Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Age was similar between groups (p = 0.07).
Why it matters
This study found that older adults with mild cognitive impairment moved more slowly during a grocery shopping task than those without it, and that executive function explained much of this difference. It suggests wearable movement measures during real-world activities might serve as a marker, but it does not test a treatment or cure for Alzheimer's disease.
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These findings highlight potential access and quality-of-care issues in PR, with implications for Medicare Advantage benchmarks.
Why it matters
This study compared Hispanic Medicare beneficiaries with multiple complex chronic conditions, including dementia, in Puerto Rico and Florida, finding lower service use in Puerto Rico. It is about healthcare utilization and access, not about treating, curing, or preventing Alzheimer's disease.
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Participants racialized as Black living in a county with a history of lynching, disproportionate police killings, and disproportionate jail and prison incarceration were 2.8 (95%CI [-0.003, 5.834]) times more likely to have at least one incident of cognitive impairment between 2008-2020 compared to participants racialized as Black living in a county with a history of lynching and disproportionate police killings but not disproportionate incarceration.
Why it matters
This study found that Black participants living in a county with a history of lynching, disproportionate police killings, and disproportionate jail and prison incarceration were 2.8 times more likely to have at least one incident of cognitive impairment between 2008-2020. It suggests that enduring regional racial violence increases the chances of experiencing cognitive impairment among individuals racialized as Black.
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In adults aged ≥65 years, dementia with CAD was the cause of 1,256,284 deaths between 1999 and 2023.
Why it matters
This analysis of US death records found that dementia combined with coronary artery disease caused over 1.2 million deaths in people aged 65 and older between 1999 and 2023, with more than half occurring in long-term care. Overall death rates did not change significantly over time, but rural rates rose significantly while urban rates stayed stable.
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Among all evaluated models, the 3D-CNN and multimodal attention models achieved the highest performance, with accuracies of 84% and 86%, specificities of 83% and 86%, and sensitivities of 84% and 86%, respectively.
Why it matters
This study tested several deep learning models for classifying dementia from structural MRI scans, and the best models reached about 84-86% accuracy. However, all models showed reduced performance and bias toward certain classes, so these tools are not yet reliable enough for diagnosis and need better data representation and architecture.
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Dementia is a substantial public health issue with increasing prevalence globally.
Why it matters
This study developed a machine-learning model using tablet-based cognitive test data to classify clinical dementia ratings, with a deep learning model achieving high accuracy. It concerns automated classification for diagnosis and does not test any treatment, cure or prevention.
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Forty studies were included. Key stakeholders included healthcare professionals (HCPs); family members and caregivers; PWD; dyads (PWD and their caregivers); the broader public; policymakers; and researchers.
Why it matters
This review of 40 studies describes the needs of stakeholders involved in making advance care plans and directives for people with dementia. It does not test any treatment, cure or prevention.
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Informal caregivers often seek additional support.
Why it matters
This cost-consequence analysis found that the Partner in Balance caregiver program incurred significantly higher costs than usual care at 8 weeks, with better but not statistically significant caregiver utility scores. The authors state the study had too many limitations to make a confident reimbursement recommendation and recommend awaiting further research.
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This study examined how nursing home staff adapt to challenging mealtime behaviors in residents with dementia, such as turning away or refusing food.
Why it matters
This qualitative study examined how nursing home staff adapt to mealtime challenges in residents with dementia, suggesting that reframing feeding behaviors as communication may improve care. It addresses caregiving practices and does not test any treatment, cure or prevention for Alzheimer's disease.
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Following the pilot field test, a sustainability plan was co-developed with community facilitators to support continued implementation and ensure that resources spent on DWDAlter were not lost.
Why it matters
This pilot program adapted an existing dementia caregiving program for Black and faith communities, with 264 attendees, 95% of whom identified as Black or African American. Program acceptability was high, but evaluation of changes in caregiving self-efficacy and dementia knowledge will be conducted later.
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Efficient screening tools for cognitive decline and dementia are in high demand.
Why it matters
This clinical trial found that a tablet-based eye-tracking cognitive assessment correlated strongly with the Mini-Mental State Examination and was well tolerated. It supports the tool's utility for rapid cognitive screening, but it does not test any treatment, cure, or prevention for Alzheimer's disease.
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In 18,383 CM patients PS-matched to 18,383 dialysis patients, unadjusted Cox models showed dialysis transition was associated with higher risk of dementia, MCI, or combined dementia/MCI vs. CM: HRs (95%CIs) 1.40 (1.32-1.48), 1.64 (1.46, 1.85), and 1.42 (1.34, 1.49).
Why it matters
In this national cohort, patients with advanced chronic kidney disease who transitioned to dialysis had a higher risk of dementia or mild cognitive impairment than those managed conservatively. The study does not test any treatment, cure, or prevention for Alzheimer's disease.
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All dyads had at least one unmet need. A combined model incorporating predictors from both PWD and caregivers indicated that PLWD having lower education, being male, and exhibiting more neuropsychiatric symptoms are associated with more unmet needs.
Why it matters
In this study, all caregiver and person-with-dementia dyads had at least one unmet need, and unmet needs in the person with dementia were linked to factors in both the person and the caregiver. The authors say addressing both caregiver and patient needs through targeted support is essential.
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Why it matters
This study examined the acceptability and feasibility of a sensor-instrumented SmartSocks wearable prototype to detect agitation in people with dementia. It concerns monitoring a symptom and does not address treating, curing, or preventing Alzheimer's disease.
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Early and accurate diagnosis of dementia is essential to improving patient outcomes and reducing societal burden.
Why it matters
This study built a deep learning model using individual MMSE items to predict dementia and compared it with traditional machine learning models. It is a diagnostic prediction tool and does not address treating, curing or preventing Alzheimer's disease.
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Delirium is the most common neuropsychiatric syndrome encountered by clinicians caring for critically ill patients and is best characterized by five core domains: cognitive deficits, attentional deficits, circadian rhythm dysregulation, emotional dysregulation, and alteration in psychomotor functioning.
Why it matters
This review describes delirium in intensive care as common and linked to longer hospital stays, higher costs, more cognitive disorders including early onset dementia, and higher death rates. It stresses early detection with validated tools, non-drug interventions and cautious use of medication, but reports no cure or prevention for Alzheimer's disease.
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35/100
The participants controlled the EEG Switch above chance level across all tasks.
Why it matters
This study found that healthy adult participants could control an EEG-based switch above chance level, supporting its potential as a non-motor-dependent cognitive assessment tool. The study involved only healthy adults, so it is preliminary and does not yet show any use in treating, curing or preventing Alzheimer's disease.
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BackgroundPersons living with dementia (PLWD) on hospice care face unique end-of-life (EoL) care challenges.
Why it matters
This interview study of hospice medical directors found concern about caregiver burnout and hospice live discharge among persons living with dementia, since a larger proportion outlive the 6-month hospice eligibility requirement than other terminally ill patients. The directors suggested a dementia-specific hospice program, extending hospice benefit availability, and a step-down service for families experiencing live discharge.
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Despite an aging population and acknowledged importance of advance care planning (ACP) for persons living with cognitive impairment, few engage in ACP.
Why it matters
Interviews with 17 people with mild cognitive impairment or dementia and 15 caregivers identified 23 outcome categories for advance care planning, most of which were quality of life goals. It does not test any treatment, cure or prevention.
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35/100
In Mae Pa, the palliative care need prevalence was 2.03 per 1,000, among them, 84.62% had non-cancer conditions and 38.46% had neurodegenerative diseases with frailty and dementia.
Why it matters
This household survey in two rural Thai communities found palliative care need prevalence was highest among older adults and those with non-cancer conditions, including neurodegenerative diseases with frailty and dementia. The findings could help guide community-level palliative care development.
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The research findings revealed that 26.2% of the sample experienced psychological distress.
Why it matters
This study found that 26.2% of family caregivers of people with dementia experienced psychological distress, with perceived caregiver burden and perceived impact of behavioral and psychological symptoms significantly influencing distress. It concerns caregiver mental health and does not test any treatment, cure, or prevention for Alzheimer's disease.
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Reduced access to dementia healthcare services by elders from ethnic minority backgrounds is often a manifestation of underlying systemic disadvantages within dementia assessment and treatment services.
Why it matters
This narrative review describes reduced access to dementia healthcare and poorer treatment outcomes for UK ethnic minority elders, and proposes ways local systems may reduce these disadvantages. It is about inequalities in diagnosis, management, and long-term care, not about curing or preventing dementia.
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Emerging themes include (1) receptive to ACP, (2) mixed emotions, (3) barriers to ACP, (4) family consensus in decision-making, and (5) benefits of ACP.
Why it matters
This qualitative study in Hong Kong found family caregivers were open to advance care planning when initiated by the healthcare team, but faced emotional, cultural, and knowledge barriers. It concerns end-of-life planning and communication, not treating, curing, or preventing Alzheimer's disease.
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35/100
Age-related cognitive decline, characterized by memory loss, attention deficits, and reduced executive function, remains a major public health challenge, with limited pharmaceutical interventions offering symptomatic relief.
Why it matters
This review describes plant compounds such as flavonoids, curcumin, resveratrol, and Ginkgo biloba components that show antioxidant, anti-inflammatory, and other potentially protective effects in laboratory and some clinical studies. It notes challenges with bioavailability and dose, and states that large-scale clinical trials are still needed before these can be recommended.
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The early detection of dementia, a condition affecting both individuals and society, is essential for its effective management.
Why it matters
This study built a machine learning model using routine biochemical and physiological features from electronic health records to classify dementia, and it performed well on key metrics compared with other models. It is a model-development study, so it does not show that using this tool improves diagnosis or outcomes in real care.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Delirium in the emergency department: Incidence and risk factors in a Ligurian hospital
- Magnitude and Time-Course of Dementia Risk in Stroke Survivors
- Individualized prediction of clinical progression to dementia using plasma biomarkers in non-demented elderly
- Diabetes and dementia: current data
- A pilot study investigating the effectiveness, appreciation, and feasibility of a cognitive stimulation program in dementia patients: online versus face-to-face
- The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The Group for the Standardization of the Mental Deterioration Battery
- Advance Care Planning Billing Codes Associated With Decreased Healthcare Utilization in Neurological Disease
- The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features
- Hearing and cognitive scores measured with the Montreal Cognitive Assessment Scale in The HUNT Study, Norway
- The potential effects of meditation on age-related cognitive decline: a systematic review