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52/100

✓ Peer-reviewed alzhub usefulness score 52 out of 100. Getting a diagnosis

Topic: Risk, prevention and care in population studies

We will assess the utility of auditory perceptual tests, both alone and combined with blood-based biomarkers (pTau217 and NfL), for diagnosis and prognosis in individuals with cognitive symptoms. Additionally, we will examine the cultural fairness and cost-effectiveness of this approach This research aims to revolutionize early dementia diagnosis by developing scalable, culture-fair and precise digital tools based on the measurement of auditory cognition. We aim to improve access to timely and equitable dementia diagnosis and support early treatment and care interventions.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Durrani, F. G., Marshall, C. R., Waters, S., Bishop, L., Lim, D. G., Smith, L. J., et al. (2025). (DIADEM) Digital Assessment of Auditory Perception in Dementia : Study Protocol. Alzheimer s & Dementia. https://doi.org/10.1002/alz70856_098358

Vancouver

Durrani FG, Marshall CR, Waters S, Bishop L, Lim DG, Smith LJ, et al. (DIADEM) Digital Assessment of Auditory Perception in Dementia : Study Protocol. Alzheimer s & Dementia. 2025. doi:10.1002/alz70856_098358. PMID: 41441593.

BibTeX

@article{durrani2025-41441593,
  author  = {Durrani, Faiza Gul and Marshall, Charles R. and Waters, Sheena and Bishop, Lauren and Lim, Dicky G and Smith, Laura Jennie and Chemas, Natalia and Uchegbu, Ijeoma and others},
  title   = {{(DIADEM) Digital Assessment of Auditory Perception in Dementia : Study Protocol}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70856_098358},
  pmid    = {41441593},
  url     = {https://doi.org/10.1002/alz70856_098358}
}

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Key findings

We will assess the utility of auditory perceptual tests, both alone and combined with blood-based biomarkers (pTau217 and NfL), for diagnosis and prognosis in individuals with cognitive symptoms.
Additionally, we will examine the cultural fairness and cost-effectiveness of this approach This research aims to revolutionize early dementia diagnosis by developing scalable, culture-fair and precise digital tools based on the measurement of auditory cognition.
We aim to improve access to timely and equitable dementia diagnosis and support early treatment and care interventions.

Why it matters

This is a study protocol, so no results are available yet on whether auditory tests combined with blood biomarkers can diagnose dementia. It aims to test whether these digital tools are accurate, culturally fair, and cost-effective for early diagnosis.

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Study details

Study designcohort study
Participants600
Effect sizeAUC 0.91
Evidence strengthModerate

How this study scored 52/100

Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for randomised / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 50 of the 96 points we could judge it on, which is 52 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Alzheimer s & Dementia)
Journal's citation record	2 / 4	Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)
Study design	7 / 12	A cohort study following people over time
Strength of evidence	3 / 5	Rated “moderate” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	4 / 5	2025 — within 3 year(s) of the newest study here
Sample size	2 / 4	600 participants
Effect reported	3 / 3	Effect reported with a statistic (interval, p-value, ratio or similar)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	1 / 7	Cited 1 times (OpenAlex, 2026-10-10)
Citations per year	0 / 5	0.3 citations a year over 3 year(s) since 2025
Impact for its field and year	1 / 6	Cited 0.6× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	0 / 6	No other study in this library cites it
Still being cited	0 / 4	Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	— / 4	OpenAlex's profile for last-listed author Nicholas Bass holds only 9 work(s), too few to judge a track record — left out of this score
Institution's track record	2 / 3	University College London: institution h-index 2,029 (OpenAlex)
Multi-centre collaboration	1 / 3	OpenAlex lists 3 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 41441593)
Free to read	2 / 2	Free to read
Points	50 / 96	Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 50 of the 96 points we could judge it on is 52 out of 100.
Total	52 / 100	—

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