Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Download bibliography of all 8,032 studies, highest score first: BibTeX (.bib) · RIS (.ris)
Highest usefulness score first. Studies without a score come last.
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The ViT approach predicted dementia with 76.5% balanced accuracy, outperforming human-scored features (74.3%) and existing deep learning models (MiniVGG = 73.3%, MobileNetV2 = 72.3%, relevance factor variational autoencoder = 69.1%) on the TDRA dataset.
Why it matters
A vision transformer model predicted dementia from clock drawing test images with 76.5% balanced accuracy, slightly outperforming human scoring and other deep learning models. This automated approach could enable scalable remote screening, but it is a diagnostic tool and does not treat or prevent dementia.
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Of the 127 participants, one-third died during their stay.
Why it matters
Among 127 patients with dementia and very severe challenging behavior admitted to specialized units, one-third died during their stay, with the most aggressive patients having a ninefold increased mortality risk. It underlines the need for suitable terminal palliative care in this patient group.
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Artificial intelligence (AI) is revolutionizing the field of medical imaging, offering unprecedented capabilities in data analysis, image interpretation, and decision support.
Why it matters
This review describes how AI is being applied to transcranial Doppler and ultrasound imaging, such as detecting vasospasm and emboli, but notes that data standardization, algorithm interpretability, and clinical integration remain unresolved. It reports no treatment, cure, or prevention of Alzheimer's disease.
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Significant correlations emerged between higher MEDAS scores and BMI (r = −0.53, p < 0.01), FM% (r = −0.49, p < 0.01), VAT (r = −0.63, p < 0.01), and cIMT (r = −0.88, p < 0.01).
Why it matters
This study examined adherence to the Mediterranean diet and cardiovascular risk markers such as BMI, visceral fat, blood pressure and carotid intima-media thickness. It reports benefits for vascular health and cardiovascular disease prevention, but it does not address Alzheimer's disease.
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Ethnoracial identity was significantly associated with the likelihood of ACP engagement.
Why it matters
Non-Hispanic Black and Hispanic people with ADRD engaged in fewer advance care planning activities than non-Hispanic White counterparts. This is about care planning disparities, not about treating, curing, or preventing Alzheimer's disease.
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45/100
Representations of White-racialized older adults were 5-fold higher than those of other races in both years.
Why it matters
This study found that AI text-to-image generators kept producing ageist images over two years, mostly of White-racialized older adults, with no improvement in emotional representation despite neutral prompts. It is about bias in generated images and has no bearing on treating, curing or preventing Alzheimer's disease.
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We describe the complex care needs faced by families in dementia care and specialized multidisciplinary palliative care delivered through home visits as a feasible way to support advancing stages of dementia.
Why it matters
This preliminary longitudinal study of 47 participants found that multidisciplinary home-based palliative care significantly reduced palliative care concerns, while caregiver burden showed a slight increase at three months. The authors call for further longitudinal studies with robust methodology.
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45/100
NPs reported that the quality of dementia care in their practices is poorer than the overall care provided.
Why it matters
This cross-sectional survey found that nurse practitioners rated dementia care in their primary care practices as poorer than overall care, with significant gaps in structural capabilities and over a third reporting burnout. It describes problems in care delivery rather than testing any treatment, cure or prevention for Alzheimer's disease.
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Estimates suggest a high social burden from ADRD, with annual costs increasing from 0.9% to 3.8% of gross domestic product between 2019 and 2050.
Why it matters
This review highlights the challenges of rapid aging in Korea, with dementia costs projected to rise from 0.9% to 3.8% of gross domestic product between 2019 and 2050, and notes that pilot programs for integrated community care and hospice palliative care show promise. It calls for rigorous analysis of programs to address uneven quality, but reports no results on treating, curing or preventing Alzheimer's disease.
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The ResQ-Care-Dem scales' internal consistencies ranged between 0.65 and 0.81.
Why it matters
This cross-sectional study assessed a questionnaire for measuring burden and resilience in caregivers of people with dementia, finding partial confirmation of reliability and structural validity. It is a measurement tool study, not a test of any treatment, cure or prevention for dementia.
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This paper reports on a Conference organized by the Washington University School of Medicine's (WUSM) Knight Alzheimer Disease Research Center (Knight ADRC), entitled "Enhancing Participation by Minoritized Groups in Alzheimer Disease and Related Dementia (ADRD) Research."
Why it matters
This conference report describes strategies to enhance participation of historically minoritized groups in Alzheimer's disease and related dementias research. It addresses research inclusion, not treating, curing, or preventing the disease.
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Of the association between apathy and dementia (HR 1.49 [95% CI 0.99-2.41]), 27% was mediated by physical inactivity, BMI and diabetes combined.
Why it matters
This analysis suggests that part of the link between apathy and dementia runs through physical inactivity, BMI and diabetes, which are potentially modifiable. It does not show that treating apathy or changing these factors prevents dementia, and the overall apathy-dementia association was not statistically significant.
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The intervention engaged 69 (63.8%) of 108 clinicians across the 7 clinics.
Why it matters
This study describes implementing a digital cognitive assessment tool in primary care, with screening completed in 10.8% of eligible visits and four of seven clinics fully adopting it. It is about detecting cognitive impairment in primary care, not about treating, curing or preventing Alzheimer's disease.
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Except for the visual-spatial memory test, nonlinear approaches provided a better fit than linear methods to model the associations of sedentary time with other cognitive outcomes.
Why it matters
In this UK Biobank analysis, higher sedentary time was associated with slightly better cognitive performance up to a threshold of about 9.7 to 12.3 hours per day, above which the association weakened or turned negative. These are small observational associations and do not show that sedentary behaviour prevents or causes cognitive decline.
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DRRLS score of 83.61 ± 16.13, multiple linear regression showed that the patient's monthly individual income, the presence of chronic disease, health beliefs, and social support were independent influences on their dementia risk reduction lifestyle.
Why it matters
This cross-sectional study found that factors such as income, chronic disease, health beliefs, social support, and caregiver characteristics were linked to dementia risk reduction lifestyle in people with mild cognitive impairment. Because it is cross-sectional, it cannot show whether changing these factors prevents or delays dementia.
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Study-specific algorithms yielded comparable dementia prevalence estimates: 10.8 % in NHATS and 11.1 % in HRS-HCAP.
Why it matters
This study found that co-calibrated cognitive scores from two large studies yielded comparable dementia prevalence estimates and had acceptable reliability. Co-calibrated scores provide a valid and feasible approach for comparative research on dementia in the US.
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We recruited 596 men and 273 women prisoners.
Why it matters
This cross-sectional study found that 7.0% of older prisoners in England and Wales screened positive for dementia, with many undiagnosed. The findings highlight a need for better recognition and services, but do not provide a treatment, cure, or prevention.
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The studied cohort comprised 4601 patients, mean age of 83.93 years and 56.26% were women.
Why it matters
In this Colombian cohort, delirium on admission was common and was linked to malnutrition, dementia, functional impairment and swallowing difficulty, while social factors showed no significant link. It identifies clinical risk factors but reports no treatment or cure for Alzheimer's disease.
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This paper proposes a novel LLM-aided feature engineering approach that enhances interpretability by extracting clinically relevant features from the Oxford Textbook of Medicine.
Why it matters
This paper proposes an LLM-aided feature engineering approach to make machine learning predictions of dementia types more explainable, achieving accuracy of 0.72. It is about improving the interpretability of diagnostic models, not about treating, curing, or preventing Alzheimer's disease.
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We enrolled 32 patients, 32 caregivers, and 25 clinicians.
Why it matters
In this study of 32 patients, 32 caregivers and 25 clinicians, transitions in medication management responsibilities typically occurred after reduced patient capacity, and clinicians did not routinely give caregivers an overview of medications even though caregivers wanted one. It identifies opportunities for early planning and supplemental counseling, but does not test any treatment, cure or prevention for dementia.
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Participants were distributed across various regions of Australia: seven interviews from inner regional Australia, five interviews from outer regional Australia, and twenty-one interviews from metropolitan areas.
Why it matters
This qualitative study in Australia found disparities between rural and metropolitan areas in geography, travel costs, service availability, acceptability, and awareness of local services. It identifies health inequities that need targeted action, rather than testing a treatment.
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The global population is aging, and as a consequence, the prevalence of dementia is increasing rapidly.
Why it matters
The global burden of dementia increased from 1990 to 2021, with incidence, prevalence, and disability-adjusted life years all rising, and the burden is projected to continue increasing until 2040. The study highlights the need for prevention and control measures, especially as the population ages.
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High Resolution Image Download MS PowerPoint Slide Fine particulate matter (PM 2.5 ) is linked to dementia risk, but ultrafine particles (UFPs, <100 nm) may be even more toxic due to their distinct physicochemical properties.
Why it matters
Among about 21 million Medicare participants, each interquartile range increase in ultrafine particle exposure was linked to slightly higher risks of Alzheimer's disease and related dementias. This identifies a possible environmental risk factor and calls for public health interventions, but does not test any treatment, cure, or prevention.
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Exceeding the ambitions of the Sendai Framework for Disaster Risk Reduction 2015-2030, to switch the focus of DRR (Disaster Risk Reduction) solutions from top-down to people-centred approaches, requires a better understanding of the complexity and dynamics of citizen and stakeholder engagement in DRR processes.
Why it matters
This paper is about stakeholder engagement in disaster risk reduction and contains no information on Alzheimer's disease. It reports no findings relevant to treating, curing or preventing dementia.
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Participating ICU in both surveys (2016: n = 559, 2024: n = 447) had similar basic characteristics and enabled comparison.
Why it matters
This comparison of two surveys in 2016 and 2024 found a slight cultural shift in delirium management in German-speaking ICUs, with increased use of validated assessment tools and prevention programs. However, dementia screening decreased, and lack of time and staff remained the top barrier.
From across this topic
10 of the 7,981 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Increased fMRI responses during encoding in mild cognitive impairment
- Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study
- Longitudinal MRI and cognitive change in healthy elderly
- Impact of cerebral small vessel disease on cognitive outcomes in early age at onset MCI and dementia: Findings from the DIASPORA study
- Hospitalization risk with and without dementia by region and race in the United States
- Default mode network connectivity in stable vs progressive mild cognitive impairment
- The hippocampus and depression
- Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study
- An Internet-Based Intervention Augmented With a Diet and Physical Activity Consultation to Decrease the Risk of Dementia in At-Risk Adults in a Primary Care Setting: Pragmatic Randomized Controlled Trial
- Social Isolation as a Risk Factor for Dementia: Insights from Animal Model Studies