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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Racial disparities in medication use: imperatives for managed care pharmacy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Managed Care & Specialty Pharmacy 2020-10-29 Health systems and care delivery

    The COVID-19 pandemic and the social unrest pervading U.S. cities in response to the killings of George Floyd and other Black citizens at the hands of police are historically significant.

    Why it matters

    This commentary discusses racial disparities in medication use and adherence, noting that adherence rates have been documented to be lower among Black patients compared with White patients even when cost sharing is minimal or zero. It does not test any treatment, cure, or prevention of Alzheimer's disease.

  2. Stalling life expectancy and increased mortality in working ages deserve urgent attention

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Lancet Public Health 2019-11-01 Risk factors

    The effect of austerity and associated budgets are strong contenders,3Ruckert A Labonté R Health inequities in the age of austerity: the need for social protection policies.

    Why it matters

    This paper discusses stalling life expectancy and increased mortality in working ages, noting that austerity and associated budgets are strong contenders for the effect. It also notes that examining neighbourhood effects over the life course suggests that where you have been and are currently living underpins developing inequalities.

  3. Demands for Development of Taurine-Containing Home Meal Replacement for Prevention of Dementia According to Age

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Advances in experimental medicine and biology 2019-08-31 Risk factors

    It has been reported that taurine intake in the past may have a positive effect on present cognitive function in the elderly.

    Why it matters

    This survey in Korea found that middle-aged adults had a higher need for elderly-friendly meal replacements than older adults, but interest in a taurine-containing meal replacement for dementia prevention was lower in the middle-aged groups. It is a survey of consumer preferences and does not test whether taurine prevents dementia.

  4. Artificial intelligence as an emerging technology in the current care of neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurology 2019-08-26 Digital health tools

    The smart device system to monitor tremors and to recognize its phenotypes for better outcomes of deep brain stimulation, applications evaluating fine motor functions, AI integrated electroencephalogram learning to diagnose epilepsy and psychological non-epileptic seizure, predict outcome of seizure surgeries, recognize patterns of autonomic instability to prevent sudden unexpected death in epilepsy (SUDEP), identify the pattern of complex algorithm in neuroimaging classifying cognitive impairment, differentiating and classifying concussion phenotypes, smartwatches monitoring atrial fibrillation to prevent strokes, and prediction of prognosis in dementia are unique examples of experimental utilizations of AI in the field of neurology.

    Why it matters

    This review describes how artificial intelligence is being applied to monitor and diagnose neurological disorders, including cognitive impairment. It is a general overview and does not report testing of any treatment, cure or prevention for Alzheimer's disease.

  5. Impact of support agreement between municipalities and convenience store chain companies on store staff's support activities for older adults

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Health policy (Amsterdam, Netherlands) 2018-10-10 Risk factors

    In the continuously aging society, private sectors are expected to play a role in older adult care.

    Why it matters

    Convenience stores that had a support agreement with their municipality had more staff activities like attending dementia support lectures and collaborating with community support centers. This is about community support services, not about treating, curing, or preventing Alzheimer's disease.

  6. The “American (cancer) patients first” plan to reduce drug prices—A critical assessment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. American Journal of Hematology 2018-09-16 Health systems and care delivery

    Serious concerns over the rising cost of cancer drugs in the United States1-3 are increasing,4-9 following a decade during which prices rose from an average of less than $10 000/year to more than $170 000/year in 2017.10 Despite the drug industry's wish to be “part of the solution,” the problem continues to worsen.6 Between 1995 and 2013, the launch price of cancer drugs increased by 10%-12% every year.11 According to a March 2018 report, the Average Wholesale Prices of drugs increased at unprecedented rates.12 A study by Gordon and colleagues showed a 25% average annual price increase of drugs already on the market, despite competition.13 Cancer drugs spending doubled since 2013 and is expected to double again by 2022.14 This suggests that health care is different from other industries where traditional free market forces are effective in lowering prices, and that other measures are needed.

    Why it matters

    This paper critically assesses a plan to reduce cancer drug prices in the United States. It contains no information about treating, curing, or preventing Alzheimer's disease.

  7. An Interprofessional Virtual Healthcare Neighborhood: Effect on Self-Efficacy and Sleep Among Caregivers of Older Adults With Dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of gerontological nursing 2016-11-01 Risk factors

    An Interprofessional Virtual Healthcare Neighborhood (VHN) was designed to deliver information, peer support, and professional guidance to caregivers of individuals with dementia.

    Why it matters

    This small study of 28 caregivers found no significant changes in sleep quality or quantity in either the group using the virtual support program or the usual-care group. It does not test any treatment, cure, or prevention for Alzheimer's disease itself.

  8. Psychoradiology: The Frontier of Neuroimaging in Psychiatry

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Radiology 2016-11-01 Vascular contributions

    Unlike neurologic conditions, such as brain tumors, dementia, and stroke, the neural mechanisms for all psychiatric disorders remain unclear.

  9. MRI uncovers disrupted hippocampal microstructure that underlies memory impairments after early-life adversity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Hippocampus 2016-10-11 Hippocampus size on brain scans

    Memory and related cognitive functions are progressively impaired in a subgroup of individuals experiencing childhood adversity and stress.

  10. Do "Brain-Training" Programs Work?

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Psychological science in the public interest : a journal of the American Psychological Society 2016-10-01 Prevention trials

    How could two teams of scientists examine the same literature and come to conflicting "consensus" views about the effectiveness of brain training?

  11. Benzodiazepine Misuse in the Elderly: Risk Factors, Consequences, and Management

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current psychiatry reports 2016-10-01 Clinical safety

    Benzodiazepine (BZD) inappropriate use (i.e., misuse and overuse) is a worldwide public health problem.

  12. Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks Contributes to Youthful Memory in Superaging

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2016-09-01 Hippocampus size on brain scans

    We defined superagers (60-80 years old) based on their performance compared to young adults (18-32 years old) on the California Verbal Learning Test Long Delay Free Recall test.

  13. Estimated Budget Impact of Increased Use of Mirabegron, A Novel Treatment for Overactive Bladder

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Managed Care & Specialty Pharmacy 2016-08-31 Health systems and care delivery

    Primary analysis calculated the impact of increasing the use of mirabegron from 4.5% to 5.3%, 7.1%, and 9.4% in years 1, 2, and 3, respectively, among oral pharmacological OAB treatments that included generic and branded antimuscarinics: oxybutynin, tolterodine, trospium, darifenacin, fesoterodine, and solifenacin.

    Why it matters

    This study estimated the budget impact of increasing use of mirabegron for overactive bladder. It concerns overactive bladder treatment costs, not Alzheimer's disease, so it has no implications for treating, curing or preventing dementia.

  14. Differential association of left and right hippocampal volumes with verbal episodic and spatial memory in older adults

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychologia 2016-08-16 Hippocampus size on brain scans

    The hippocampus plays a critical role in verbal and spatial memory, thus any pathological damage to this formation may lead to cognitive impairment.

  15. 'Failure to Maintain': A theoretical proposition for a new quality indicator of nurse care rationing for complex older people in hospital

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International journal of nursing studies 2016-08-10 Clinical safety

    This privileging, also known as implicit rationing, is theoretically and physiologically associated with a rise in the incidence of complications such as pressure injuries, pneumonia, urinary tract infection, and delirium.

  16. Pain in Hospice Patients With Dementia: The Informal Caregiver Experience

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. American journal of Alzheimer's disease and other dementias 2016-06-14 End-of-life care

    Our findings indicate the possible need for increased support for caregivers, including educational interventions targeting pain etiology and assessment, and improved communication with health-care professionals.

  17. Prevalence of Artificial Food Colors in Grocery Store Products Marketed to Children

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Clinical Pediatrics 2016-06-06 Risk factors

    Artificial food colors (AFCs) in foods and beverages may be harmful to children.

    Why it matters

    This study measures artificial food colors in grocery products marketed to children, not Alzheimer's disease, so it offers nothing on treating, curing or preventing Alzheimer's. It found that 43.2% of such products contained artificial food colors.

  18. Cognition and gait in older people

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Maturitas 2016-05-10 Prevention trials

    Cognitive difficulties and gait abnormalities both increase with age.

  19. Dysphagia, dystussia, and aspiration pneumonia in elderly people

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of thoracic disease 2016-03-01 Clinical safety

    Despite the development and wide distribution of guidelines for pneumonia, death from pneumonia is increasing due to population aging.

  20. Brain fluorodeoxyglucose (FDG) PET in dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Ageing research reviews 2016-02-11 Disease mechanisms

    The purpose of this article is to present a selective and concise summary of fluorodeoxyglucose (FDG) positron emission tomography (PET) in dementia imaging.

  21. Management of psychiatric and neurological comorbidities in epilepsy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Neurology 2016-01-18 Vascular contributions

    The treatment of epileptic seizure disorders is not restricted to the achievement of seizure-freedom, but must also include the management of comorbid medical, neurological, psychiatric and cognitive comorbidities.

  22. The rise in the ageing population has resulted in increased incident rates of cognitive impairment and dementia.

  23. Cognitive impairment in Parkinson's disease and dementia with Lewy bodies

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Parkinsonism & related disorders 2015-09-21 Prevention trials

    Parkinson's disease (PD) and dementia with Lewy bodies (DLB) share clinical and pathological similarities.

  24. Family physicians' role in palliative care throughout the care continuum: stakeholder perspectives

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Family practice 2015-09-14 End-of-life care

    Our results help to elucidate the tasks and roles required of FPs to make integration of a palliative care approach into the care continuum possible.

  25. Tauopathies as clinicopathological entities

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Parkinsonism & related disorders 2015-09-08 Disease mechanisms

    Tauopathies are a class of neurodegenerative disorders characterized by neuronal and/or glial inclusions composed of the microtubule-binding protein, tau.

From across this topic

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