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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. ESPEN Guidelines on Enteral Nutrition: Geriatrics

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Clinical nutrition (Edinburgh, Scotland) 2006-04-01 Clinical safety

    Nutritional intake is often compromised in elderly, multimorbid patients.

  2. The aging hippocampus: a multi-level analysis in the rat

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience 2006-03-29 Hippocampus size on brain scans

    In the current experiment we conducted a multi-level analysis of age-related characteristics in the hippocampus of young adult (3 months), middle-aged (12 months), and old (24 months) Fisher 344xBrown Norway hybrid (FBNF1) rats.

  3. Cognitive processes related to gait velocity: results from the Einstein Aging Study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychology 2006-03-01 Clinical safety

    The authors examined the relationship between cognition and gait velocity, performed with and without interference, in elderly participants.

  4. Biological markers of age-related memory deficits: treatment of senescent physiology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. CNS drugs 2006-01-01 Clinical safety

    In humans, age-related memory impairments begin in mid-life and cognitive weakening continues with advancing age.

  5. Family decision-making for nursing home residents with dementia: rural-urban differences

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association 2006-01-01 End-of-life care

    Most rural focus group participants voiced unqualified acceptance of death and placed few conditions on death, beyond their hope that it would be quick and peaceful.

  6. Cost-of-illness studies : a review of current methods

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. PharmacoEconomics 2006-01-01 Vascular contributions

    There was also evidence to suggest that the strengths and weaknesses of each method were considered when applying a method to a specific illness.

  7. Links between cognitive impairment in insulin resistance: an explanatory model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2005-10-24 Hippocampus size on brain scans

    Cognitive function and peripheral glucose regulation both decrease with age.

  8. Posttraumatic stress disorder: a state-of-the-science review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of psychiatric research 2005-10-18 Hippocampus size on brain scans

    This article reviews the state-of-the-art research in posttraumatic stress disorder (PTSD) from several perspectives: (1) Sex differences: PTSD is more frequent among women, who tend to have different types of precipitating traumas and higher rates of comorbid panic disorder and agoraphobia than do men.

  9. Reduced hippocampal volume among adolescents with alcohol use disorders without psychiatric comorbidity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Psychiatry research 2005-08-01 Hippocampus size on brain scans

    Studies have suggested that teens with alcohol use disorder (AUD) can demonstrate memory deficits, but the underlying neuroanatomical substrates are unclear.

  10. Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2005-07-14 Hippocampus size on brain scans

    Self-esteem, the value we place on ourselves, has been associated with effects on health, life expectancy, and life satisfaction.

  11. Work stress and physical assault of nursing aides in rural nursing homes with and without dementia special care units

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of psychiatric and mental health nursing 2005-06-01 Disparities

    There was a trend toward increased risk of being assaulted in the last year associated with being in a non-SCU facility.

    Why it matters

    This study compared nursing aides in rural nursing homes with and without dementia special care units. It found that those in special care units reported less exposure to disruptive behaviors and lower job strain, but it does not address treating, curing, or preventing Alzheimer's disease.

  12. The last days of life of nursing home patients with and without dementia assessed with the palliative care outcome scale

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Palliative medicine 2005-06-01 End-of-life care

    According to the NH staff, fairly good quality care was provided, but the psychosocial and spiritual aspects of care need to be addressed more in the last days of the dying NH patient's life.

  13. Palliative care for end-stage dementia: a discussion of the implications for education of health care professionals

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nurse education today 2005-05-01 End-of-life care

    The increasing burden of chronic disease demands that palliative care clinicians address the needs of patients with non-malignant disease.

  14. Pain and agitation in long-term care residents with dementia: use of the Pittsburgh Agitation Scale

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International journal of palliative nursing 2005-02-01 End-of-life care

    Study design descriptive correlational design.

  15. Strain experienced by caregivers of dementia patients receiving palliative care: findings from the Palliative Excellence in Alzheimer Care Efforts (PEACE) Program

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of palliative medicine 2004-12-01 End-of-life care

    Factor analysis of the Caregiver Strain Index revealed three dimensions of strain (role, personal, and emotional) related to caregiving.

  16. Alterations of neuroplasticity in depression: the hippocampus and beyond

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2004-12-01 Hippocampus size on brain scans

    Early hypotheses on the pathophysiology of major depression were based on aberrant intrasynaptic concentrations of mainly the neurotransmitters serotonin and norepinephrine.

  17. Smaller hippocampal volume in patients with recent-onset posttraumatic stress disorder

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2004-12-01 Hippocampus size on brain scans

    This result replicates previous findings of smaller hippocampal volumes in PTSD patients, but in an underinvestigated population, suggesting that either smaller hippocampal volume is a predisposing factor in the development of PTSD or that damage occurs within months of trauma, rather than a number of years.

  18. The human perirhinal cortex and semantic memory

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The European journal of neuroscience 2004-11-01 Hippocampus size on brain scans

    Studies in macaque monkeys indicate that the perirhinal cortex in the temporal lobe participates in object memory.

  19. Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the neurological sciences 2004-11-01 Vascular contributions

    Vascular cognitive impairment (VCI) was proposed as an umbrella term to include subjects affected with any degree of cognitive impairment resulting from cerebrovascular disease (CVD), ranging from mild cognitive impairment (MCI) to vascular dementia.

  20. Neuropsychological rehabilitation of memory deficits and activities of daily living in patients with Alzheimer's disease: a pilot study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2004-10-26 Prevention trials

    Patients with Alzheimer's disease (AD) gradually lose their cognitive competence, particularly memory, and the ability to perform daily life tasks.

  21. Spatial memory, recognition memory, and the hippocampus

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2004-09-27 Hippocampus size on brain scans

    There is wide agreement that spatial memory is dependent on the integrity of the hippocampus, but the importance of the hippocampus for nonspatial tasks, including tasks of object recognition memory is not as clear.

  22. Methods for assessment of cognitive failure and delirium in palliative care patients: implications for practice and research

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Palliative medicine 2004-09-01 End-of-life care

    The most commonly encountered clinical conditions presenting with cognitive failure (CF) are delirium, dementia and amnestic disorders.

  23. Forgoing artificial nutrition and hydration in nursing home patients with dementia: patients, decision making, and participants

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Alzheimer disease and associated disorders 2004-07-01 End-of-life care

    On the basis of these results, we recommend that discussions that include NHPs, family members, and nurses concerning decisions about possible future situations be held on a regular basis.

  24. Anatomical MRI study of borderline personality disorder patients

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Psychiatry research 2004-07-01 Hippocampus size on brain scans

    Hippocampal volume reduction has been reported in patients with borderline personality disorder (BPD), and is hypothesized to be associated with traumatic childhood experiences.

  25. The association between delirium and cognitive decline: a review of the empirical literature

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychology review 2004-06-01 Clinical safety

    Delirium is a common neurobehavioral syndrome that occurs across health care settings which is associated with adverse outcomes, including death.

From across this topic

10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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