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Hospitalization risk with and without dementia by region and race in the United States
Lauren Mock, Daniel Mork, Michelle Audirac, Danielle Braun, Antonella Zanobetti, Scott Delaney. American Journal of Epidemiology, 2026-04-21
Topic: Risk, prevention and care in population studies
Plain-language summary
Understanding regional and racial variation in the risk of hospitalization with Alzheimer's disease and related dementias (ADRD)-and how it differs from other conditions-is required to inform effective practice and policy. However, no prior studies have simultaneously estimated county-level regional and race-specific variation in hospitalization risk. We assessed hospitalizations with and without ADRD diagnoses among Black and White Medicare Fee-for-Service beneficiaries from 2000 to 2018 and used Bayesian shared component models to estimate geographic variation in hospitalizations jointly for both racial groups. We decomposed hospitalization risk across 3037 counties into (1) risk shared by all beneficiaries and (2) risk specific to either Black or White beneficiaries. We analyzed 143 891 769 hospitalizations (13.2% with ADRD). For hospitalization with ADRD, shared risk was elevated in southern and eastern states; Black-specific risk was elevated in the Midwest, Florida, and California; and White-specific risk was elevated in Appalachia. Black relative risk was significantly higher than White relative risk in 90.2% (2740/3037) of counties for hospitalization with ADRD and 44.7% (1359/3037) of counties for hospitalization without ADRD. These findings underscore the importance of considering regional differences in race-specific risk when assessing hospitalization disparities.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Mock, L., Mork, D., Audirac, M., Braun, D., Zanobetti, A., & Delaney, S. (2026). Hospitalization risk with and without dementia by region and race in the United States. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwag087
Vancouver
Mock L, Mork D, Audirac M, Braun D, Zanobetti A, Delaney S. Hospitalization risk with and without dementia by region and race in the United States. American Journal of Epidemiology. 2026. doi:10.1093/aje/kwag087. PMID: 42017264.
BibTeX
@article{mock2026-42017264,
author = {Mock, Lauren and Mork, Daniel and Audirac, Michelle and Braun, Danielle and Zanobetti, Antonella and Delaney, Scott},
title = {{Hospitalization risk with and without dementia by region and race in the United States}},
journal = {American Journal of Epidemiology},
year = {2026},
doi = {10.1093/aje/kwag087},
pmid = {42017264},
url = {https://doi.org/10.1093/aje/kwag087}
}
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Key findings
- Black relative risk was significantly higher than White relative risk in 90.2% (2740/3037) of counties for hospitalization with ADRD and 44.7% (1359/3037) of counties for hospitalization without ADRD.
- These findings underscore the importance of considering regional differences in race-specific risk when assessing hospitalization disparities.
Why it matters
Among Black and White Medicare beneficiaries, hospitalization risk with Alzheimer's disease and related dementias varied by region and race. Black relative risk was significantly higher than White relative risk in 90.2% of counties for hospitalization with dementia.
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Study details
- Participants143
- Effect size13.2%; 90.2%; 44.7%
- Evidence strengthLow
How this study scored 40/100
Published in a peer-reviewed journal. Scored zero for study design and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (American Journal of Epidemiology) |
| Journal's citation record | 3 / 4 | American Journal of Epidemiology: journal h-index 416 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 2 / 4 | 143 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Scott Delaney: h-index 18 (OpenAlex, whole career) |
| Institution's track record | 3 / 3 | Harvard University: institution h-index 3,235 (OpenAlex) |
| Multicenter collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42017264) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 40 / 100 | — |
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