Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Light treatment alone did not improve nighttime sleep, daytime wake, or rest-activity rhythm.
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Stratification by self-reported recovery revealed that deficits were only detectable in SARS-CoV-2 positive individuals who did not feel recovered from COVID-19, whereas individuals who reported full recovery showed no deficits.
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Late-life depression is associated with significant cognitive impairment.
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Promising results are reported across nearly all 51 studies, but very few have been implemented in clinical research or practice.
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During the aging process, physical capabilities (e.g., muscular strength) and cognitive functions (e.g., memory) gradually decrease.
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There is a lack of midlife specific data, limited data on VaD, and a lack of geographical representation for many risk factors for dementia.
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Midlife insomnia (fully adjusted hazard ratio = 1.24, 95% confidence interval = 1.02-1.50) and late-life terminal insomnia (fully adjusted odds ratio = 1.94, 95% confidence interval = 1.08-3.49) were associated with a higher dementia risk.
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Baseline EDS was associated with increased longitudinal Aβ accumulation in elderly persons without dementia, suggesting that those with EDS may be more vulnerable to pathologic changes associated with Alzheimer disease.
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Low physical activity is associated with a higher risk for dementia in older individuals, suggesting that a reduced risk of dementia and higher brain volumes may be additional health benefits of maintaining physical activity into old age.
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The association of physical activity with dementia and its subtypes has remained controversial in the literature and has continued to be a subject of debate among researchers.
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This meta-analysis provides evidence that poor gait performance predicts dementia.
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Trajectories of systolic BP were separated markedly around 25 to 45 years of age, with the group below the median of cognition score having higher levels of systolic BP than the group above the median.
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Several studies suggest that physical activity improves cognitive functions and reduces cognitive decline, whereas others did not find any evidence of a neuroprotective effect.
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Cognitive impairment is recognised as an important non-motor symptom in Parkinson's disease (PD) and there is a need for evidence-based non-pharmacological interventions that may prevent or slow cognitive decline in this patient group.
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Evidence suggests that bilingualism may contribute to neuroplasticity and cognitive reserve, allowing individuals to resist cognitive decline associated with Alzheimer's disease progression, although the idea remains controversial.
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This study replicated research showing that education was positively associated with cognition at baseline.
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The BHA-CS was accurate at detecting cognitive impairment and exhibited excellent long-term stability.
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In the full cohort, 9.4% were diagnosed with major depression and 8.6% had chronically elevated depressive symptoms, both of which were related to adverse cognitive outcomes.
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Modifiable risk factors identified in this study, especially those with high-level evidence, should be considered in dementia prevention.
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Conventional neuropsychological assessments for Alzheimer's disease are burdensome and inaccurate at detecting mild cognitive impairment and predicting Alzheimer's disease risk.
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Dementia is a major contributor to dependence and disability in older people, with aging societies characterized by growing numbers of people living with the condition.
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IR is related to subsequent poorer cognitive performance and greater cognitive decline among patients with cardiovascular disease with and without diabetes.
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Androgen deprivation therapy in the treatment of prostate cancer may be associated with an increased risk of dementia.
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PSMD is a new, fully automated, and robust imaging marker for SVD.
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67/100
The findings of this study suggest an increased risk of dementia among individuals with TBI.