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Midlife psychological stress and risk of dementia: a 35-year longitudinal population study
Johansson L, Guo X, Waern M, Ostling S, Gustafson D, Bengtsson C, Skoog I.. Brain : a journal of neurology, 2010-05-20
Topic: Risk, prevention and care in population studies
The number of people with dementia has increased dramatically with global ageing. Nevertheless, the pathogeneses of these diseases are not sufficiently understood. The present study aims to analyse the relationship between psychological stress in midlife and the development of dementia in late-life.
Key findings
- Nevertheless, the pathogeneses of these diseases are not sufficiently understood.
- The present study aims to analyse the relationship between psychological stress in midlife and the development of dementia in late-life.
- A representative sample of females (n = 1462) aged 38-60 years were examined in 1968-69 and re-examined in 1974-75, 1980-81, 1992-93 and 2000-03.
- Psychological stress was rated according to a standardized question in 1968, 1974 and 1980.
Why it matters
This study analysed whether psychological stress in midlife is related to developing dementia in later life in a sample of 1,462 women. It examines a possible risk relationship and offers no treatment, cure or prevention.
Study details
- Participants1,462
- Evidence strengthLow
How this study scored 54/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Brain : a journal of neurology) |
| Journal's citation record | 4 / 4 | Brain: journal h-index 503 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2010 — within 20 year(s) of the newest study here |
| Sample size | 3 / 4 | 1,462 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 292 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 16.2 citations a year over 18 year(s) since 2010 |
| Impact for its field and year | 3 / 6 | Cited 5.8× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 9 other studies in this library |
| Still being cited | 2 / 4 | Cited 45 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Ingmar Gr. Skoog: h-index 105 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Gothenburg: institution h-index 972 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 20488887) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 54 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Johansson, L., Guo, X., Waern, M., Ostling, S., Gustafson, D., Bengtsson, C., et al. (2010). Midlife psychological stress and risk of dementia: a 35-year longitudinal population study. Brain : a journal of neurology. https://doi.org/10.1093/brain/awq116
Vancouver
Johansson L, Guo X, Waern M, Ostling S, Gustafson D, Bengtsson C, et al. Midlife psychological stress and risk of dementia: a 35-year longitudinal population study. Brain : a journal of neurology. 2010. doi:10.1093/brain/awq116. PMID: 20488887.
BibTeX
@article{johansson2010-20488887,
author = {Johansson, L. and Guo, X. and Waern, M. and Ostling, S. and Gustafson, D. and Bengtsson, C. and Skoog, I.},
title = {{Midlife psychological stress and risk of dementia: a 35-year longitudinal population study}},
journal = {Brain : a journal of neurology},
year = {2010},
doi = {10.1093/brain/awq116},
pmid = {20488887},
url = {https://doi.org/10.1093/brain/awq116}
}
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