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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,701–23,725 of 27,380 studies, newest first · page 949 of 1096.

April 2005 25

  1. 2005-04-01

    Neuroprotectin D1 (NPD1): a DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress

    ✓ Peer-reviewed Brain scans and imaging Brain pathology (Zurich, Switzerland)

    Key finding: A time-dependent release of endogenous free DHA followed by NPD1 formation occurs, suggesting that a phospholipase A2 releases the mediator's precursor. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2005-04-01

    The human pineal gland and melatonin in aging and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Journal of pineal research

    Key finding: Circadian disorders, such as sleep-wake cycle disturbances, are associated with aging, and even more pronounced in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2005-04-01

    Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Recent epidemiological studies, however, suggest that lifestyle changes may slow the onset/progression of AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2005-04-01

    Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Journal of neuroscience research

    Key finding: Histochemical analysis revealed citrullinated proteins throughout the hippocampus, especially in the dentate gyrus and stratum radiatum of CA1 and CA2 areas. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2005-04-01

    Subclinical brain magnetic resonance imaging abnormalities predict physical functional decline in high-functioning older adults

    ✓ Peer-reviewed Vascular contributions Journal of the American Geriatrics Society

    Key finding: Subclinical structural brain abnormalities in high-functioning older adults can increase the risk of developing physical disabilities and declining in motor performance.

    Full summary, score breakdown and related studies → Original source

  6. 2005-04-01

    Malnutrition and associated factors among aged residents in all nursing homes in Helsinki

    ✓ Peer-reviewed Vascular contributions European journal of clinical nutrition

    Key finding: Although internal factors explain most about the poor nutritional status of aged residents in nursing homes, the factors related to nutritional care need further investigation to clarify their role in maintaining the nutritional status of aged residents. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2005-04-01

    Reduced hippocampal volume in unmedicated, remitted patients with major depression versus control subjects

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Recurrent depression is associated with smaller hippocampal volume which is most prominent in the posterior hippocampus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2005-04-01

    Preclinical detection of Alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: Inward variation of the lateral zone and left hippocampal volume significantly predicted conversion to CDR 0.5 in separate Cox proportional hazards models. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2005-04-01

    Predicting death in the nursing home: development and validation of the 6-month Minimum Data Set mortality risk index

    ✓ Peer-reviewed End-of-life care The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: A reasonably accurate, validated model has been produced, with clinical application through a scored point system, to assist clinicians, residents, and family members in defining good goals of care around end-of-life care.

    Full summary, score breakdown and related studies → Original source

  10. 2005-04-01

    Feasibility and reliability of four pain self-assessment scales and correlation with an observational rating scale in hospitalized elderly demented patients

    ✓ Peer-reviewed Clinical safety The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Self-assessment pain scales can be used reliably in the vast majority of older hospitalized patients with mild to moderate dementia and in nearly half of those with severe dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2005-04-01

    Falls and injuries resulting from falls among patients with Parkinson's disease and other parkinsonian syndromes

    ✓ Peer-reviewed Clinical safety Movement disorders : official journal of the Movement Disorder Society

    Key finding: Explanatory variables included sex, age, age at diagnosis, disease duration, atypical parkinsonism, and dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2005-04-01

    Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Whereas endogenous tau was not detected in astrocytes of control mice, in GFAP/tau Tg mice there was robust astrocytic tau expression that was associated with a redistribution of the GFAP network.

    Full summary, score breakdown and related studies → Original source

  13. 2005-04-01

    Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: We have employed a proteomic approach, microcapillary liquid chromatography mass spectrometry of proteins labeled with isotope-coded affinity tags (ICAT), to quantify relative changes in the proteome of human cerebrospinal fluid (CSF) obtained from the lumbar cistern. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2005-04-01

    Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of disease

    Key finding: Here, we examine cognition in 6- and 18-month old transgenic mice expressing APPswe and PS1dE9, alone and in combination. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2005-04-01

    Evidence of increased oxidative damage in subjects with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: Oxidative damage occurs in the brain of subjects with mild cognitive impairment, suggesting that oxidative damage may be one of the earliest events in the onset and progression of Alzheimer disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2005-04-01

    Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study

    ✓ Peer-reviewed Lewy body dementia American journal of epidemiology

    Key finding: After multivariate adjustment, participants in the highest quartile of physical energy expenditure had a relative risk of dementia of 0.85 (95% confidence interval: 0.61, 1.19) compared with those in the lowest quartile, and participants engaging in >or=4 activities had a relative risk of dementia of 0.51 (95% confidence interval: 0.33, 0.79) compared with those engaging in 0-1 activity.

    Full summary, score breakdown and related studies → Original source

  17. 2005-04-01

    The natural history of temporal variant frontotemporal dementia

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: The temporal variant of frontotemporal dementia follows a characteristic cognitive and behavioral progression that suggests early spread from one anterior temporal lobe to the other. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2005-04-01

    Dementia caregiving: the experiences of Hispanic/Latino caregivers

    ✓ Peer-reviewed Disparities Journal of transcultural nursing : official journal of the Transcultural Nursing Society

    Key finding: This qualitative, descriptive, cross-sectional study used Leininger's ethnonursing approach. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2005-04-01

    The pathology of the substantia nigra in Alzheimer disease with extrapyramidal signs

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: In some cases, limited nigral pathology suggests extranigral factors in the clinical symptoms of EPS.

    Full summary, score breakdown and related studies → Original source

  20. 2005-04-01

    Cognitive status correlates with neuropathologic stage in Parkinson disease

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: It was possible to assign all patients to one of the PD stages. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2005-04-01

    Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD

    ✓ Peer-reviewed Getting a diagnosis European journal of nuclear medicine and molecular imaging

    Key finding: MRI findings provide strong evidence that in mild cognitive impairments (MCI), AD-related volume losses can be reproducibly detected in the hippocampus, the entorhinal cortex (EC) and, to a lesser extent, the parahippocampal gyrus; they also indicate that lateral temporal lobe changes are becoming increasingly useful in predicting the transition to dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2005-04-01

    The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment

    ✓ Peer-reviewed Getting a diagnosis Journal of the American Geriatrics Society

    Key finding: MCI as an entity is evolving and somewhat controversial.

    Full summary, score breakdown and related studies → Original source

  23. 2005-04-01

    Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial

    ✓ Peer-reviewed Prevention and risk The American journal of psychiatry

    Key finding: Raloxifene at a dose of 120 mg/day, but not 60 mg/day, resulted in reduced risk of cognitive impairment in postmenopausal women. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2005-04-01

    The effect of integrated emotion-oriented care versus usual care on elderly persons with dementia in the nursing home and on nursing assistants: a randomized clinical trial

    ✓ Peer-reviewed Treatments International journal of geriatric psychiatry

    Key finding: Emotion-oriented care is more effective with regard to the emotional adaptation in nursing homes of persons with a mild to moderate dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2005-04-01

    Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease?

    ✓ Peer-reviewed Treatments The American journal of psychiatry

    Key finding: Donepezil treatment slows the progression of hippocampal atrophy, suggesting a neuroprotective effect of donepezil in Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →