Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 24,826–24,850 of 27,380 studies, newest first · page 994 of 1096.
June 2002 13
-
2002-06-01
Association between high-density lipoprotein and cognitive impairment in the oldest old
50/100 ✓ Peer-reviewed Cognitive tests and assessment Annals of neurology
Key finding: At the same time, cardiovascular disease and stroke are important risk factors for dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Developmental neurobiology of childhood stress and trauma
45/100 ✓ Peer-reviewed Lewy body dementia The Psychiatric clinics of North America
Key finding: Severe early stress and maltreatment produces a cascade of events that have the potential to alter brain development. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations
45/100 ✓ Peer-reviewed Lewy body dementia Biological psychiatry
Key finding: Previous demonstrations of hypofrontality in schizophrenia may reflect particular task requirements. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters
47/100 ✓ Peer-reviewed Lewy body dementia Journal of neuroscience research
Key finding: Accumulation of alpha-synuclein has been associated with neurodegenerative disorders, such as Lewy body disease and multiple system atrophy. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Elevated expression of beta-site amyloid precursor protein cleaving enzyme 2 in brains of patients with Down syndrome
38/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters
Key finding: The gene encoding the beta-site amyloid precursor protein cleaving enzyme 2 (BACE2) has been determined to be located on the long arm of chromosome 21 at 21q22.3. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress
42/100 ✓ Peer-reviewed Down syndrome and Alzheimer's FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Key finding: Although DSCR1 (Adapt78) has been associated with successful adaptation to oxidative stress and calcium stress and with devastating diseases such as Alzheimer's and Down syndrome, no rationale for these apparently contradictory findings has been tested. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Incidence and prediction of falls in Parkinson's disease: a prospective multidisciplinary study
54/100 ✓ Peer-reviewed How common it is Journal of neurology, neurosurgery, and psychiatry
Key finding: Falls are a common problem in PD and some of the major risk factors are potentially modifiable. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Dietary intake of antioxidants and risk of Alzheimer disease
70/100 ✓ Peer-reviewed How common it is JAMA
Key finding: High dietary intake of vitamin C and vitamin E may lower the risk of Alzheimer disease. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
How effective are interventions with caregivers? An updated meta-analysis
68/100 ✓ Peer-reviewed Caregiving The Gerontologist
Key finding: The combined interventions produced a significant improvement of 0.14 to 0.41 standard deviation units, on average, for caregiver burden, depression, subjective well-being, perceived caregiver satisfaction, ability/knowledge, and care receiver symptoms.
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Five-year outcome of normal pressure hydrocephalus with or without a shunt: predictive value of the clinical signs, neuropsychological evaluation and infusion test
40/100 ✓ Peer-reviewed Brain scans and imaging Acta neurochirurgica
Key finding: 25 of the patients needed a shunt operation. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project
58/100 ✓ Peer-reviewed Getting a diagnosis American journal of epidemiology
Key finding: Recent findings suggest that a rich social network may decrease the risk of developing dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2002-06-01
The prevalence of frontotemporal dementia
60/100 ✓ Peer-reviewed Getting a diagnosis Neurology
Key finding:
Full summary, score breakdown and related studies → Original source
-
2002-06-01
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
53/100 ✓ Peer-reviewed Genetics JAMA
Key finding: This study suggests that vitamin E from food, but not other antioxidants, may be associated with a reduced risk of AD. +3 more findings
Full summary, score breakdown and related studies → Original source
May 2002 12
-
2002-05-21
Quantifying heterogeneity in a meta‐analysis
49/100 ✓ Peer-reviewed How common it is Statistics in Medicine
The extent of heterogeneity in a meta-analysis partly determines the difficulty in drawing overall conclusions.
Full summary, score breakdown and related studies → Original source
-
2002-05 month only
Nefiracetam. Daiichi Seiyaku
38/100 ✓ Peer-reviewed Clinical trials Current opinion in investigational drugs (London, England : 2000)
Key finding: By September 1999, nefiracetam was In phase II trials in the US for the treatment of mental symptoms associated with sequelae of stroke and Alzheimer's type dementia.
Full summary, score breakdown and related studies → Original source
-
2002-05 month only
Pharmacologic treatments of dementia
38/100 ✓ Peer-reviewed Treatments The Medical clinics of North America
Key finding: This standard is based on the results of large-scale, double-blind, placebo-controlled trials. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome
36/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Neuroscience letters
Key finding: We used Western blotting to determine protein levels of drebrin and F-actin in frontal, temporal cortex and cerebellum from patients with DS and AD as compared to controls. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Use of anticholinergic medications by older adults with dementia
48/100 ✓ Peer-reviewed Digital health tools Journal of the American Geriatrics Society
Key finding: Community-based, commercially insured, older adults with probable dementia are more likely to take anticholinergics than matched controls. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-05-01
The cost of behavioral and psychological symptoms of dementia (BPSD) in community dwelling Alzheimer's disease patients
36/100 ✓ Peer-reviewed Health systems and care delivery International journal of geriatric psychiatry
Key finding: Approximately 30% (4115 dollars) of the total annual cost of AD (14420 dollars) is invested in the direct management of BPSD. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
36/100 ✓ Peer-reviewed Disease mechanisms Human molecular genetics
Key finding: Protein conformational disorders (PCDs), such as Alzheimer's disease, Huntington's disease (HD), Parkinson's disease and oculopharyngeal muscular dystrophy, are associated with proteins that misfold and aggregate. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Air pollution and brain damage
36/100 ✓ Peer-reviewed Risk factors Toxicologic pathology
Key finding: Exposure to complex mixtures of air pollutants produces inflammation in the upper and lower respiratory tract.
Full summary, score breakdown and related studies → Original source
-
2002-05-01
A path model of chronic stress, the metabolic syndrome, and coronary heart disease
43/100 ✓ Peer-reviewed Risk factors Psychosomatic medicine
Key finding: In older men, pathways occurred from chronic stress to distress to the metabolic syndrome, which in turn predicted CHD.
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies
53/100 ✓ Peer-reviewed Brain scans and imaging The American journal of psychiatry
Key finding: Power analyses for voxels showing maximal decline over the 1-year period in regional cerebral glucose metabolism (mg/100 g per minute) were computed to estimate the sample sizes needed to detect a significant treatment response in a 1-year, double-blind, placebo-controlled treatment study. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
40/100 ✓ Peer-reviewed Tau biomarkers Nature neuroscience
Key finding: We have previously shown that chronic treatment with the monoclonal antibody m266, which is specific for amyloid beta-peptide (Abeta), increases plasma concentrations of Abeta and reduces Abeta burden in the PDAPP transgenic mouse model of Alzheimer's disease (AD). +1 more finding
Full summary, score breakdown and related studies → Original source
-
2002-05-01
Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy
66/100 ✓ Peer-reviewed Hippocampus size on brain scans Annals of neurology
Key finding: This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years. +1 more finding
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →