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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,901–26,925 of 27,380 studies, newest first · page 1077 of 1096.

January 1992 7

  1. 1992-01-01

    Speech monitoring skills in Alzheimer's disease, Parkinson's disease, and normal aging

    ✓ Peer-reviewed Digital health tools Brain and language

    Key finding: We examined the abilities of 15 patients with dementia of the Alzheimer type (DAT), 22 patients with Parkinson's Disease (PD), and 141 healthy subjects (ranging in age from 30 to 79 years) to detect and correct their own speech errors.

  2. 1992-01-01

    Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study

    ✓ Peer-reviewed How common it is Neurology

    Key finding: The prevalence of dementia was 30.5/1,000 for men and 48.2/1,000 for women and increased with advancing age. +4 more findings

  3. 1992-01-01

    Incontinence and troublesome behaviors predict institutionalization in dementia

    ✓ Peer-reviewed Caregiving Journal of geriatric psychiatry and neurology

    Key finding: After follow-up of 19 +/- 12 months, 51 patients had been institutionalized. +4 more findings

  4. 1992-01-01

    Melas: an original case and clinical criteria for diagnosis

    ✓ Peer-reviewed Getting a diagnosis Neuromuscular disorders : NMD

    Key finding: The syndrome should be suspected by the following three invariant criteria: (1) stroke-like episode before age 40 yr; (2) encephalopathy characterized by seizures, dementia, or both; and (3) lactic acidosis, ragged-red fibers (RRF), or both. +4 more findings

  5. 1992-01-01

    MR-based hippocampal volumetry in the diagnosis of Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: The volumetric measurements of both the normalized ATL and HF were significantly smaller (p less than 0.001) in DAT patients (N = 20) than in controls (N = 22), but the HF volumes provided much better separation between the two groups. +2 more findings

  6. 1992-01-01

    Aluminium and the pathogenesis of Alzheimer's disease: a summary of evidence

    ✓ Peer-reviewed Treatments Ciba Foundation symposium

    Key finding: The principal outcome was that the mean slope for performance of the skills of daily living for the group without treatment was -1.72% maximum score/month, compared to -0.87% maximum score/month for the group treated with desferrioxamine (P = 0.038).

  7. 1992-01-01

    Clinical studies with oxiracetam in patients with dementia of Alzheimer type and multi-infarct dementia of mild to moderate degree

    ✓ Peer-reviewed Treatments Neuropsychobiology

    Key finding: At the end of therapy, statistical analysis evidenced significant improvements in the group receiving oxiracetam in respect to the placebo group on Mini Mental State Examination, Auditory Continuous Performance Test, Rey's 15 Words Test, Block Tapping Test, Mattis Word Fluency, Luria Alternating Series and Instrumental Activities of Daily Living. +2 more findings

December 1991 4

  1. 1991-12-01

    Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Microglial cells and astrocytes are closely associated with nearly all compact deposits of the amyloid beta-protein found in the senile plaques characteristic of Alzheimer's disease and trisomy 21. +3 more findings

  2. 1991-12-01

    Circadian rhythm disorders in sleep-waking and body temperature in elderly patients with dementia and their treatment

    ✓ Peer-reviewed Clinical safety Sleep

    Key finding: These observations indicate that behavioral disorders such as delirium, agitation or wandering in patients with severe dementia might be closely related to disrupted biological rhythms of sleep-waking and the autonomic system (body temperature).

  3. 1991-12-01

    Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Lysosomes, which contain a wide variety of proteases (cathepsins) and other acid hydrolases, are major sites for the turnover of membrane proteins and other cell constituents. +3 more findings

  4. 1991-12-01

    Prevalence of Alzheimer's disease and other dementias in an elderly urban population: relationship with age, sex, and education

    ✓ Peer-reviewed How common it is Neurology

    Key finding: In contrast to previously reported data, we found the same proportion of AD and vascular dementia in the different age strata, and no sex differences regarding the prevalence of different dementia types.

