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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,801–23,825 of 27,380 studies, newest first · page 953 of 1096.

January 2005 25

  1. 2005-01-24

    Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study

    ✓ Peer-reviewed Vascular contributions BMJ (Clinical research ed.)

    Key finding: Older adults with dementia who take atypical antipsychotics have a similar risk of ischaemic stroke to those taking typical antipsychotics.

    Full summary, score breakdown and related studies → Original source

  2. 2005-01-15

    Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model

    ✓ Peer-reviewed Treatments Psychopharmacology

    Key finding: All cholinesterase inhibitors reduced cognitive deficits with the following optimal daily doses: galantamine 1.25 mg kg(-1), rivastigmine 0.5 mg kg(-1) and donepezil 0.3 mg kg(-1). +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2005-01-14

    Death receptor signaling

    ✓ Peer-reviewed Disease mechanisms Journal of Cell Science

    Key finding: Triggering members of the DR family by death ligands results in the transduction of either apoptotic or survival signals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2005-01-11

    Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK

    ✓ Peer-reviewed Risk genes beyond APOE PLoS medicine

    Key finding: Recent evidence suggests that statin use may be associated with a decreased risk for Alzheimer disease, although the mechanisms underlying this apparent risk reduction are poorly understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2005-01-07

    Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport

    ✓ Peer-reviewed Inflammation and the immune system The Journal of biological chemistry

    Key finding: Activated microglia have been observed around degenerative neurons in these diseases, and they are thought to act as effector cells in the degeneration of neural cells in the central nervous system. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2005-01 month only

    Everyday ethics in assisted living facilitites: a framework for assessing resident-focused issues

    ✓ Peer-reviewed Health systems and care delivery Journal of gerontological nursing

    Key finding: This article describes and illustrates a framework that may be used when assessing the moral basis of everyday issues that can affect residents of assisted living facilities. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2005 year only

    Spiritual well-being and caregiver burden in Alzheimer's caregivers

    ✓ Peer-reviewed Caregiving Geriatric nursing (New York, N.Y.)

    Key finding: Additional findings revealed significant differences in African American and Caucasian caregiver's perception of spiritual well-being and caregiver burden.

    Full summary, score breakdown and related studies → Original source

  8. 2005-01-01

    Natural products and derivatives affecting neurotransmission relevant to Alzheimer's and Parkinson's disease

    ✓ Peer-reviewed End-of-life care Neuro-Signals

    Key finding: Natural products continue to provide useful drugs in their own right but also provide templates for the development of other compounds. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2005-01-01

    The binding of thioflavin-T to amyloid fibrils: localisation and implications

    ✓ Peer-reviewed Prevention and risk Journal of structural biology

    Key finding: Confocal microscopy studies of thioflavin-T aligned in stretched poly-vinyl alcohol films showed that the dye dipole excitation axis lies parallel to the long molecular axis.

    Full summary, score breakdown and related studies → Original source

  10. 2005-01-01

    ER stress and the unfolded protein response

    ✓ Peer-reviewed Risk factors Mutation research

    Key finding: The UPR increases the biosynthetic capacity of the secretory pathway through upregulation of ER chaperone and foldase expression. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2005-01-01

    Metals, toxicity and oxidative stress

    ✓ Peer-reviewed Risk factors Current medicinal chemistry

    Key finding: Common mechanisms involving the Fenton reaction, generation of the superoxide radical and the hydroxyl radical appear to be involved for iron, copper, chromium, vanadium and cobalt primarily associated with mitochondria, microsomes and peroxisomes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2005-01-01

    Class II G protein-coupled receptors and their ligands in neuronal function and protection

    ✓ Peer-reviewed Drug development Neuromolecular medicine

    Key finding: Studies of patients and animal and cell culture models, have revealed possible roles for class II GPCRs signaling in the pathogenesis of several prominent neurodegenerative conditions including stroke, Alzheimer's, Parkinson's, and Huntington's diseases.

