alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,301–21,325 of 27,380 studies, newest first · page 853 of 1096.

September 2009 2

  1. 2009-09-01

    Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial)

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Overall, 318 patients with AD completed BPST with an improvement of 5.6 points on the total Cohen-Mansfield Agitation Inventory (CMAI; mean [SD], 63.3 [16.0] to 57.7 [18.4], t = 4.8, df = 317, p 95% of patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2009-09-01

    Effect of a CYP2D6 polymorphism on the efficacy of donepezil in patients with Alzheimer disease

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The single nucleotide polymorphism rs1080985 in the CYP2D6 gene may influence the clinical efficacy of donepezil in patients with mild to moderate Alzheimer disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

August 2009 23

  1. 2009-08-26

    Air pollution: mechanisms of neuroinflammation and CNS disease

    ✓ Peer-reviewed Risk factors Trends in neurosciences

    Key finding: While mechanisms driving air pollution-induced CNS pathology are poorly understood, new evidence suggests that microglial activation and changes in the blood-brain barrier are key components.

    Full summary, score breakdown and related studies → Original source

  2. 2009-08-26

    Population normative data for the 10/66 Dementia Research Group cognitive test battery from Latin America, India and China: a cross-sectional survey

    ✓ Peer-reviewed Disparities BMC neurology

    Key finding: Cognitive assessment is a basic element for dementia diagnosis. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2009-08-22

    Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging

    ✓ Peer-reviewed Prevention trials Experimental neurology

    Key finding: In a previous longitudinal study, we demonstrated that aged dogs treated with either an antioxidant diet or with behavioral enrichment show cognitive improvement. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2009-08-21

    Functional neural network analysis in frontotemporal dementia and Alzheimer's disease using EEG and graph theory

    ✓ Peer-reviewed Digital health tools BMC neuroscience

    Key finding: With decreasing local and global connectivity parameters, the large-scale functional brain network organization in AD deviates from the optimal 'small-world' network structure towards a more 'random' type. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2009-08-21

    Palliative Access Through Care at Home: experiences with an urban, geriatric home palliative care program

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Caregivers for the elderly, mostly African-American patients, more than half of whom had dementia, were overall very satisfied with their experience, despite the large amount of time necessary to provide the care that patients required.

    Full summary, score breakdown and related studies → Original source

  6. 2009-08-21

    The northwestern anagram test: measuring sentence production in primary progressive aphasia

    ✓ Peer-reviewed Digital health tools American journal of Alzheimer's disease and other dementias

    Key finding: Northwestern Anagram Test performance was significantly correlated with a measure of sentence production and with aphasia severity but not with measures of naming, single word comprehension, object recognition, or motor speech.

    Full summary, score breakdown and related studies → Original source

  7. 2009-08-20

    Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice

    ✓ Peer-reviewed Risk genes beyond APOE Neuroscience letters

    Key finding: To evaluate the potential of CR to protect against relatively heavy AD-type pathology, middle-aged (13-14-month-old) mice that co-express two mutations related to familial AD, amyloid precursor protein (APP) and presenilin 1 (PS1), were fed balanced diets with 40% fewer calories than ad libitum-fed controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2009-08-20

    Making sense of progressive non-fluent aphasia: an analysis of conversational speech

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: The study suggests that PNFA is a coherent, well-defined syndrome and that varieties such as logopaenic progressive aphasia and progressive apraxia of speech may be seen as points in a space of continuous variation within progressive non-fluent aphasia.

