Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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43/100
Cognitive dysfunctions such as mild cognitive impairment (MCI), Alzheimer's disease (AD), and other forms of dementia are recognized as common comorbidities of type 2 diabetes mellitus (T2DM).
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Among beneficiaries sampled by CAHPS, 22.2% with ADRD completed the survey compared to 38.5% without ADRD.
Why it matters
This study found that Medicare Advantage beneficiaries with Alzheimer's disease and related dementias reported worse care experiences in receiving needed care and in customer service than those without dementia, whether responses came from proxies or non-proxies. Beneficiaries with dementia were also more likely to be excluded from survey performance measures and had higher non-response rates.
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Engagement in advance care planning might be hindered if it is too medicalized and exclusively patient-centered.
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Tai Chi enhanced cognitive training effects in MCI.
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Atrial fibrillation already accounts for a significant amount of National Health Service (NHS) funding, and over the coming years is highly likely to impose a growing cost on NHS budgets and the wider UK healthcare system.
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The current nosological concept of α-synucleinopathies characterized by the presence of Lewy bodies (LBs) includes Parkinson's disease (PD), Parkinson's disease dementia (PDD), and dementia with Lewy bodies (DLB), for which the term "Lewy body disease" (LBD) has recently been proposed due to their considerable clinical and pathological overlap.
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Associations of neighbourhood NO2 level, walkability, public open space and social fragmentation with dementia incidence and estimated future risk of dementia were statistically significant, indicating the potential to reduce the risk through changes in built and social environments.
Why it matters
In 25,511 patients aged 65 and older in Adelaide, a one standard deviation increase in nitrogen dioxide and walkability score was associated with 10% higher odds of any versus no dementia, and increases in social fragmentation and nitrogen dioxide were associated with a 1% increase in estimated future dementia risk. The study is about environmental associations with dementia incidence and risk, not about treating, curing, or preventing Alzheimer's disease.
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The first WHO guidelines for risk reduction of cognitive decline and dementia marked an important milestone in the field of dementia prevention.
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Key independent variables included the interaction of NH quality (measured by 5‐star rating) and race (i.e. black versus white), and interaction of NH quality, race, and state Medicaid dementia‐related add‐on policies.
Why it matters
This study examined racial differences in admissions to high-quality nursing homes and how state Medicaid dementia-related add-on policies affected them. It concerns care access, not treating, curing, or preventing Alzheimer's disease.
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A digitally delivered intervention with minimal support appears acceptable and potentially engaging to older adults with higher and lower levels of cognitive performance.
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Many studies have associated the Mediterranean diet with a decreased risk of dementia and AD, but a cause-and-effect relationship has not been deduced.
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SNfL was perceived as useful in 53% (n = 58) of the cases.
Why it matters
In 109 people visiting a memory clinic, neurologists found serum neurofilament light useful in 53% of cases, and the authors recommend it to confirm or exclude neurodegeneration in people under 62 and in males. This is about using a biomarker in practice, not about treating, curing or preventing Alzheimer's disease.
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43/100
Increasing age (especially >60 years) may be the most important risk factor for severe outcomes.
Why it matters
This rapid review found low or moderate certainty evidence that dementia was associated with a large increase in hospitalisation from COVID-19. It concerns COVID-19 severity and vaccine prioritisation, not treating, curing or preventing Alzheimer's disease.
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Cognitive impairment is a common non-motor symptom in Parkinson's Disease (PD) and an important source of patient disability and caregiver burden.
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Most prevalent neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, Parkinson's disease and multiple sclerosis are heterogeneous in their clinical profiles and underlying pathophysiology, although they typically share the presence of cognitive impairment that worsens significantly during the course of the disease.
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This study highlights the need for nursing homes to employ specialist nurses who have been trained in the appropriate knowledge and skills to deal with the challenges of end-of-life care for people with advanced dementia and pain.
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Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe.
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Dementia and cancer occur commonly in older adults.
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Annual Wellness Visit utilization was associated with an increased probability of new dementia diagnosis with effects varying by racial group (categorized as white, black, Hispanic/Latino, or Asian based on Social Security Administration data).
Why it matters
This study found that attending a Medicare Annual Wellness Visit was associated with an increased probability of receiving a new dementia diagnosis, with effects varying by racial group. It is about diagnosis rates, not about treating, curing, or preventing Alzheimer's disease.
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43/100
This prospective study found that high consumption of Western diet components attenuates benefits of the MedDiet on cognition.
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There are palliative care validated instruments to assess the sedation effect but this review shows the need for a more standardized approach when assessing it.
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In October 2019, a Swiss panel of experts met for the Dementia Summit in Brunnen, Switzerland, to discuss the latest scientific findings on basic and clinical research, as well as practical and political approaches to the challenges of dementia disorders in Switzerland.
Why it matters
This conference report describes experimental approaches including transgenic mouse models for studying pathophysiological changes and fluid biomarker changes in dementia. It notes that more than one third of identified dementia risk factors can be modified.
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The sense of food insecurity in a group of elderly people may be determined by the perception of distance to food outlets.
Why it matters
This survey of 762 Polish elderly people found that 20.5% felt food insecure because they lived too far from grocery shops, and some reduced consumption of fish, fruits, vegetables, and beef as a result. It has no relevance to treating, curing, or preventing Alzheimer's disease.
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We found no papers that informed the 'cultural aspects of care' domain.
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The number of elderly is growing rapidly, including those that struggle with cognitive decline and, consequently, activities of daily living.
Why it matters
This review describes ways immersive virtual reality might be used to train cognition and detect cognitive changes in older people. However, the available studies are small scale and have not been replicated, so it is too early to say whether this helps treat or prevent dementia.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial
- Cognitive Rehabilitation in Alzheimer's Disease: A Controlled Intervention Trial
- Disagreement between self- and informant-reported memory complaints and progression of mild cognitive impairment to dementia
- Long‐term outcomes after rehabilitation in Medicare Advantage and fee‐for‐service beneficiaries
- Antipsychotics for delirium
- The MoCA: well-suited screen for cognitive impairment in Parkinson disease
- Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort Study
- Intervention Development for Tailored Education for Aging and Cognitive Health (TEACH) for Dementia Prevention in Midlife Adults: Protocol for a Randomized Controlled Trial
- Statin discontinuation in nursing home residents with advanced dementia
- Use it or lose it? Wii brain exercise practice and reading for domain knowledge