Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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37/100
Key reflections from advisor meetings guided cultural adaptation: lived experiences on dementia caregiving; patient, caregiver, and clinician interactions in the health care system; and limited knowledge and misconceptions of palliative care.
Why it matters
Hispanic/Latino caregiver advisors helped adapt dementia palliative care study materials for language, word choices, and recruitment. This is about making research more culturally inclusive, not about treating, curing, or preventing Alzheimer's disease.
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This study examines the challenges caregivers face in interpreting the bodily behaviors of individuals with late-stage dementia as interactional signals.
Why it matters
This study examines how caregivers interpret ambiguous non-verbal behaviors, called liminal signs, in people with late-stage dementia. It has practical implications for improving communication in dementia care, but it does not address treating, curing, or preventing the disease itself.
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What is already known about this topic?: As the Chinese population ages, the prevalence of cognitive impairment among older adults continues to increase.
Why it matters
Using nationally representative data from China, this report found that subjective cognitive decline and mild cognitive impairment among people aged 65 and older were common and clustered geographically. It provides information for targeting regional prevention and control efforts but does not test any treatment.
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Persons with disabilities (PWDs) are among the most at-risk groups during disaster situations due to various physical, sensory, cognitive, and systemic challenges that hinder their ability to prepare for, respond to, and recover from crises.
Why it matters
This study examines vulnerabilities and resilience of persons with disabilities during disasters and advocates for inclusive risk reduction policies. It contains no information relevant to Alzheimer's disease.
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Regression analysis identified three different models as predictors of caregiver burden.
Why it matters
This cross-sectional study found that caregiver depressive symptoms, distress from patient neuropsychiatric symptoms, and quality of life together predicted 52% of caregiver burden. It identifies factors linked to burden but does not show that changing them reduces burden, and the authors call for further research.
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The spectral analysis of the resting-state eyes-closed electroencephalographic (rsEEG) activity typically shows abnormal delta (< 4 Hz), theta (4-7 Hz), and alpha (8-12 Hz) power in older patients with cognitive deficits due to progressive neurodegenerative diseases.
Why it matters
This expert review recommends how to record and quantitatively analyze resting-state electroencephalography in prodromal and manifest dementia with Lewy bodies, noting that abnormally prominent posterior power below 8 Hz is considered a supportive diagnostic biomarker. It is about diagnosis, not treatment, cure or prevention.
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After 5 years, 666 (86.8%) individuals were followed up.
Why it matters
Over five years, older people carrying the ApoE ε4 allele, especially those aged 70-79, showed faster cognitive decline and a higher incidence of dementia. This confirms ApoE ε4 as a risk factor but does not provide a treatment or prevention.
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Among SNF admissions from 2013 to 2018, the share of ACO-attributed beneficiaries increased from 7.6% to 20.2%, MA enrollees increased from 25.2% to 32.8%, and non-ACO-attributed TM enrollees decreased from 67.2% to 47.3%.
Why it matters
This study found that Medicare beneficiaries in accountable care organizations were more likely to enter high-quality nursing homes than those in Medicare Advantage or traditional Medicare, regardless of dementia diagnosis. It highlights differences in access to quality nursing home care across payment models, but does not test any treatment, cure, or prevention for Alzheimer's disease.
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The findings from this study provide clear evidence that there is a greater need for resources to support SC residents with ADRD and their caregivers in the Pee Dee and Upstate regions.
Why it matters
This mapping study found that Alzheimer's disease and related dementias prevalence was concentrated in the Pee Dee and Upstate regions of South Carolina. The work is intended to guide resource allocation and inform future research, not to test any treatment, cure, or prevention.
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Retail workers contribute to the daily wellbeing of customers, including those living with disabilities or diseases.
Why it matters
This study looked at how convenience store workers' sense of social impact relates to their job satisfaction and turnover intentions as part of a dementia-friendly program. It is about retail workers' work outcomes and does not test any treatment, cure, or prevention for Alzheimer's disease.
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37/100
We enrolled 195 patients in the CARES dementia care program.
Why it matters
Among 195 patients enrolled in a dementia care program, 70.7% of completed POLST forms indicated do-not-attempt-resuscitation, with no significant difference between forms completed before versus after enrollment. This concerns end-of-life planning, not treating, curing or preventing Alzheimer's disease.
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We assessed the spatiotemporal patterns of hospitalization with comorbid cancer and dementia.
Why it matters
Using 2013-2018 Medicare claims, 22 hotspots with high hospitalization rates for people with co-present cancer and dementia were identified, with odds of being a hotspot increasing with the county-level percentage of dual Medicare-Medicaid beneficiaries and cancer prevalence. The study is about healthcare utilization patterns and resource allocation, not about treating, curing, or preventing Alzheimer's disease.
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Caregiving for a parent living with dementia (PLWD) shapes former caregivers’ personal health planning.
Why it matters
This qualitative study found that former caregivers of parents with dementia develop different outlooks that guide their own personal health planning. It does not test any treatment, cure, or prevention for Alzheimer's disease.
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Our study suggests that exposure to O3 is associated with the higher risk of dementia in American Indians.
Why it matters
In this study of 14,910 American Indians aged 65 and older, ozone exposure was significantly associated with dementia incidence, while associations with PM2.5 and CO were not statistically significant. The findings concern an environmental risk factor and do not test any treatment, cure, or prevention for Alzheimer's disease.
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Repeated measures analyses revealed no significant changes over time.
Why it matters
This pilot study of a home-based communication intervention for people with dementia and their caregivers found no significant changes over time. It is about communication support, not about treating, curing, or preventing Alzheimer's disease.
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To investigate the association of the area deprivation index (ADI), as assigned at the census block group-level, with progression to dementia in cognitively unimpaired at baseline participants (≥50 years old) of the population-based Mayo Clinic Study of Aging (MCSA).
Why it matters
This study looked at whether living in a more deprived area is linked to developing dementia in people who did not have it at the start. The provided text does not report any results, so no conclusion about this link can be drawn from it.
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What is already known about this topic?: Dementia leads public health issues worldwide.
Why it matters
This report describes geographic differences in hospital care, outcomes, and costs for dementia patients in China. It calls for policies to promote equitable resource allocation but does not evaluate any treatment, cure, or prevention for Alzheimer's disease.
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There are factors, other than the step changes in underlying cause of death coding, driving the progressively increasing temporal trend in relative risk of dementia‐associated death.
Why it matters
This study used Scottish death records to model geographic and time trends in dementia-associated deaths. It is about mortality data and coding, not about treating, curing or preventing Alzheimer's disease.
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A significantly higher percentage of DRP patients had ≥1 diagnosis for behavioral health conditions in the pre-index period compared with dementia-only patients (depression: 32.4% vs. 22.8%; anxiety: 19.1% vs. 11.5%; and insomnia: 9.0% vs. 6.3%; P < 0.001 for all comparisons).
Why it matters
This study found that patients with dementia-related psychosis had significantly higher rates of behavioral health conditions, clinical events, healthcare utilization, and costs compared with dementia-only patients. It concluded that understanding the burden of illness among patients with dementia-related psychosis is important.
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OF IMPACT: The results contribute new evidence towards an emerging ecological model of cognitive health.
Why it matters
This study examined whether access to coffee shops and fast-food restaurants is linked to cognitive function in older Americans, using interviews and national data. It is early work on neighborhood resources and does not test any treatment, cure, or prevention for Alzheimer's disease.
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fewer functional limitations in the MA population, perhaps explaining why those patients had fewer health care visits.
Why it matters
This commentary discusses differences in care between Medicare Advantage and traditional Medicare for patients with Alzheimer's disease and related dementias. It does not test any treatment, cure, or prevention, and it calls for more research to understand the implications of managed care for these patients.
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Residence in a food desert (11·1 %, n 411) was not significantly associated with perceived access to healthy foods, most grocery shopping behaviours or dietary behaviour, but was significantly associated with primarily shopping at a superstore or supercentre v . a large grocery store (OR = 1·32; 95 % CI 1·02, 1·71; P = 0·03) and higher BMI ( b = 1·14; 95 % CI 0·36, 1·93; P = 0·004).
Why it matters
This study compares food desert residents with non-food desert residents on shopping, diet and BMI, not Alzheimer's disease, so it provides no information on treating, curing or preventing Alzheimer's. It found food desert residence was linked to shopping at superstores and higher BMI.
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Neuroimaging provides a window on the biological events underlying dementia.
Why it matters
This review describes how amyloid PET, tau PET, MRI, FDG PET and inflammation PET can help distinguish causes of dementia and track progression. It notes some techniques are still investigational and does not report any treatment, cure or prevention.
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Opioid use was significantly higher in females and Whites and varied by states.
Why it matters
This cohort study describes trends in opioid use among long-term care nursing home residents with dementia. It provides no information on treating, curing or preventing Alzheimer's disease itself.
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The annual number of deaths at hospital was consistently increased over time from 1996 to 2016 (age-adjusted OR: 6.01; 95% CI 5.81 to 6.21 versus home deaths).
Why it matters
This observational study of national death certificates found that, after the national dementia plan, deaths from dementia were more likely to occur in hospital, intermediate geriatric care facilities or nursing homes rather than at home. It suggests that improving the availability of palliative and end-of-life care where patients live could help change this pattern.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Impact of Conservative Management vs. Dialysis Transition on Cognition in a National Cohort of Patients with Advanced CKD
- Feasibility and Acceptability of Implementing a Digital Cognitive Assessment for Alzheimer Disease and Related Dementias in Primary Care
- Health benefits of physical activity in older patients: a review
- Factors Associated With Emergency Department Visits by People With Dementia Near the End of Life: A Systematic Review
- Revised recommendations on standards and norms for palliative care in Europe from the European Association for Palliative Care (EAPC): A Delphi study
- Research attitudes in families of individuals with Down syndrome: importance for clinical trials
- Advocacy and Palliative Care as a Framework for Dignified Dementia Care in African Settings
- Independent predictors of cognitive decline in healthy elderly persons
- Dementia in Rare Genetic Neurodevelopmental Disorders: A Systematic Literature Review
- Timing and risk factors for functional changes associated with medical hospitalization in older patients