    Full summary, score breakdown and related studies → Original source

  9. 2009-08-19

    Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study

    ✓ Peer-reviewed Prevention and risk Journal of neurology, neurosurgery, and psychiatry

    Key finding: During follow-up, 203 cases of hospitalisation with dementia were identified. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2009-08-18

    Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding

    ✓ Peer-reviewed Tau biomarkers Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: The purpose of this study was to investigate the potential relationships between cerebrospinal fluid (CSF) measurements of beta-amyloid-1-42 (Abeta(1-42)) and total tau to (11)C-Pittsburgh compound B ((11)C-PiB) and 2-(1-{6-[(2-(18)F-fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene) malononitrile ((18)F-FDDNP) binding as measured using PET. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2009-08-14

    Function and regulation of Dyrk1A: towards understanding Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Cellular and molecular life sciences : CMLS

    Key finding: Down syndrome (DS) is associated with a variety of symptoms, such as incapacitating mental retardation and neurodegeneration (i.e., Alzheimer's disease), that prevent patients from leading fully independent lives. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2009-08-13

    Hippocampal volume assessment in temporal lobe epilepsy: How good is automated segmentation?

    ✓ Peer-reviewed Hippocampus size on brain scans Epilepsia

    Key finding: Expert manual hippocampal volumetry is more sensitive than both automated methods for the detection of hippocampal atrophy associated with mTLE. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2009-08-13

    Subjective memory complaints and awareness of memory functioning in mild cognitive impairment: a systematic review

    ✓ Peer-reviewed Mild cognitive impairment Dementia and geriatric cognitive disorders

    Key finding: Given the increased risk of progression to dementia for those identified as having MCI, the role of awareness should be explored further with due consideration given to the conceptualization of awareness and the methodology employed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2009-08-12

    Improving decision making at the end of life with video images

    ✓ Peer-reviewed End-of-life care Medical decision making : an international journal of the Society for Medical Decision Making

    Key finding: Subjects with limited health literacy expressed more uncertainty about their preferences for end-of-life care than did subjects with adequate literacy.

    Full summary, score breakdown and related studies → Original source

  15. 2009-08-12

    Concentrations of metals, beta-amyloid and tau-markers in cerebrospinal fluid in patients with Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders

    Key finding: The AD subjects showed positive correlations between CSF-T-tau and CSF-P-tau versus CSF-Mn (r(s) = 0.22, p = 0.004; r(s) = 0.18, p = 0.021). +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2009-08-11

    A new subtype of frontotemporal lobar degeneration with FUS pathology

    ✓ Peer-reviewed Lewy body dementia Brain : a journal of neurology

    Key finding: The neuropathology associated with most FTD is characterized by abnormal cellular aggregates of either transactive response DNA-binding protein with Mr 43 kDa (TDP-43) or tau protein. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2009-08-11

    Progressive logopenic/phonological aphasia: erosion of the language network

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: The primary progressive aphasias (PPA) are paradigmatic disorders of language network breakdown associated with focal degeneration of the left cerebral hemisphere. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2009-08-10

    Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

    ✓ Peer-reviewed Prevention and risk Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Mitochondrial amyloid beta (Abeta) level in the 3xTg-AD mice was significantly increased at 9 months and temporally correlated with increased level of Abeta binding to alcohol dehydrogenase (ABAD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2009-08-10

    Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

    ✓ Peer-reviewed Clinical trials Nutrition & metabolism

    Key finding: AC-1202 was compared to Placebo in several population groups, including: intention-to-treat (ITT), per protocol, and dosage compliant groups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2009-08-07

    Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

    ✓ Peer-reviewed Genetics PloS one

    Key finding: Using hippocampal atrophy as a quantitative phenotype in a genome-wide scan, we have identified candidate risk genes for sporadic Alzheimer's disease that merit further investigation.

    Full summary, score breakdown and related studies → Original source

  21. 2009-08-04

    Pravastatin and cognitive function in the elderly. Results of the PROSPER study

    ✓ Peer-reviewed Drug development Journal of neurology

    Key finding: Observational studies have given conflicting results about the effect of statins in preventing dementia and cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2009-08-04

    Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

    ✓ Peer-reviewed Disease mechanisms Human molecular genetics

    Key finding: However, F1 does not fully enter the lysosome but remains associated with the lysosomal membrane.

    Full summary, score breakdown and related studies → Original source

  23. 2009-08-04

    Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later

    ✓ Peer-reviewed How common it is Dementia and geriatric cognitive disorders

    Key finding: Midlife serum total cholesterol was associated with an increased risk of AD and VaD. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →