Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Smart mobile and wearable technology offers exciting opportunities to support people with dementia (PwD).
Why it matters
This user-centred design case developed and tested assistive technology combining a smartphone, smartwatch, and applications with five end-users with dementia and their caregivers. Results showed some promise for user adoption but highlighted challenges to be overcome, emphasizing personalisation and familiarity as key considerations.
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Internet-based SLT using person-centered interventions provides a feasible model for delivering care to individuals with dementia and mild/moderate aphasia symptoms who have an engaged care-partner and prior familiarity with a computer.
Why it matters
This pilot feasibility study tested Internet-based speech-language therapy for people with progressive aphasia due to dementia, and reported functional gains and increased communication confidence at 2 months that were maintained at 6 months. It is a small feasibility study of a communication therapy, not a treatment, cure or prevention for Alzheimer's disease.
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End-of-life care for people with dementia does not differ from care throughout the dementia trajectory.
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There is strong evidence that diabetes mellitus increases the risk of cognitive impairment and dementia.
Why it matters
This review reports strong evidence that diabetes raises the risk of cognitive impairment and dementia, and that good blood sugar control may help prevent cognitive complications. It notes that anti-diabetic medications, especially insulin, may play a role in managing cognitive dysfunction, but says further investigation is needed to confirm this.
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The general practitioner (GP) is in a pivotal position to initiate and adapt care for their patients living with dementia.
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There is scarce information about the pathophysiological processes underlying Late-Life Depression (LLD).
Why it matters
In 44 people with late-life depression and 31 controls, a panel of three proteins discriminated the groups with 100% accuracy in this small sample. This is about understanding late-life depression biology, not Alzheimer's disease, and does not test any treatment, cure or prevention.
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The Interdisciplinary Care Leader role offers a promising method for supporting and improving end-of-life care discussions between families of people with advanced dementia and nursing home staff.
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GPs are identifying patients for anticipatory and palliative care more equitably across the different disease trajectories and earlier in the disease process than they were previously identifying patients specifically for palliative care.
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Of members initiated on an antimuscarinic OAB medication, 31.1% had a drug-drug or drug-disease or syndrome interaction.
Why it matters
This study examined potentially inappropriate antimuscarinic use for overactive bladder, finding dementia was the most common drug-disease interaction and that such use was linked to higher healthcare costs. It concerns medication safety in overactive bladder treatment rather than treating, curing or preventing Alzheimer's disease.
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Because of the growing size and aging of the world's population, the global burden of stroke is increasing dramatically.
Why it matters
This review is about stroke and transient ischemic attacks, not about treating, curing, or preventing Alzheimer's disease. It notes that many stroke risk factors are modifiable, but it does not report any Alzheimer's disease treatment or prevention result.
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Synaptic disruption is an early pathological sign of the neurodegeneration of Dementia of the Alzheimer's type (DAT).
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Dementia prevalence increases with age and Alzheimer's disease (AD) accounts for up to 75% of cases.
Why it matters
This review states that amyloid-clearing strategies have failed to provide benefits for Alzheimer's disease patients and argues research should broaden beyond amyloid. It reports no treatment, cure, or prevention of its own.
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In the present study we tested the cognitive effects of transcranial direct current stimulation (tDCS) in a case of probable Alzheimer disease (AD).
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This paper reviews empirical findings concerning the decision-making process of persons with dementia and their family carers, with a particular focus on the extent and determinants of involvement of persons with dementia in the decision-making process.
Why it matters
This review of 36 studies found that not all people with dementia are excluded from decision-making, but there is a broad spectrum of what counts as shared decision-making. It concerns care practices and does not test any treatment, cure, or prevention.
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There is enormous interest in designing training methods for reducing cognitive decline in healthy older adults.
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Driving simulator training offers the potential to enhance driving skills in older drivers.
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Evidence is accumulating which suggests that, in addition to leading to unprecedented rates of obesity, the current food environment is contributing to the development of cognitive impairment and dementia.
Why it matters
This review links the modern food environment, obesity and diets high in saturated fats and simple carbohydrates to cognitive impairment and dementia, and notes that many of these deficits involve inhibitory control over eating. Much of the supporting evidence comes from non-human animal research, so it does not yet show that changing diet prevents dementia in people.
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Only a minority of people with dementia receive a formal diagnosis despite a growing body of evidence highlighting the benefits of early diagnosis and intervention.
Why it matters
This review found that not enough has been done to address inequality in dementia service use for minority ethnic groups compared with the majority population. It reports no intervention with measurable outcomes, so it provides no evidence on treating, curing, or preventing Alzheimer's disease.
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The hippocampus, derived from medial regions of the telencephalon, constitutes a remarkable brain structure.
Why it matters
This review summarizes findings about how the hippocampus develops, including molecular signals that guide its formation. It is basic biology about brain development and does not test any treatment, cure, or prevention for Alzheimer's disease.
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The SHBM provides an empirically based conceptual framework for examining cross-cultural differences in dementia care-seeking among diverse groups.
Why it matters
This review found that minority ethnic older adults with dementia often had longer delays to diagnosis and more severe impairment at first evaluation, with barriers including lower acculturation, beliefs about memory loss, stigma and health system problems. It proposes a model to guide research and service planning rather than testing a treatment or cure.
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Neuropsychiatric symptoms such as agitation and delusions occur commonly in elderly patients with dementia and often cause significant distress.
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Based on the perceptions of bereaved family members, important opportunities exist to improve decision-making in feeding tube insertion.
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Ninety-four percent of hospices and 72% of PC programs had served at least one patient with a primary diagnosis of dementia within the past year.
Why it matters
This survey found that most hospices and many palliative care programs serve patients with dementia, and it identifies barriers such as lack of awareness and reimbursement policies. It does not test any treatment, cure, or prevention for Alzheimer's disease, and it suggests education and policy changes to improve palliative care.
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Patients with degenerative dementia often show language disorders, but little is known about their verbal (VC) and non-verbal communication (NVC).
Why it matters
This study described different patterns of verbal and non-verbal communication difficulties in patients with Alzheimer's disease, frontotemporal dementia, and dementia with Lewy bodies. It is about characterizing communication problems, not about treating, curing, or preventing Alzheimer's disease.
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Ethnic minority patients are seen on a regular basis in European dementia clinics.
Why it matters
This survey of European dementia centers found that most performed cognitive assessment with instruments validated only in Western cultures and that diagnostic evaluation of ethnic minority patients was considered challenging in 64% of centers. It describes clinical practice challenges and does not test any treatment, cure, or prevention.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- AI-delirium guard: Predictive modeling of postoperative delirium in elderly surgical patients
- Tai Chi Adapted: Assisted Living, Long-Term Care, and Nursing Homes
- The risk of delirium or dementia‐related hospitalization among individuals living with dementia after long‐term care entry: A population‐based risk prediction model
- Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study
- American Indian Caregivers Policy
- Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review
- Montreal Cognitive Assessment Arabic version: reliability and validity prevalence of mild cognitive impairment among elderly attending geriatric clubs in Cairo
- Changes in everyday function in individuals with psychometrically defined mild cognitive impairment in the Advanced Cognitive Training for Independent and Vital Elderly Study
- Neighborhood disadvantage and subjective cognitive function among older Black women
- Perspectives on artificial intelligence-enabled socially assistive robots in long-term care: Experiences with LOVOT among people with dementia and family caregivers