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Comparison of the Montreal Cognitive Assessment and the Mini‐Mental State Examination in community‐dwelling very old Blacks/African Americans
Elizabeth Guerrero‐Berroa, Kim Love, Ruby S. C. Phillips, Vahram H. Haroutunian. Alzheimer s & Dementia, 2025-12-01
Topic: Risk, prevention and care in population studies
Plain-language summary
Participants had age mean = 81.7, SD = 4.5, range=75-93; educational attainment mean = 14.6, SD = 4.0, range=7-22, 17.2% < 12; 86.2% were women. The MoCA score had mean = 22.2, SD = 4.0, range=14-27; MMSE score had mean = 27.2, SD = 2.1, range = 22-30. Among those with educational attainment below high school (n = 5), MoCA score had mean = 15.6, SD=1.5, median = 15.0, range=14-18; and MMSE score had mean = 25.0, SD = 2.3, median = 26, range=22-27. While higher MoCA score was significantly associated with younger age (r = -.406, p = .029) and higher education (r = .496, p = .006), MMSE associations were nonsignificant for age and education (r = -.313, p = .098; r=.328, p = .083, respectively). MoCA and MMSE were significantly associated (partial r=.425, p = .027). Consistent with previous findings in young-old Blacks/African Americans compared to their White counterparts, our very old sample showed poorer performance on the MoCA compared to the MMSE. These results were strongest among those who did not complete a high school degree. In this population, false-positive results can be minimized with careful interpretation of both MoCA and MMSE performance. Due to the small sample, these results should be interpreted with caution. However, they do suggest that, until better screening tools are developed for this population, researchers and clinicians should consider the use of the MMSE.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Guerrero‐Berroa, E., Love, K., Phillips, R. S. C., & Haroutunian, V. H. (2025). Comparison of the Montreal Cognitive Assessment and the Mini‐Mental State Examination in community‐dwelling very old Blacks/African Americans. Alzheimer s & Dementia. https://doi.org/10.1002/alz70860_103916
Vancouver
Guerrero‐Berroa E, Love K, Phillips RSC, Haroutunian VH. Comparison of the Montreal Cognitive Assessment and the Mini‐Mental State Examination in community‐dwelling very old Blacks/African Americans. Alzheimer s & Dementia. 2025. doi:10.1002/alz70860_103916. PMID: 41434408.
BibTeX
@article{guerreroberroa2025-41434408,
author = {Guerrero‐Berroa, Elizabeth and Love, Kim and Phillips, Ruby S. C. and Haroutunian, Vahram H.},
title = {{Comparison of the Montreal Cognitive Assessment and the Mini‐Mental State Examination in community‐dwelling very old Blacks/African Americans}},
journal = {Alzheimer s \& Dementia},
year = {2025},
doi = {10.1002/alz70860_103916},
pmid = {41434408},
url = {https://doi.org/10.1002/alz70860_103916}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Participants had age mean = 81.7, SD = 4.5, range=75-93; educational attainment mean = 14.6, SD = 4.0, range=7-22, 17.2% < 12; 86.2% were women.
- The MoCA score had mean = 22.2, SD = 4.0, range=14-27; MMSE score had mean = 27.2, SD = 2.1, range = 22-30.
- Among those with educational attainment below high school (n = 5), MoCA score had mean = 15.6, SD=1.5, median = 15.0, range=14-18; and MMSE score had mean = 25.0, SD = 2.3, median = 26, range=22-27.
- While higher MoCA score was significantly associated with younger age (r = -.406, p = .029) and higher education (r = .496, p = .006), MMSE associations were nonsignificant for age and education (r = -.313, p = .098; r=.328, p = .083, respectively).
- MoCA and MMSE were significantly associated (partial r=.425, p = .027).
Why it matters
In this small sample of very old Black/African American adults, MoCA scores were lower than MMSE scores, especially among those without a high school degree, and MoCA was associated with age and education while MMSE was not. The authors caution that results should be interpreted with caution due to the small sample, and the study addresses cognitive screening rather than treatment or prevention.
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Study details
- Effect size17.2%; 86.2%
- Evidence strengthLow
How this study scored 39/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Vahram H. Haroutunian: h-index 107 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Icahn School of Medicine at Mount Sinai: institution h-index 1,331 (OpenAlex) |
| Multicenter collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41434408) |
| Free to read | 2 / 2 | Free to read |
| Total | 39 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1002/alz70860_103916
- PubMed: 41434408
- Original source →
- Free full text: Alzheimer s & Dementia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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