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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,201–25,225 of 27,380 studies, newest first · page 1009 of 1096.

April 2001 11

  1. 2001-04-01

    Pathways to neuronal injury and apoptosis in HIV-associated dementia

    ✓ Peer-reviewed Inflammation and the immune system Nature

    Key finding: The mechanism remains poorly understood, but discovery in brain of HIV-1-binding sites (chemokine receptors) provides new insights. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2001-04-01

    DNA replication precedes neuronal cell death in Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Despite progress in uncovering many of the factors that contribute to the etiology of the disease, the cause of the nerve cell death remains unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2001-04-01

    Mild cognitive impairment and Alzheimer disease: regional diffusivity of water

    ✓ Peer-reviewed Mild cognitive impairment Radiology

    Key finding: Hippocampal ADC was significantly different between control subjects and MCI patients, many of whom likely have preclinical Alzheimer disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2001-04-01

    A reevaluation of the duration of survival after the onset of dementia

    ✓ Peer-reviewed Lewy body dementia The New England journal of medicine

    Key finding: Median survival after the onset of dementia is much shorter than has previously been estimated.

    Full summary, score breakdown and related studies → Original source

  5. 2001-04-01

    Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Archives of pathology & laboratory medicine

    Key finding: We propose the following sequence of events in the development of neuropathologic changes of Alzheimer disease in Down syndrome: (1) intracellular accumulation of Abeta in neurons and astrocytes, (2) deposition of extracellular Abeta and formation of diffuse plaques, and (3) development of neuritic plaques and neurofibrillary tangles with activation of microglial cells.

    Full summary, score breakdown and related studies → Original source

  6. 2001-04-01

    Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients

    ✓ Peer-reviewed Risk factors Archives of internal medicine

    Key finding: Exposure to ACH medications is independently and specifically associated with a subsequent increase in delirium symptom severity in elderly medical inpatients with diagnosed delirium. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2001-04-01

    Dementia family caregiver training: affecting beliefs about caregiving and caregiver outcomes

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: This study tested role-training intervention as a way to help family caregivers appreciate and assume a more clinical belief set about caregiving and thereby ameliorate the adverse outcomes associated with caregiving. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2001-04-01

    Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration

    ✓ Peer-reviewed Caregiving Archives of general psychiatry

    Key finding: Patients with AD and patients with FTD show different disturbances in their rhythms of activity and temperature compared with each other and with normal elderly patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2001-04-01

    A review of MRI findings in schizophrenia

    ✓ Peer-reviewed Brain scans and imaging Schizophrenia research

    Key finding: The results of subsequent neuropathological studies were disappointing because of conflicting findings. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2001-04-01

    Primary progressive aphasia

    ✓ Peer-reviewed Getting a diagnosis Annals of neurology

    Key finding: An informed approach to this syndrome will increase the effectiveness with which clinicians can address the unique challenges associated with the diagnosis and care of PPA.

    Full summary, score breakdown and related studies → Original source

  11. 2001-04-01

    Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: In this study, we examined which apoE fragments are most strongly associated with amyloid deposits and whether apoE receptor binding domains were present. +4 more findings

    Full summary, score breakdown and related studies → Original source

March 2001 14

  1. 2001-03-15

    Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: High level production of the pathogenic Abeta42 form of Abeta peptide was associated with an early impairment in TgCRND8 mice in acquisition and learning reversal in the reference memory version of the Morris water maze, present by 3 months of age.

    Full summary, score breakdown and related studies → Original source

  2. 2001-03-13

    Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

    ✓ Peer-reviewed Genetics Proceedings of the National Academy of Sciences

    Key finding: The epsilon4 heterozygotes had significant CMRgl declines in the vicinity of temporal, posterior cingulate, and prefrontal cortex, basal forebrain, parahippocampal gyrus, and thalamus, and these declines were significantly greater than those in the epsilon4 noncarriers.

    Full summary, score breakdown and related studies → Original source

  3. 2001-03-06

    Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

    ✓ Peer-reviewed Risk factors Proceedings of the National Academy of Sciences

    Key finding: The increase in time devoted to intellectual activities from early adulthood (20-39) to middle adulthood (40-60) was associated with a significant decrease in the probability of membership in the case group. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2001-03-01

    Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease

    ✓ Peer-reviewed Treatments Archives of neurology

    Key finding: Donepezil is an effective and safe drug for the long-term symptomatic treatment of mild to moderately severe AD for up to 144 weeks (2.8 years), and sustained treatment may confer some advantages. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2001-03-01

    Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD

    ✓ Peer-reviewed Vascular contributions Neurology

    Key finding: Temporoparietal hypoperfusion on SPECT is common to both AD and DLB. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2001-03-01

    Longitudinal study of brain morphology in first episode schizophrenia

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Although numerous studies of the longitudinal course of schizophrenia have demonstrated the clinical deterioration that occurs predominantly in the early stages of the illness, the pathophysiology of this clinical phenomenon has not been established. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2001-03-01

    Frailty in Older Adults: Evidence for a Phenotype

    ✓ Peer-reviewed How common it is The Journals of Gerontology Series A

    This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition.

    Full summary, score breakdown and related studies → Original source

  8. 2001-03-01

    Amyloid precursor protein in platelets of patients with Alzheimer disease: effect of acetylcholinesterase inhibitor treatment

    ✓ Peer-reviewed Risk genes beyond APOE Archives of neurology

    Key finding: All patients taking donepezil completed the 30 days of treatment without adverse effects. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2001-03-01

    Hippocampal volume discriminates between normal cognition; questionable and mild dementia in the elderly

    ✓ Peer-reviewed Cognitive tests and assessment Neurobiology of aging

    Key finding: According to Clinical dementia rating (CDR), 17 subjects had normal cognition (CDR 0), 12 had questionable (CDR 0.5) and 10 mild dementia (CDR 1). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2001-03-01

    Caregivers' judgments of the functional abilities of the Alzheimer's disease patient: a comparison of proxy reports and objective measures

    ✓ Peer-reviewed Cognitive tests and assessment The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Although ratings of functional disability by family or other proxy informants are widely used by clinicians, there have been concerns and empirical evidence that potential reporter biases may result in either overestimation or underestimation of specific functional deficits. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2001-03-01

    Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

    ✓ Peer-reviewed Risk genes beyond APOE Brain research

    Key finding: Tg2576 mice studied at postnatal ages of 13, 16 and 19 months demonstrated an age-related accumulation of both senile and diffuse beta-amyloid plaques in neocortex and hippocampus. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2001-03-01

    Magnetic resonance spectroscopy in AD

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: Less robust evidence using phosphorous MRS has shown significant phosphocreatine decline and increments in the cell membrane phosphomonoesters in the early, and possibly asymptomatic, stages of the disease.

    Full summary, score breakdown and related studies → Original source

  13. 2001-03-01

    Mild cognitive impairment represents early-stage Alzheimer disease

    ✓ Peer-reviewed Mild cognitive impairment Archives of neurology

    Key finding: Individuals currently characterized as having MCI progress steadily to greater stages of dementia severity at rates dependent on the level of cognitive impairment at entry and they almost always have the neuropathologic features of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2001-03-01

    Distinct behavioural profiles in frontotemporal dementia and semantic dementia

    ✓ Peer-reviewed Lewy body dementia Journal of neurology, neurosurgery, and psychiatry

    Key finding: The findings confirm predictions regarding behavioural differences in frontotemporal and semantic dementia and point to differential roles of the frontal and temporal lobes in affect, social functioning, eating, and compulsive behaviour. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →