speech, and Motor Impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Sensors 2020-06-06 Cognitive tests and assessment

    We present a model for digital neural impairment screening and self-assessment, which can evaluate cognitive and motor deficits for patients with symptoms of central nervous system (CNS) disorders, such as mild cognitive impairment (MCI), Parkinson's disease (PD), Huntington's disease (HD), or dementia.

  2. Classification and Visualization of Alzheimer’s Disease using Volumetric Convolutional Neural Network and Transfer Learning

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Scientific Reports 2019-12-03 Brain scans and imaging

    Recently, deep-learning-based approaches have been proposed for the classification of neuroimaging data related to Alzheimer's disease (AD), and significant progress has been made.

  3. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The Lancet. Neurology 2019-03-14 How common it is

    For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7.

  4. Disease progression timeline estimation for Alzheimer's disease using discriminative event based modeling

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. NeuroImage 2018-11-22 Digital health tools

    Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown.

  5. Convolutional Neural Networks-Based MRI Image Analysis for the Alzheimer's Disease Prediction From Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in neuroscience 2018-11-05 Digital health tools

    Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD).

  6. Size matters: Grey matter brain reserve predicts executive functioning in the elderly

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neuropsychologia 2018-08-10 Risk factors

    Preserved executive functioning (EF) is crucial for daily functioning in the elderly and it appears to predict dementia development.

  7. Overview of the clinical implementation of a study exploring social withdrawal in patients with schizophrenia and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neuroscience and biobehavioral reviews 2018-06-22 Cognitive tests and assessment

    Trans-diagnostic, domain- or symptom-focused approaches have been heralded as advancing psychiatric research, but relatively few clinical research programmes have been undertaken to leverage their potential.

  8. Brain age and other bodily 'ages': implications for neuropsychiatry

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Molecular psychiatry 2018-06-11 Genetics

    As our brains age, we tend to experience cognitive decline and are at greater risk of neurodegenerative disease and dementia.

  9. Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Scientific reports 2018-04-09 Digital health tools

    Alzheimer's Disease (AD) is a progressive neurodegenerative disease where biomarkers for disease based on pathophysiology may be able to provide objective measures for disease diagnosis and staging.

  10. Measuring cognition and function in the preclinical stage of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Alzheimer's & dementia (New York, N. Y.) 2018-02-13 Treatments

    The Alzheimer's Association's Research Roundtable met in November 2016 to explore how best to measure changes in cognition and function in the preclinical stage of Alzheimer's disease.

  11. A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Current Alzheimer research 2018-01-01 Digital health tools

    The temporal analysis of spontaneous speech can be exploited in implementing a new, automatic detection-based tool for screening MCI for the community.

  12. Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The Lancet. Neurology 2017-09-17 Risk factors

    The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions.

  13. Can a tablet-based cancellation test identify cognitive impairment in older adults?

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. PloS one 2017-07-24 Cognitive tests and assessment

    In the MCI group, age (B = -0.37, p<0.001) and current daily use of computer-based devices (B = 5.85, p<0.001) were associated with the number of correct cancellations of the e-CT.

  14. A neuroimaging approach to capture cognitive reserve: Application to Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Human brain mapping 2017-06-20 Risk factors

    Cognitive reserve (CR) explains interindividual differences in the ability to maintain cognitive function in the presence of neuropathology.

  15. Visual dysfunction and its correlation with retinal changes in patients with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Eye (London, England) 2017-03-10 Risk factors

    AimTo evaluate visual dysfunction and its correlation with structural changes in the retina in patients with Alzheimer's disease (AD).MethodsPatients with AD (n=24) and controls (n=24) underwent evaluation of visual acuity (VA), color vision (using the Farnsworth and L'Anthony desaturated (D) 15 color tests), and contrast sensitivity vision (CSV; using the Pelli-Robson chart and CSV-1000E test) to measure visual dysfunction.

  16. Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The journal of prevention of Alzheimer's disease 2017-01-01 Cognitive tests and assessment

    Preliminary findings suggest that the NIH Toolbox has the advantage of showing the strongest overall clustering and alignment with standardized paper-and-pencil tasks.

  17. Diagnostic Value of a Tablet-Based Drawing Task for Discrimination of Patients in the Early Course of Alzheimer's Disease from Healthy Individuals

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Cognitive tests and assessment

    There is a considerable delay in the diagnosis of dementia, which may reduce the effectiveness of available treatments.

  18. Computerized Structured Cognitive Training in Patients Affected by Early-Stage Alzheimer's Disease is Feasible and Effective: A Randomized Controlled Study

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2016-12-01 Cognitive tests and assessment

    Patients in the experimental group showed a significant improvement in various neuropsychological domains, and their achievements were stable after 6 months.

  19. Linguistic Features Identify Alzheimer's Disease in Narrative Speech

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2016-01-01 Digital health tools

    Modern machine learning and linguistic analysis will be increasingly useful in assessment and clustering of suspected AD.

  20. Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in aging neuroscience 2015-12-11 Brain scans and imaging

    We found that patients with T2DM exhibited cognitive function declines and functional connectivity disruptions within the default mode network, left frontal parietal network, and sensorimotor network.

  21. Alzheimer's disease progression by geographical region in a clinical trial setting

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Alzheimer's research & therapy 2015-06-25 Clinical trials

    Regions were heterogeneous at baseline. At baseline, disease severity as measured by ADAS-cog11, ADCS-ADL, and CDR-SB was numerically worse for Eastern Europe/Russia compared with other regions.

  22. Retinal ganglion cell analysis using high-definition optical coherence tomography in patients with mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Brain scans and imaging

    Our data strengthens the link between retinal ganglion cell neuronal and optic nerve axonal loss with AD, and suggest that assessment of macular GC-IPL can be a test to detect neuronal injury in early AD and MCI.

  23. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2015 Brain scans and imaging

    There was a significant association between greater Affective factor symptoms and reduced FPCN connectivity (p = 0.03).

  24. Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2011-08-20 Brain scans and imaging

    Regional functional connectivity (FC) of 39 patients with Alzheimer's disease (AD), 23 patients with mild cognitive impairment (MCI), and 43 healthy elderly controls was studied using resting-state functional magnetic resonance imaging (rs-fMRI).

  25. A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Annals of neurology 2010-10-01 Brain scans and imaging

    There is an urgent need for novel therapeutic approaches for AD.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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