Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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A blood-based screening tool can serve as a method for increasing access to state-of-the-art AD clinical research by bridging between community-based and clinic-based settings.
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These results indicate that declines in connected speech may be related to preclinical AD.
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The DelApp test showed good performance, supporting the utility of objectively measuring attention in delirium assessment.
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Combining multi-modality brain data for disease diagnosis commonly leads to improved performance.
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In this population-based longitudinal study, carotid IMT was associated with a higher risk of developing cognitive impairment during the 10-year follow-up, and was associated with poorer performance in a test of executive function 10 years later.
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The development of Alzheimer's disease (AD) later in life may be reflective of environmental factors operating over the course of a lifetime.
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Current knowledge of cognitive dysfunction in Parkinson's disease (PD) has largely been obtained from studies of chronically treated patients in whom effects of disease chronicity, treatment, depression and dementia are confounding factors.
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Individuals with autosomal dominant frontotemporal dementia (FTD) exhibit considerable variability in disease onset and progression.
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Sleep duration exhibited a U-shaped association with SPARE-AD (p = 0.001), Trail Making Tests A and B, and the Digit Symbol Substitution Test (all p < 0.001).
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Social isolation and loneliness are increasingly recognized as detrimental risk factors for brain health.
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The data of 1734 participants (1158 with AD, 105 with DLB, 46 with VaD, and 425 with CN) were analyzed.
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Participants with faster DunedinPACE had poorer cognitive functioning at baseline and experienced more rapid cognitive decline over follow-up.
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Greater educational attainment and mental activity were associated with higher composite SPPB scores and those of its three subtests (p < 0.05).
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61/100
Only the Aβ negative MCI group (MCI-Aβ-) was associated with depressive symptoms (odds ratio [OR] = 2.65, p = 0.005).
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61/100
Among 14,186 participants, we identified 1,194 (8.4%) who developed AD over a median follow-up period of 22.6 months.
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Elevated plasma neurofilament light chain (NfL) is associated with dementia though underlying mechanisms remain unknown.
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There was a significant interaction between PASE and MIND on executive functioning and total grey matter volume.
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Accumulation of beta-amyloid in the brain and cognitive decline are considered hallmarks of Alzheimer's disease.
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Regular physical activity was positively associated with CSF Aβ42 (p < 0.001) and Aβ42/40 (p < 0.001), while it was negatively associated with p-tau/Aβ42 (p < 0.001) and t-tau/Aβ42 (p < 0.001).
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61/100
These findings provide support for both the feasibility and validity of C3 and computerized cognitive outcomes more generally in AD secondary prevention trials.
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Poor speech-in-noise hearing (>-5.5-dB speech reception threshold; prevalence 14%) was associated with lower cognitive scores (ß = -1.28; 95% confidence interval [CI] -1.54 to -1.03).
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The mean age was 58.4 years (SD = 6.2). A 20-dB (equivalent to a one-category worsening) increase in HL was associated with a -1.53 (95% CI, -2.11, -0.94) raw score point difference in the DSST, adjusting for demographics, hearing aid use, and cardiovascular disease.
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Mean scaled scores in this longitudinal study were evaluated with repeated measures analysis of variance.
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The findings may help clinicians identify athletes who are at risk for worse impairments after a concussion due to preinjury sleep difficulties.
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Characterizing subtle cognitive changes in preclinical Alzheimer's disease (AD) is difficult using traditional neuropsychological assessments.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease
- Association Between Sensory Impairment and Dementia in Older Adults: Evidence from China
- Associations between physical performance and executive function in older adults with mild cognitive impairment: gait speed and the timed "up & go" test
- The Effectiveness of Computerized Cognitive Training Combined With Whole Body Cryotherapy in Improving Cognitive Functions in Older Adults. A Case Control Study
- Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging
- Smartphone for smart living: Using new technologies to cope with everyday limitations in semantic dementia
- Safety and efficacy of acupuncture for mild cognitive impairment: a study protocol for clinical study
- Altered Functional Connectivity of Hippocampal Subfields in Poststroke Dementia
- Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures
- Stroke Prevention