Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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The results of the inverse variance weighted analysis demonstrate a significant positive causal relationship between stroke and VaD (OR = 2.06, 95% confidence interval [CI] = 1.17-3.61, P = .01).
Why it matters
Using genetic analysis, this study found evidence that stroke may causally raise the risk of vascular dementia, but found no evidence that vascular dementia raises stroke risk. It also identified shared biological targets between the two conditions, pointing to possible mechanisms but not yet to a treatment.
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Using data from South Korea’s 2018 teleconsultation pilot program involving 1232 patients, the analysis revealed that teleconsultation reduced societal costs per consultation by USD 7.92 for chronic diseases, USD 27.30 for dementia care, and USD 9.61 for rehabilitation.
Why it matters
Using data from a South Korean teleconsultation pilot, teleconsultation reduced societal costs per consultation for dementia care by USD 27.30, mainly through lower productivity losses and transportation expenses. This is about cost and access to care, not about treating or preventing the disease itself.
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The increased consumption of fruit and vegetables is essential for moving towards a healthier and more sustainable diet.
Why it matters
This review discusses pesticide residues in plant-based foods and calls for sustainable agriculture to reduce contamination. It contains no information relevant to Alzheimer's disease.
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"Sundowning syndrome" refers to the evening decline in mental state among cognitively impaired patients.
Why it matters
This article discusses sundowning syndrome in dementia, noting that its development relies on neurodegeneration, sleep disorders, circadian rhythm, and mood disorders, and that behavioral interventions are more efficacious but require intense caregiver involvement. It is a discussion of mechanisms, diagnosis, and treatment approaches for sundowning rather than a test of treating, curing, or preventing Alzheimer's disease.
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Frontotemporal dementia (FTD) encompasses a group of heterogeneous neurodegenerative disorders.
Why it matters
This review discusses diagnostic tools for frontotemporal dementia, including blood-based biomarkers and functional neuroimaging, and notes that emerging disease-modifying therapies require early patient enrollment. It concerns frontotemporal dementia rather than Alzheimer's disease and reports no treatment, cure or prevention.
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The mean (SD) age of PWD was 81 (8.1) years; 45% were women, 33% Black, and 15% Hispanic.
Why it matters
This pilot study found that eliciting medication-related priorities of people with dementia and their care partners can support goal-concordant care, with pharmacists recommending both deprescribing and prescribing. It does not test whether this approach prevents or cures Alzheimer's disease.
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Fifteen experts, with a mean professional experience of 25 ± 10 years, reached a consensus in the fourth round.
Why it matters
A panel of experts estimated that dementia affects about 1 in 12 Brazilians aged 60 and over, with higher rates in women and regional variation, and projected cases would rise to 8.89 million by 2060. These are consensus estimates meant to guide public health planning, not findings about treatment or prevention.
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43/100
Despite progress in involving people living with dementia in health research, disparities remain, particularly in the field of health economics and outcomes research, where excessive reliance on proxy reports from care partners or healthcare professionals persists even when people are capable of self-reporting, leading to inequitable inclusion.
Why it matters
Interviews with 23 people with mild to moderate dementia showed they define a 'good life' through independence, social connections, engagement, and adaptation as abilities change. The study found gaps between these lived experiences and current preference-based outcome measures, which matters for how quality of life is assessed, not for curing or preventing dementia.
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Here we show, psychiatric behavioural symptoms and difficulties in activities of daily living, fluctuate alongside cognitive decline. 677 activities of daily living and 632 psychiatric behaviour questionnaires are available at intervals of 3 months.
Why it matters
Using in-home assessment data, this study found that psychiatric behavioural symptoms and difficulties in activities of daily living fluctuate alongside cognitive decline in people living with dementia. It offers insights into care needs and behavioural changes but does not test any treatment, cure or prevention.
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The study population consisted of 54 million Medicare data Fee-for-Service (FFS) and Medicare Advantage enrollees aged ≥ 65; 5.3 million beneficiaries were diagnosed with ADRD, and 16.2% (n = 861,337) of beneficiaries diagnosed with ADRD resided in rural America.
Why it matters
This report describes how many Medicare beneficiaries aged 65 and older were diagnosed with Alzheimer's disease and related dementias in rural versus other areas of the United States in 2020. It does not test any treatment, cure, or prevention.
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<0.001), with key domain correlations ≥0.7 (language, memory, executive).
Why it matters
This cross-sectional study found the tablet-based Seoul Cognitive Status Test showed good diagnostic accuracy for distinguishing cognitively unimpaired people from those with mild cognitive impairment or dementia. The authors state further studies in broader community-based cohorts are needed to confirm generalisability; it concerns assessment, not treatment or cure.
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The rising prevalence of Alzheimer's disease and Alzheimer's disease–related dementias has led to renewed public discourse and policy changes in response to the care needs of persons living with dementia and their care partners.
Why it matters
This review describes the current state of comprehensive dementia care models in the United States and related policies, including the Centers for Medicare & Medicaid Services Guiding an Improved Dementia Experience model. It outlines challenges and opportunities for nursing research and implementation, but does not report new results on treating, curing or preventing Alzheimer's disease.
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Mild cognitive impairment (MCI) is an early stage of non-age-related cognitive decline with an increased risk of progressing to dementia.
Why it matters
This review looks at EEG and ERP brain-activity tests combined with machine learning as ways to detect mild cognitive impairment, which can be an early stage before dementia. It is a review of methods, not a treatment or cure, and it notes that noise, differences between people, and difficulty interpreting the models still limit reliability.
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Mild cognitive impairment (MCI) is a condition characterized by noticeable deficits in memory retrieval or other cognitive domains than the individuals with the same age but do not significantly interfere with daily functioning.
Why it matters
Current evidence suggests transcranial direct current stimulation provides short-term cognitive benefits in mild cognitive impairment, particularly in memory and attention, with inconsistent effects on executive function and language. Long-term efficacy remains uncertain due to limited longitudinal research and short follow-up periods.
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Medical coding impacts patient care quality, payor reimbursement, and system reliability through the precision of patient information documentation.
Why it matters
This study used administrative claims data to build a metric for how specifically dementia diagnoses are coded at hospitals, not to test any treatment or prevention. It does not show anything about curing or preventing Alzheimer's disease; it is about billing and documentation accuracy.
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Before the COVID-19 pandemic, supply and demand forcast models predicted significant nursing shortages across the United States through 2030 due to both an aging patient population and nursing workforce.1, 2 However, during the pandemic, we saw an exodus of younger nurses in addition to early retirements.
Why it matters
This article discusses nursing shortages and workforce disruptions contributing to patients remaining in hospitals, especially related to post-acute care placement. It does not address treating, curing, or preventing Alzheimer's disease.
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Participants racialized as Black who lived in places with higher levels of area‐level structural socioeconomic racism experienced lower levels of cognition at baseline and at varying time points in the six‐year period—compared to those in places with lower structural socioeconomic racism.
Why it matters
This study found that Black participants living in places with higher area-level structural socioeconomic racism had lower cognition at baseline and at varying time points over a six-year period. It highlights the utility of examining how racist U.S. policies enacted in the past and present influence health over time.
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Approximately half of the sample were persistently food secure, 17% became food secure, 14% became FI, and 15% experienced persistent FI.
Why it matters
This study found that persistent food insecurity was linked to worse performance on several thinking tests, and that depressive symptoms partly explained the link to poorer verbal recall. It suggests stable food access may be a modifiable factor for cognitive outcomes, but it does not test a treatment or cure for Alzheimer's disease.
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Neurological diseases cause physical, psychosocial, and spiritual or existential suffering from the time of their diagnosis.
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Neurodegenerative diseases have reached alarming numbers in the past decade.
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Family caregivers of nursing home residents with dementia received an educational booklet and a family care conference with a trained facilitator to discuss their relative's future care.
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Certain diets, such as the Mediterranean diet, may play a significant role in healthy aging by preventing the onset of certain diseases and by improving the aging process itself.
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43/100
The percentage of new enrollees with an ADRD code dropped significantly during the months of IMPACT passage (-1.42 percentage points; 95% CI, -2.13 to -0.71) and implementation (-1.98 percentage points; 95% CI, -2.70 to -1.26) but rose again during the following months.
Why it matters
This study found that recent Medicare hospice policy changes were associated with immediate and lasting reductions in the share of hospice patients with an Alzheimer's disease and related dementias code. It is about hospice enrollment patterns and policy, not about treating, curing, or preventing Alzheimer's disease.
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Chronic conditions such as obesity, diabetes, and dementia are increasing in the United States (US) population.
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The Mediterranean diet is a plant-based, antioxidant-rich, unsaturated fat dietary pattern that has been consistently associated with lower rates of noncommunicable diseases and total mortality, so that it is considered one of the healthiest dietary patterns.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Pathways linking late-life depression to persistent cognitive impairment and dementia
- Converting short cognitive screen scores: Comparing the Quick mild cognitive impairment screen, Montreal cognitive assessment, and Mini-mental state examination
- Understanding barriers and optimizing socio‐cognitive assessment in the diagnosis of neurocognitive disorders
- Using consumer wearables to estimate physical activity of nursing home residents with dementia
- 205 PHYSICAL ACTIVITY MODULATES GEOGRAPHICAL VARIATIONS IN COGNITIVE AGEING: RESULTS FROM THE IRISH LONGITUDINAL STUDY ON AGEING
- Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study
- A claims data-based comparison of comorbidity in individuals with and without dementia
- Emotional impact of dementia diagnosis: exploring persons with dementia and caregivers' perspectives
- Association of small vessel disease progression with longitudinal cognitive decline across mild cognitive impairment
- A review of studies on vascular dementia and iron metabolism