November 1991 6

  1. 1991-11-01

    The Neuropathologic Basis of Different Clinical Subgroups of Parkinson's Disease

    ✓ Peer-reviewed Risk factors Journal of Neuropathology & Experimental Neurology

    Key finding: The AR-type (compared with the T-type) showed higher neuronal loss of LC, SNL, SNM, and more severe gliosis, extraneuronal melanin deposits, and neuroaxonal dystrophy in substantia nigra. +2 more findings

  2. 1991-11-01

    A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities

    ✓ Peer-reviewed Drug development The Biochemical journal

    Key finding: Our results further support the notion that PHF contain abnormally phosphorylated tau in an aggregated state, and indicate that these abnormally phosphorylated tau forms are composed of several tau isoforms and that the full length of the tau molecule is present in these polypeptides.

  3. 1991-11-01

    Hippocampal neuron number in schizophrenia. A stereological study

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of general psychiatry

    Key finding: Total hippocampal volume was reduced in the schizophrenic sample, more pronounced on the left side, but mean differences were not significant. +1 more finding

  4. 1991-11-01

    Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites

    ✓ Peer-reviewed Risk genes beyond APOE Brain research

    Key finding: Using immunofluorescence, laser confocal microscopy and immunoelectron microscopy with simultaneous detection of APP and synaptophysin, we now report a preferential localization of APP at synaptic sites of human and rat brain and at neuromuscular junctions. +2 more findings

  5. 1991-11-01

    The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: These findings indicate that although KPI- APP mRNA is abundant in brain, little corresponding protein is present.

  6. 1991-11-01

    Development and validation of a model for estimating premorbid verbal intelligence in the elderly

    ✓ Peer-reviewed Getting a diagnosis Journal of clinical and experimental neuropsychology

    Key finding: Double cross validation showed that the model had high accuracy and stability in estimating current VIQ in nondemented subjects.

October 1991 6

  1. 1991-10-01

    Psychiatric disorders in persons with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of nervous and mental disease

    Key finding: The overall frequency of psychiatric disorders in our study population was 22.1%.

  2. 1991-10-01

    Autosomal dominant syndrome with strokelike episodes and leukoencephalopathy

    ✓ Peer-reviewed Risk factors Stroke

    Key finding: There appears to be a new syndrome in this family that is characterized by recurrent subcortical strokelike episodes, leukoencephalopathy, immunologic anomalies, muscular lipidosis, and an autosomal dominant pattern of transmission.

  3. 1991-10-01

    A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Although most cases of Alzheimer's disease are sporadic, kindreds with autosomal-dominant inheritance of the syndrome suggest that a single mutation may be important in pathogenesis. +1 more finding

  4. 1991-10-01

    Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

    ✓ Peer-reviewed Risk genes beyond APOE Nature

    Key finding: Direct sequencing of exon 17 in affected individuals from this family has revealed a base change producing a Val----Gly substitution, also at codon 717.

  5. 1991-10-01

    Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

    ✓ Peer-reviewed Brain tissue and pathology Annals of Neurology

    Key finding: We present here both linear regressions and multivariate analyses correlating three global neuropsychological tests with a number of structural and neurochemical measurements performed on a prospective series of 15 patients with Alzheimer's disease and 9 neuropathologically normal subjects. +3 more findings

  6. 1991-10-01

    Ageing and Parkinson's disease: substantia nigra regional selectivity

    ✓ Peer-reviewed Lewy body dementia Brain : a journal of neurology

    Key finding: Regionally, the lateral ventral tier was relatively spared (2.1% loss per decade) compared with the medial ventral tier (5.4%) and the dorsal tier (6.9%). +1 more finding

September 1991 2

  1. 1991-09-15

    Postmenopausal Estrogen and Prevention Bias

    ✓ Peer-reviewed Clinical trials Annals of Internal Medicine

    Key finding: Brief Report15 September 1991Postmenopausal Estrogen and Prevention BiasElizabeth Barrett-Connor, MDElizabeth Barrett-Connor, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-6-455 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the last decade many investigators reported that postmenopausal women taking estrogen were at reduced risk for cardiovascular disease compared with women not taking estrogen (1). +2 more findings

  2. 1991-09-01

    Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine

    ✓ Peer-reviewed Drug development Archives of internal medicine

    Key finding: We used a two-round survey, based on Delphi methods, with 13 nationally recognized experts to reach consensus on explicit criteria defining the inappropriate use of medications in a nursing home population. +4 more findings

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