    Full summary, score breakdown and related studies → Original source

  13. 2005-01-01

    Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you

    ✓ Peer-reviewed Brain scans and imaging Annual review of cell and developmental biology

    Key finding: In contrast to other tissues, the nervous system is enriched in the polyunsaturated fatty acids (PUFAs): arachidonic acid (AA, 20:4 n-6) and docosahexaenoic acid (DHA, 22:6 n-3). +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2005-01-01

    Imaging iron stores in the brain using magnetic resonance imaging

    ✓ Peer-reviewed Brain scans and imaging Magnetic resonance imaging

    Key finding: As there are many forms of iron in the brain, separating them and quantifying each type have been a major challenge. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2005-01-01

    Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios

    ✓ Peer-reviewed Biomarkers Journal of neurochemistry

    Key finding: Gene knockout studies in mice suggest that presenilin 1 (PS1) is the major gamma-secretase and that it contributes disproportionately to amyloid beta (Abeta) peptide generation from beta-amyloid precursor protein (APP), whereas PS2 plays a more minor role. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2005-01-01

    Dementia of Alzheimer's disease and other neurodegenerative disorders--memantine, a new hope

    ✓ Peer-reviewed Vascular contributions Pharmacological research

    Key finding: Memantine is also reported to have beneficial effects in other CNS disorders viz., Parkinson's disease (PD), stroke, epilepsy, CNS trauma, amyotrophic lateral sclerosis (ALS), drug dependence and chronic pain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2005-01-01

    Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs

    ✓ Peer-reviewed Hippocampus size on brain scans Current pharmaceutical design

    Key finding: The birth of new neurons, or neurogenesis, in the hippocampal formation has been demonstrated throughout the lifetime of multiple species including humans. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2005-01-01

    Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies

    ✓ Peer-reviewed Hippocampus size on brain scans Hippocampus

    Key finding: Over the last decade a significant number of studies have reported smaller hippocampal volume in individuals with symptoms of post-traumatic stress disorder (PTSD) relative to control groups, and in some cases hemispheric asymmetries in this effect have been noted. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2005-01-01

    Evaluation of an educational program for long-term care nursing assistants

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: This pilot project demonstrates that a staff educational program on end-of-life care for dementia residents can improve end-of-life knowledge and attitudes among long-term care ancillary staff and that this improvement can be maintained for up to 1 year. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2005-01-01

    Cost of illness and its predictors for Parkinson's disease in Germany

    ✓ Peer-reviewed Clinical safety PharmacoEconomics

    Key finding: We estimated average per patient direct, indirect and total costs for the 6-month observation period. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2005 no date recorded — placed by publication year

    Measures of brain morphology and infarction in the framingham heart study: establishing what is normal

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of Aging

    Full summary, score breakdown and related studies → Original source

  22. 2005-01-01

    Serum cholesterol and cognitive performance in the Framingham Heart Study

    ✓ Peer-reviewed Long-term cohort studies Psychosomatic medicine

    Key finding: The objective of this study was to examine the relationship between total cholesterol (TC) and cognitive performance within the context of the Framingham Heart Study, a large, community-based, prospective investigation of cardiovascular risk factors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2005-01-01

    [The estimation of premorbid intelligence levels in French speakers]

    ✓ Peer-reviewed Cognitive tests and assessment L'Encephale

    Key finding: Knowledge of cognitive performance earlier in life is essential in order to characterize precisely the extent to which these abilities have declined when an individual is diagnosed as having a dementing illness. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2005-01-01

    Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Neuropsychologia

    Key finding: Therefore, the hypothesis of this study is that an imbalance between the cholinergic and serotonergic systems is related to cognitive symptoms and psychological syndromes of dementia (BPSD) in patients with AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2005-01-01

    Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neuroscience research

    Key finding: The assumption has been made that drugs that protect mitochondrial viability and prevent apoptotic cascade-induced mitochondrial permeability transition pore (MPTp) opening will be cytoprotective. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →