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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,151–24,175 of 27,380 studies, newest first · page 967 of 1096.

April 2004 19

  1. 2004-04-01

    Cognitive impairment and functional outcome after stroke associated with small vessel disease

    ✓ Peer-reviewed Vascular contributions Journal of neurology, neurosurgery, and psychiatry

    Key finding: Half of the patients with SSVD complained of varying severity of cognitive problems 3 months after stroke. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2004-04-01

    Depression and vascular disease: what is the relationship?

    ✓ Peer-reviewed Vascular contributions Journal of affective disorders

    Key finding: We investigated the nature of the relationship between depression and vascular diseases by reviewing epidemiological, clinical, neuroimaging and neuropathology studies which have reported on the relationship of depression to coronary artery disease, stroke disease, alterations in blood pressure, vascular dementia, diabetes mellitus and cholesterol levels and by reviewing potential mechanisms by which depression could be associated with vascular diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2004-04-01

    Alcohol intake and risk of dementia

    ✓ Peer-reviewed Vascular contributions Journal of the American Geriatrics Society

    Key finding: Consumption of up to three servings of wine daily is associated with a lower risk of AD in elderly individuals without the APOE epsilon-4 allele. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2004-04-01

    Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up

    ✓ Peer-reviewed Hippocampus size on brain scans The Journal of clinical psychiatry

    Key finding: These results do not support the hypothesis that hippocampal volumes diminish during the 1-year follow-up period. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2004-04-01

    Regional specificity of hippocampal volume reductions in first-episode schizophrenia

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: Some studies suggest anterior hippocampal regions are more susceptible and associated with frontal lobe dysfunctions, while others implicate posterior regions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2004-04-01

    Lower hippocampal volume in patients suffering from depression: a meta-analysis

    ✓ Peer-reviewed Hippocampus size on brain scans The American journal of psychiatry

    Key finding: Although the effect of major depressive disorder on amygdala volume remains to be conclusively established, inclusion of the amygdala with the hippocampus appears to have decreased the likelihood of detecting volumetric differences in either structure. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2004-04-01

    Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway

    ✓ Peer-reviewed Inflammation and the immune system Experimental cell research

    Key finding: However, the precise implications of inflammatory response for neurodegeneration have not been elucidated. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2004-04-01

    [Validation of a screening test for age associated cognitive impairment, in Chile]

    ✓ Peer-reviewed Cognitive tests and assessment Revista medica de Chile

    Key finding: The real prevalence of dementia in a given population must be determined through prevalence studies, using validated screening tests. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2004-04-01

    Biomarkers of Alzheimer disease in plasma

    ✓ Peer-reviewed Risk genes beyond APOE NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: Most proteins or metabolites evaluated in plasma or serum thus far are, at best, biological correlates of AD: levels are statistically different in AD versus controls in some cohorts, but they lack sensitivity or specificity for diagnosis or for tracking response to therapy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2004-04-01

    Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Here, we show that in Drosophila, the targeted expression of the key genes of AD, APP, the beta-site APP-cleaving enzyme BACE, and the presenilins led to the generation of beta-amyloid plaques and age-dependent neurodegeneration as well as to semilethality, a shortened life span, and defects in wing vein development. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2004-04-01

    Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE European journal of pharmacology

    Key finding: Etiologically, two different types or even more exist. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2004-04-01

    Insulin and the insulin receptor in experimental models of learning and memory

    ✓ Peer-reviewed Risk factors European journal of pharmacology

    Key finding: While the insulin/insulin receptor associated with the hypothalamus plays important roles in regulation of the body energy homeostasis, the hippocampus- and cerebral cortex-distributed insulin/insulin receptor has been shown to be involved in brain cognitive functions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2004-04-01

    Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit

    ✓ Peer-reviewed How common it is JAMA

    Key finding: Of 275 patients, 51 (18.5%) had persistent coma and died in the hospital. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2004-04-01

    A multinational review of recent trends and reports in dementia caregiver burden

    ✓ Peer-reviewed Caregiving Alzheimer disease and associated disorders

    Key finding: In particular, we explore the impact of cultural expectations on five important questions: 1) Do the characteristics of dementia affect caregiver burden? 2) Do characteristics of the caregiver independently predict burden? 3) Does the caregiver affect patient outcomes? 4) Does support or intervention for caregiver result in reduced caregiver burden or improved patient outcomes? 5) Finally, do patient interventions result in reduced caregiver burden or improved patient outcomes? +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2004-04-01

    Cerebrospinal fluid protein biomarkers for Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: Some candidate AD biomarkers including ubiquitin, neurofilament proteins, growth-associated protein 43 (neuromodulin), and neuronal thread protein (AD7c) show interesting results but have been less extensively studied. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2004-04-01

    Amnestic MCI or prodromal Alzheimer's disease?

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: We suggest that it will soon be possible (if it is not already) to identify the underlying pathological disorders before the affected patients meet the criteria of dementia, thanks to specific neuropsychological assessments, neuroimaging, and biomarkers.

    Full summary, score breakdown and related studies → Original source

  17. 2004-04-01

    Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: Cerebral infarctions independently contribute to the likelihood of dementia but do not interact with AD pathology to increase the likelihood of dementia beyond their additive effect. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2004-04-01

    Survival after initial diagnosis of Alzheimer disease

    ✓ Peer-reviewed Getting a diagnosis Annals of internal medicine

    Key finding: The median survival from initial diagnosis was 4.2 years for men and 5.7 years for women with Alzheimer disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2004-04-01

    Aberrant phosphorylation of alpha-synuclein in human Niemann-Pick type C1 disease

    ✓ Peer-reviewed Genetics Journal of neuropathology and experimental neurology

    Key finding: Since AD is frequently associated with neuronal expression of alpha-synuclein, we investigated phosphorylated alpha-synuclein (psyn) immunoreactivity in the brains of 12 NPC1 patients, ages at death ranging from 9 months to 55 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

March 2004 6

  1. 2004-03-21

    Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

    ✓ Peer-reviewed Lewy body dementia Nature genetics

    Key finding: Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD) is a dominant progressive disorder that maps to chromosome 9p21.1-p12. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2004-03-19

    Diet‐induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

    ✓ Peer-reviewed Risk factors The FASEB Journal

    Key finding: Recent epidemiological evidence indicates that insulin resistance, a proximal cause of Type II diabetes [a non-insulin dependent form of diabetes mellitus (NIDDM)], is associated with an increased relative risk for Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2004-03-17

    Androgens, apoE, and Alzheimer's disease

    ✓ Peer-reviewed Genetics Science of aging knowledge environment : SAGE KE

    Key finding: Increasing evidence indicates that there are reductions in estrogen and androgen levels in aged men and women.

    Full summary, score breakdown and related studies → Original source

  4. 2004-03-15

    Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI

    ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences

    Recent functional imaging studies have revealed coactivation in a distributed network of cortical regions that characterizes the resting state, or default mode, of the human brain.

    Full summary, score breakdown and related studies → Original source

  5. 2004-03-09

    Behavioral disorders in the frontal and temporal variants of frontotemporal dementia

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: Both variants of FTD showed significant increases in rates of elation, disinhibition, and aberrant motor behavior compared with AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2004-03-09

    Emerging Therapies for Vascular Dementia and Vascular Cognitive Impairment

    ✓ Peer-reviewed Treatments Stroke

    Key finding: From a public health viewpoint, recognition of VCI before the development of dementia and correction of vascular burden on the brain may lead to a global decrease of incident dementia.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →